MYRIP antibody (AA 101-200)
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- Target See all MYRIP Antibodies
- MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))
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Binding Specificity
- AA 101-200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MYRIP antibody is un-conjugated
- Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MYRIP/SLAC2-C
- Isotype
- IgG
- Top Product
- Discover our top product MYRIP Primary Antibody
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anti-Myosin VIIA and Rab Interacting Protein (MYRIP) (C-Term) antibody
Verified MYRIP Reactivity: Human ELISA, WB, IHC Host: Goat Polyclonal unconjugated
anti-Myosin VIIA and Rab Interacting Protein (MYRIP) (AA 387-689) antibodyMYRIP Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Myosin VIIA and Rab Interacting Protein (MYRIP) (AA 659-686), (C-Term) antibodyMYRIP Reactivity: Human WB Host: Rabbit Polyclonal RB36518 unconjugated
anti-Myosin VIIA and Rab Interacting Protein (MYRIP) (AA 1-859) antibodyMYRIP Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))
- Alternative Name
- MYRIP/SLAC2-C (MYRIP Products)
- Synonyms
- SLAC2-C antibody, SLAC2C antibody, A230081N12Rik antibody, Slac2-c antibody, Slac2c antibody, MYRIP antibody, si:dkey-189e1.4 antibody, LOC100156583 antibody, myosin VIIA and Rab interacting protein antibody, MYRIP antibody, Myrip antibody, myrip antibody
- Background
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Synonyms: exophilin 8, exophilin, Exophilin-8, Exophilin8, Myosin VIIA and Rab interacting protein, Myosin-VIIa- and Rab-interacting protein, MyRIP, MYRIP_HUMAN, rab effector MYRIP, SLAC 2C, SLAC2 C, SLAC2-C, SLAC2C, Slp homolog lacking C2 domains c, Slp homologue lacking C2 domains, Slp homologue lacking C2 domains c antibody Synaptotagmin like protein homologue lacking C2 domains c, synaptotagmin-like protein homologue lacking C2 domains-c.
Background: Slac2-c is a Rab effector protein that is expressed in a variety of tissues including brain, heart, skin and liver. Found in the basal microvilli of retinal pigment cells and in pre- and post-synaptic areas in photoreceptor cells , Slac2-c is involved in melanosome transport and functions to link Rab 27a with the actin-based motor proteins Myosin Va and Myosin VIIa. Once linked, the Myosins are able to transport Rab 27a to retinal melanosomes, thereby linking the actin cytoskeleton with the melanosome membrane. Slac2-c contains one FYVE-type zinc finger and one Rab-binding domain and is able to bind actin-like proteins through its conserved C-terminal region. Additionally, Slac2-c is thought to regulate the final steps of insulin exocytosis by mediating the interaction of secretory granules with the cortical actin cytoskeleton.
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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