TEAD1 antibody (Internal Region)
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- Target See all TEAD1 Antibodies
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TEAD1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- TEAD1 Antibody detects endogenous levels of total TEAD1.
- Predicted Reactivity
- Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TEAD1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TEAD1 Primary Antibody
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anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 135-215) antibody
TEAD1 Reactivity: Human WB, IHC, IF, ChIP Host: Rabbit Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (C-Term) antibodyTEAD1 Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse, Pig, Chicken, Monkey, Bat, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (C-Term) antibodyTEAD1 Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 135-215) antibodyTEAD1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) antibodyTEAD1 Reactivity: Human WB, ChIP, IP Host: Rabbit Monoclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) antibodyTEAD1 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 324-352), (C-Term) antibodyTEAD1 Reactivity: Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal RB20896 unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (N-Term) antibodyTEAD1 Reactivity: Human, Mouse, Rabbit, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 195-244) antibodyTEAD1 Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Pig, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) antibodyTEAD1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl,sodium azide and glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
- Alternative Name
- TEAD1 (TEAD1 Products)
- Synonyms
- tead1 antibody, zgc:63696 antibody, TEAD1 antibody, xtead1 antibody, 2610024B07Rik antibody, B230114H05Rik antibody, Gtrgeo5 antibody, TEAD-1 antibody, TEF-1 antibody, Tcf13 antibody, mTEF-1 antibody, AA antibody, NTEF-1 antibody, REF1 antibody, TCF-13 antibody, TCF13 antibody, XNTEF-1 antibody, xlNTEF-1 antibody, TEA domain family member 1a antibody, TEA domain transcription factor 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) antibody, TEA domain family member 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) S homeolog antibody, TEA domain family member 1b antibody, tead1a antibody, TEAD1 antibody, tead1 antibody, Tead1 antibody, tead1.S antibody, tead1b antibody
- Background
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Description: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
Gene: TEAD1
- Molecular Weight
- 48 kDa
- Gene ID
- 7003
- UniProt
- P28347
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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