Minichromosome Maintenance Complex Component 7 (MCM7) Peptide
MCM7
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all MCM7 products
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MCM7 antibody (Catalog #: ARP36652_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
- Synonyms
- CDC47 Peptide, MCM2 Peptide, P1.1-MCM3 Peptide, P1CDC47 Peptide, P85MCM Peptide, PNAS146 Peptide, MCM7 Peptide, AI747533 Peptide, Mcmd7 Peptide, mCDC47 Peptide, chunp6911 Peptide, nyz175 Peptide, sr:nyz175 Peptide, cdc47 Peptide, cdc47-2 Peptide, mcm7 Peptide, xmcm7 Peptide, CG4978 Peptide, DmMCM7 Peptide, DmeMCM7 Peptide, Dmel\\CG4978 Peptide, McM7 Peptide, Mcp-PCR1 Peptide, PCR1 Peptide, anon-EST:Liang-1.66 Peptide, clone 1.66 Peptide, minichromosome maintenance complex component 7 Peptide, mini-chromosome maintenance complex protein 7 Peptide, minichromosome maintenance complex component 2 Peptide, minichromosome maintenance complex component 7 L homeolog Peptide, Minichromosome maintenance 7 Peptide, minichromosome maintenance complex component 7 S homeolog Peptide, MCM complex subunit Mcm7 Peptide, MCM7 Peptide, CDC47 Peptide, Mcm7 Peptide, MCM2 Peptide, mcm7 Peptide, mcm7.L Peptide, mcm7.S Peptide
- Background
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MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MCM2, CDC47, P85MCM, P1CDC47, PNAS146, P1.1-MCM3
Protein Interaction Partner: RB1,RBL1,RBL2,MCM3,MCM4,MCM7,ATRIP,CCNH,CDC45,CDC6,CDC7,CDK7,CDKN1B,CRLS1,DBF4,FHL2,HIST3H3,MBIP,MCM10,MCM2,MCM3,MCM4,MCM5,MCM6,MCM7,MCM8,MNAT1,NFKBIA,ORC1L,ORC2L,ORC3L,ORC4L,ORC5L,ORC6L,PLK1,RAD17,RB1,RBL1,RBL2,RBM8A,RPA1,SMC1A,UBE3A,ATR,ATRIP,CCNH,CDC45,CDC6,CDC7,CDK7,CDT1,CNOT8,DBF4,FHL2,GIPC1,GSTK1,MBIP,MCM10,MCM2,MCM3,MCM3,MCM4,MCM4,MCM5,MCM6,MCM7,MCM8,MNAT1,MYC,NEK6,ORC1L,ORC2L,ORC3L,ORC5L,PELO,RB1,RBL1,RBL2,RBM8A,RECQL5,RPA1,TH1L,TRAF6,UBE3A
Protein Size: 719 - Molecular Weight
- 81 kDa
- Gene ID
- 4176
- NCBI Accession
- NM_005916, NP_005907
- UniProt
- P33993
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