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CD86 antibody (PE-Cy3)

CD86 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig FACS, WB Host: Rabbit Polyclonal PE-Cy3
Catalog No. ABIN736712
  • Target See all CD86 Antibodies
    CD86
    Reactivity
    • 138
    • 114
    • 49
    • 19
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Human, Mouse, Rat, Dog, Cow, Pig
    Host
    • 77
    • 69
    • 67
    Rabbit
    Clonality
    • 152
    • 58
    • 1
    Polyclonal
    Conjugate
    • 85
    • 23
    • 18
    • 14
    • 13
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD86 antibody is conjugated to PE-Cy3
    Application
    • 144
    • 95
    • 44
    • 41
    • 33
    • 31
    • 30
    • 23
    • 16
    • 16
    • 15
    • 14
    • 13
    • 11
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB)
    Cross-Reactivity
    Dog, Human, Mouse, Rat
    Predicted Reactivity
    Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from rat CD86
    Isotype
    IgG
    Top Product
    Discover our top product CD86 Primary Antibody
  • Application Notes
    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CD86
    Alternative Name
    CD86 (CD86 Products)
    Synonyms
    B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
    Background

    Synonyms: B7-2, Cd86 antigen, Cd86, Membrane glycoprotein

    Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

    Gene ID
    56822
    UniProt
    O35531
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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