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TBC1D7 antibody (AA 1-293)

TBC1D7 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7171658
  • Target See all TBC1D7 Antibodies
    TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 1-293
    Reactivity
    • 25
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 23
    • 2
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    This TBC1D7 antibody is un-conjugated
    Application
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human TBC1 domain family member 7 protein (1-293AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
    Alternative Name
    TBC1D7 (TBC1D7 Products)
    Synonyms
    PIG51 antibody, TBC7 antibody, dJ257A7.3 antibody, 2610009C09Rik antibody, TBC1 domain family member 7 antibody, TBC1 domain family, member 7 antibody, TBC1D7 antibody, Tbc1d7 antibody
    Background

    Background: Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.

    Aliases: TBC1D7 antibody, TBC7 antibody, HSPC239 antibody, TBC1 domain family member 7 antibody, Cell migration-inducing protein 23 antibody

    UniProt
    Q9P0N9
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