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PDHA1 antibody

PDHA1 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259915
  • Target See all PDHA1 Antibodies
    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
    Reactivity
    • 105
    • 52
    • 51
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 102
    • 7
    Rabbit
    Clonality
    • 93
    • 16
    Polyclonal
    Conjugate
    • 40
    • 9
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDHA1 antibody is un-conjugated
    Application
    • 96
    • 44
    • 15
    • 15
    • 14
    • 13
    • 13
    • 11
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PDHA1 (NP_000275.1).
    Isotype
    IgG
    Top Product
    Discover our top product PDHA1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
    Alternative Name
    PDHA1 (PDHA1 Products)
    Synonyms
    PDHA antibody, PDHCE1A antibody, PHE1A antibody, Pdha-1 antibody, pdha antibody, phe1a antibody, pdhce1a antibody, im:6895726 antibody, pdha1 antibody, wu:fd18b01 antibody, wu:fo96f03 antibody, zgc:73271 antibody, zgc:86692 antibody, Pdha1 antibody, wu:fp73b04 antibody, zgc:92705 antibody, NI36_05250 antibody, pdha1-a antibody, pdha1-b antibody, pyruvate dehydrogenase E1 alpha 1 subunit antibody, pyruvate dehydrogenase E1 alpha 1 antibody, pyruvate dehydrogenase (lipoamide) alpha 1 antibody, pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene antibody, 2-oxo acid dehydrogenase antibody, pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha antibody, pyruvate dehydrogenase alpha subunit protein antibody, pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit antibody, precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit antibody, pyruvate dehydrogenase antibody, pyruvate dehydrogenase E1 alpha 1 subunit a antibody, pyruvate dehydrogenase E1 alpha 1 subunit b antibody, pyruvate dehydrogenase E1 component subunit alpha antibody, pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog antibody, PDHA1 antibody, Pdha1 antibody, pdha1 antibody, LOC719277 antibody, VNG_RS07485 antibody, RR_RS04695 antibody, pdhA1 antibody, pdha1a antibody, pdha1b antibody, NI36_RS05240 antibody, pdha1.S antibody
    Background
    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 45 kDa

    Calculated_MW: 40 kDa/43 kDa/44 kDa/47 kDa

    Gene ID
    5160
    UniProt
    P08559
    Pathways
    Warburg Effect
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