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TMEM106B antibody (AA 218-252)

TMEM106B Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal RB56763 unconjugated
Catalog No. ABIN6244143
  • Target See all TMEM106B Antibodies
    TMEM106B (Transmembrane Protein 106B (TMEM106B))
    Binding Specificity
    • 15
    • 2
    • 2
    • 1
    AA 218-252
    Reactivity
    • 22
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 21
    • 1
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMEM106B antibody is un-conjugated
    Application
    • 22
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Predicted Reactivity
    B, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TMEM106B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 218-252 amino acids from human TMEM106B.
    Clone
    RB56763
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:2000. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Jiang, Cao, Sawaya, Abskharon, Ge, DeTure, Dickson, Fu, Ogorzalek Loo, Loo, Eisenberg: "Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43." in: Nature, Vol. 605, Issue 7909, pp. 304-309, (2022) (PubMed).

  • Target
    TMEM106B (Transmembrane Protein 106B (TMEM106B))
    Alternative Name
    TMEM106B (TMEM106B Products)
    Synonyms
    2310036D22Rik antibody, 5830455K21Rik antibody, 6430519M21Rik antibody, AI428776 antibody, AI661344 antibody, LRRGT00101 antibody, MGC81788 antibody, tmem106b antibody, zgc:114147 antibody, zgc:64013 antibody, transmembrane protein 106B antibody, transmembrane protein 106B S homeolog antibody, transmembrane protein 106Bb antibody, transmembrane protein 106b antibody, transmembrane protein 106Ba antibody, TMEM106B antibody, Tmem106b antibody, tmem106b.S antibody, tmem106b antibody, tmem106bb antibody, Tsp_02056 antibody, Tsp_01553 antibody, t106b antibody, tmem106ba antibody
    Background
    Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.
    Molecular Weight
    31127
    UniProt
    Q9NUM4
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