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PRKAB1 antibody

PRKAB1 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7269654
  • Target See all PRKAB1 Antibodies
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    Reactivity
    • 115
    • 100
    • 97
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 137
    • 9
    Rabbit
    Clonality
    • 129
    • 17
    Monoclonal
    Conjugate
    • 52
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    This PRKAB1 antibody is un-conjugated
    Application
    • 81
    • 65
    • 65
    • 48
    • 28
    • 22
    • 15
    • 15
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purpose
    AMPKβ1 Rabbit mAb
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human AMPKbeta1
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    Alternative Name
    PRKAB1 (PRKAB1 Products)
    Synonyms
    AMPK antibody, HAMPKb antibody, 1300015D22Rik antibody, AU021155 antibody, E430008F22 antibody, MGC82489 antibody, prkab1 antibody, wu:fk93d05 antibody, wu:fw87e09 antibody, zgc:56652 antibody, zgc:76975 antibody, zgc:92228 antibody, protein kinase AMP-activated non-catalytic subunit beta 1 antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, b antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, a antibody, PRKAB1 antibody, Prkab1 antibody, prkab1.S antibody, prkab1 antibody, prkab1b antibody, prkab1a antibody
    Background
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008],AMPK, HAMPKb,AMPK Signaling Pathway,Autophagy,Autophagy_Regulator,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Kinase,Kinase_Serine/threonine kinases,Lipid Metabolism,Lipids,Lipids_Fatty Acids,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Regulator of mTOR complex function,Protein phosphorylation,Signal Transduction,Warburg Effect,PRKAB1
    Molecular Weight
    38kDa
    Gene ID
    5564
    UniProt
    Q9Y478
    Pathways
    AMPK Signaling, Warburg Effect
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