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PCDHA3 antibody (C-Term)

PCDHA3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB31606 unconjugated
Catalog No. ABIN656078
  • Target See all PCDHA3 Antibodies
    PCDHA3 (Protocadherin alpha 3 (PCDHA3))
    Binding Specificity
    • 7
    • 7
    • 7
    • 3
    • 1
    • 1
    AA 773-800, C-Term
    Reactivity
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This PCDHA3 antibody is un-conjugated
    Application
    • 21
    • 16
    • 16
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PCDHA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-800 amino acids from the C-terminal region of human PCDHA3.
    Clone
    RB31606
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PCDHA3 (Protocadherin alpha 3 (PCDHA3))
    Alternative Name
    PCDHA3 (PCDHA3 Products)
    Synonyms
    PCDH-ALPHA3 antibody, mKIAA0345 antibody, PCDHA2 antibody, PCDHA3 antibody, PCDHA4 antibody, Pcdha3 antibody, protocadherin alpha 3 antibody, protocadherin alpha-3 antibody, PCDHA3 antibody, Pcdha3 antibody, pcdha3 antibody, LOC100713314 antibody
    Background
    This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Molecular Weight
    102428
    Gene ID
    56145
    NCBI Accession
    NP_061729, NP_113685
    UniProt
    Q9Y5H8
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