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SMURF1 antibody (AA 165-268)

SMURF1 Reactivity: Human WB, ELISA, IHC (p), IF, IP Host: Mouse Monoclonal 1D7 unconjugated
Catalog No. ABIN566098
  • Target See all SMURF1 Antibodies
    SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
    Binding Specificity
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 165-268
    Reactivity
    • 47
    • 23
    • 3
    Human
    Host
    • 44
    • 3
    Mouse
    Clonality
    • 45
    • 2
    Monoclonal
    Conjugate
    • 22
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMURF1 antibody is un-conjugated
    Application
    • 37
    • 28
    • 18
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant SMURF1.
    Sequence
    DSGPGRPLSC FMEEPAPYTD STGAAAGGGN CRFVESPSQD QRLQAQRLRN PDVRGSLQTP QNRPHGHQSP ELPEGYEQRT TVQGQVYFLH TQTGVSTWHD PRIP
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    SMURF1 (NP_065162, 165 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1D7
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).

    Murakami, Mathew, Huang, Farahani, Peng, Olson, Etlinger: "Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 7, pp. 805-13, (2010) (PubMed).

  • Target
    SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
    Alternative Name
    SMURF1 (SMURF1 Products)
    Synonyms
    4930431E10Rik antibody, mKIAA1625 antibody, RGD1309707 antibody, SMAD specific E3 ubiquitin protein ligase 1 antibody, E3 ubiquitin-protein ligase SMURF1 antibody, SMAD specific E3 ubiquitin protein ligase 1 L homeolog antibody, SMURF1 antibody, LOC100540915 antibody, smurf1 antibody, Smurf1 antibody, smurf1.L antibody
    Background
    Full Gene Name: SMAD specific E3 ubiquitin protein ligase 1
    Synonyms: KIAA1625
    Gene ID
    57154
    NCBI Accession
    NM_020429
    Pathways
    Regulation of Cell Size
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