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ZC3H8 antibody (Internal Region)

ZC3H8 Reactivity: Human, Mouse WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258445
  • Target See all ZC3H8 Antibodies
    ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 37
    • 27
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 50
    • 2
    Rabbit
    Clonality
    • 50
    • 2
    Polyclonal
    Conjugate
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZC3H8 antibody is un-conjugated
    Application
    • 29
    • 19
    • 13
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    ZC3H8 Antibody detects endogenous levels of total ZC3H8.
    Predicted Reactivity
    Pig,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ZC3H8, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ZC3H8 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
    Alternative Name
    ZC3H8 (ZC3H8 Products)
    Synonyms
    Zc3hdc8 antibody, DKFZp459D018 antibody, AU020882 antibody, E130108N08Rik antibody, Fliz1 antibody, ZC3HDC8 antibody, zinc finger CCCH type containing 8 antibody, zinc finger CCCH-type containing 8 antibody, Zc3h8 antibody, ZC3H8 antibody
    Background

    Description: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

    Gene: ZC3H8

    Molecular Weight
    40 kDa
    Gene ID
    84524
    UniProt
    Q8N5P1
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