ZC3H8 antibody (Internal Region)
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- Target See all ZC3H8 Antibodies
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZC3H8 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- ZC3H8 Antibody detects endogenous levels of total ZC3H8.
- Predicted Reactivity
- Pig,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ZC3H8, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ZC3H8 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
- Alternative Name
- ZC3H8 (ZC3H8 Products)
- Synonyms
- Zc3hdc8 antibody, DKFZp459D018 antibody, AU020882 antibody, E130108N08Rik antibody, Fliz1 antibody, ZC3HDC8 antibody, zinc finger CCCH type containing 8 antibody, zinc finger CCCH-type containing 8 antibody, Zc3h8 antibody, ZC3H8 antibody
- Background
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Description: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Gene: ZC3H8
- Molecular Weight
- 40 kDa
- Gene ID
- 84524
- UniProt
- Q8N5P1
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