MICAL1 antibody (AA 806-1067)
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- Target See all MICAL1 Antibodies
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
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Binding Specificity
- AA 806-1067
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MICAL1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human [F-actin]-methionine sulfoxide oxidase MICAL1 protein (806-1067AA)
- Isotype
- IgG
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anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) (AA 971-1067) antibody
MICAL1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3D12 unconjugated
anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) (Internal Region) antibodyMICAL1 Reactivity: Human, Mouse WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) (AA 1-981) antibodyMICAL1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) (C-Term) antibodyMICAL1 Reactivity: Human, Pig, Rabbit, Cow, Dog, Horse, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) (AA 718-1067) antibodyMICAL1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
- Alternative Name
- MICAL1 (MICAL1 Products)
- Synonyms
- MICAL antibody, MICAL-1 antibody, NICAL antibody, Nical antibody, zgc:171928 antibody, microtubule associated monooxygenase, calponin and LIM domain containing 1 antibody, MICAL1 antibody, Mical1 antibody, mical1 antibody
- Background
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Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L, acts by antagonizing STK38 and STK38L activation by MST1/STK4. Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections. Through redox regulation of the actin cytoskeleton controls the intracellular distribution of sectrory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels (By similarity). May act as Rab effector protein and play a role in vesicle trafficking.
Aliases: CasL interacting molecule antibody, DKFZp434B1517 antibody, FLJ11937 antibody, FLJ21739 antibody, MICA1_HUMAN antibody, MICAL 1 antibody, MICAL antibody, MICAL1 antibody, microtubule associated monoxygenase, calponin and LIM domain containing 1 antibody, Molecule interacting with CasL protein 1 antibody, NEDD9 interacting protein with calponin homology and LIM domains antibody, NEDD9-interacting protein with calponin homology and LIM domains antibody, NICAL antibody, OTTHUMP00000016969 antibody
- UniProt
- Q8TDZ2
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