TBC1D23 antibody (Internal Region)
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- Target See all TBC1D23 products
- TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TBC1D23 antibody is un-conjugated
- Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- TBC1D23 Antibody detects endogenous levels of total TBC1D23.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TBC1D23, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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anti-TBC1 Domain Family, Member 23 (TBC1D23) (AA 510-605) antibody
TBC1D23 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-TBC1 Domain Family, Member 23 (TBC1D23) (AA 250-600) antibodyTBC1D23 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-TBC1 Domain Family, Member 23 (TBC1D23) (C-Term) antibodyTBC1D23 Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
- Alternative Name
- TBC1D23 (TBC1D23 Products)
- Synonyms
- RGD1307925 antibody, NS4ATP1 antibody, 4930451A13Rik antibody, AU015720 antibody, AU043671 antibody, AU043778 antibody, D030022P07Rik antibody, W51689 antibody, zgc:63756 antibody, TBC1 domain family, member 23 antibody, TBC1 domain family member 23 antibody, Tbc1d23 antibody, TBC1D23 antibody, tbc1d23 antibody
- Background
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Description: Putative Rab GTPase-activating protein which plays a role in vesicular trafficking (PubMed:28823707). Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (PubMed:29084197). Plays a role in brain development, including in cortical neuron positioning (By similarity). May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).
Gene: TBC1D23
- Molecular Weight
- 78 kDa
- Gene ID
- 55773
- UniProt
- Q9NUY8
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