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Acylglycerol Kinase antibody (C-Term)

Name: Acylglycerol Kinase antibody (C-Term)
SKU: ABIN6259823
Price: 390.77 USD
Availability: InStock

AGK Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

Western blot analysis of AGK using Jurkat whole cell lysates (Acylglycerol Kinase antibody (C-Term))

ABIN6278749 at 1/100 staining Human brain cancer tissue by IHC-P. (Acylglycerol Kinase antibody (C-Term))

IHC

2 images

Catalog No. ABIN6259823

Datasheet as PDF

Target See all Acylglycerol Kinase (AGK) Antibodies

Acylglycerol Kinase (AGK)
Binding Specificity
6

2

1

1

1

1

1

1

1

1
C-Term
Reactivity
26

15

5

3

3

3

2

2

2

1

1

1
Human, Mouse
Host
23

3

1
Rabbit
Compatible Secondaries
Clonality
26

1
Polyclonal
Conjugate
16

2

2

1

1

1

1

1

1

1
This Acylglycerol Kinase antibody is un-conjugated
Application
16

8

4

2

2

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity

AGK Antibody detects endogenous levels of total AGK.

Predicted Reactivity

Bovine,Dog,Chicken

Purification

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human AGK, corresponding to a region within C-terminal amino acids.

Isotype

IgG

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anti-Acylglycerol Kinase (AGK) (AA 32-65) antibody
AGK Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (AA 35-84) antibody
AGK Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Hamster, Bat, Pig WB Host: Rabbit Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (AA 15-300) antibody
AGK Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) antibody
AGK Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (AA 335-422) antibody
AGK Reactivity: Mouse WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (C-Term) antibody
Verified AGK Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (AA 1-422) antibody
AGK Reactivity: Human WB Host: Mouse Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (AA 107-156) antibody
AGK Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Hamster, Monkey WB Host: Rabbit Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (AA 233-422) antibody
AGK Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Acylglycerol Kinase (AGK) (AA 32-65) antibody (HRP)
AGK Reactivity: Human ELISA Host: Rabbit Polyclonal HRP

Application Notes

WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date

12 months
Target

Acylglycerol Kinase (AGK)

Alternative Name

AGK (AGK Products)

Synonyms

mulk antibody, CATC5 antibody, CTRCT38 antibody, MTDPS10 antibody, MULK antibody, 2610037M15Rik antibody, 6720408I04Rik antibody, AI465370 antibody, Mulk antibody, RGD1562046 antibody, fi38e09 antibody, wu:fi38e09 antibody, zgc:55462 antibody, acylglycerol kinase antibody, acylglycerol kinase S homeolog antibody, AGK antibody, agk antibody, LOC100165096 antibody, Agk antibody, agk.S antibody

Background

Description: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively (PubMed:15939762). Does not phosphorylate sphingosine (PubMed:15939762). Independently of its lipid kinase activity, acts as a component of the TIM22 complex (PubMed:28712724, PubMed:28712726). The TIM22 complex mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane by forming a twin-pore translocase that uses the membrane potential as the external driving force (PubMed:28712724, PubMed:28712726). In the TIM22 complex, required for the import of a subset of metabolite carriers into mitochtondria, such as ANT1/SLC25A4 and SLC25A24, while it is not required for the import of TIMM23 (PubMed:28712724). Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth (PubMed:15939762).
Gene: AGK

Molecular Weight

47 kDa

Gene ID

55750

UniProt

Q53H12