ACTC1 antibody
(4 references)-
- Target See all ACTC1 Antibodies
- ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ACTC1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit Polyclonal antibody to alpha Cardiac Muscle Actin (actin, alpha, cardiac muscle 1)
alpha Cardiac Muscle Actin antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human alpha Cardiac Muscle Actin. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) (AA 156-368) antibody
ACTC1 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C7 unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) (N-Term) antibodyACTC1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) antibodyACTC1 Reactivity: Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) (AA 156-368) antibodyACTC1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) antibodyACTC1 Reactivity: Human, Rat, Rabbit, Pig, Goat WB, ELISA, IHC, IHC (fro) Host: Mouse Monoclonal 22D3 unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) (AA 156-368) antibodyACTC1 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) antibodyACTC1 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) (N-Term) antibodyACTC1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Monoclonal RM257 unconjugated
anti-Actin, Alpha, Cardiac Muscle 1 (ACTC1) (N-Term) antibodyACTC1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: PC-12 , Rat2 , Jurkat , Raji , K562 , THP-1 , NIH-3T3 , JC , BCL-1 , Rat muscle
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.56 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "RYBP is important for cardiac progenitor cell development and sarcomere formation." in: PLoS ONE, Vol. 15, Issue 7, pp. e0235922, (2020) (PubMed).
: "Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential." in: Stem cells and development, Vol. 28, Issue 9, pp. 593-607, (2020) (PubMed).
: "Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells." in: International journal of molecular sciences, Vol. 21, Issue 14, (2020) (PubMed).
: "Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells." in: Frontiers in physiology, Vol. 8, pp. 336, (2017) (PubMed).
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: "RYBP is important for cardiac progenitor cell development and sarcomere formation." in: PLoS ONE, Vol. 15, Issue 7, pp. e0235922, (2020) (PubMed).
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- Target
- ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))
- Alternative Name
- actin alpha cardiac muscle 1 (ACTC1 Products)
- Synonyms
- acta1 antibody, actc antibody, fa27h01 antibody, fb83f06 antibody, wu:fa27h01 antibody, wu:fb83f06 antibody, ACTC antibody, ASD5 antibody, CMD1R antibody, CMH11 antibody, LVNC4 antibody, Actc-1 antibody, actcl antibody, actc1l antibody, cmd1r antibody, ACTC1 antibody, actin, alpha, cardiac muscle 1 L homeolog antibody, actin, alpha, cardiac muscle 1b antibody, actin, alpha, cardiac muscle 1 antibody, actin, alpha, cardiac muscle 1a antibody, actc1.L antibody, actc1b antibody, ACTC1 antibody, Actc1 antibody, actc1a antibody, actc1 antibody
- Background
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Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
Cellular Localization: Cytoplasm , cytoskeleton - Molecular Weight
- 42 kDa
- Gene ID
- 70
- UniProt
- P68032
- Pathways
- Myometrial Relaxation and Contraction
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