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WNT11 antibody (Center)

WNT11 Reactivity: Human, Mouse WB, IHC, ICC, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856232
  • Target See all WNT11 Antibodies
    WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))
    Binding Specificity
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 19
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 18
    • 2
    • 2
    Rabbit
    Clonality
    • 18
    • 4
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNT11 antibody is un-conjugated
    Application
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Cross-Reactivity
    Chicken, Rat (Rattus), Xenopus laevis, Cow (Bovine)
    Cross-Reactivity (Details)
    Chicken (85 %), Rat (96 %), Xenopus laevis (81 %), Bovine (98 %)
    Characteristics
    Rabbit Polyclonal antibody to WNT11 (wingless-type MMTV integration site family, member 11)
    WNT11 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human WNT11. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: 293T , A431 , HeLa , HepG2 , mouse heart

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Glaeser, Urban, Fenech, Voloshanenko, Kranz, Lari, Christianson, Boutros: "ERAD-dependent control of the Wnt secretory factor Evi." in: The EMBO journal, Vol. 37, Issue 4, (2018) (PubMed).

    Jain, Noordam, Hoshi, Vallania, Conrad: "Validating single-cell genomics for the study of renal development." in: Kidney international, Vol. 86, Issue 5, pp. 1049-55, (2015) (PubMed).

  • Target
    WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))
    Alternative Name
    WNT11 (WNT11 Products)
    Synonyms
    HWNT11 antibody, Wnt11r antibody, Xwnt11 antibody, Xwnt-11 antibody, wnt11-r antibody, XWnt-11 antibody, wnt11b antibody, wnt11b-2 antibody, Slb/Wnt11 antibody, cb748 antibody, slb antibody, Wnt12 antibody, WNT11 antibody, wnt-11 antibody, xwnt11 antibody, Wnt family member 11 antibody, wingless-type MMTV integration site family member 11 L homeolog antibody, wingless-type MMTV integration site family, member 11B antibody, wingless-type MMTV integration site family, member 11 antibody, protein Wnt-11-like antibody, wingless-type MMTV integration site family, member 10B antibody, wingless-type MMTV integration site family, member 11B L homeolog antibody, WNT11 antibody, Wnt11 antibody, wnt11.L antibody, wnt11b antibody, wnt11 antibody, LOC100229189 antibody, Wnt10b antibody, wnt11b.L antibody
    Background
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97 % , 85 %, and 63 % amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    Molecular Weight
    39 kDa
    Gene ID
    7481
    Pathways
    WNT Signaling, Cell-Cell Junction Organization
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