Importin 4 antibody (AA 728-1081)
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- Target See all Importin 4 (IPO4) Antibodies
- Importin 4 (IPO4)
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Binding Specificity
- AA 728-1081
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Importin 4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purpose
- IPO4 Rabbit pAb
- Sequence
- LHKACQSCPS EPNTAALQAA LARVVPSYMQ AVNRERERQV VMAVLEALTG VLRSCGTLTL KPPGRLAELC GVLKAVLQRK TACQDTDEEE EEEDDDQAEY DAMLLEHAGE AIPALAAAAG GDSFAPFFAG FLPLLVCKTK QGCTVAEKSF AVGTLAETIQ GLGAASAQFV SRLLPVLLST AQEADPEVRS NAIFGMGVLA EHGGHPAQEH FPKLLGLLFP LLARERHDRV RDNICGALAR LLMASPTRKP EPQVLAALLH ALPLKEDLEE WVTIGRLFSF LYQSSPDQVI DVAPELLRIC SLILADNKIP PDTKAALLLL LTFLAKQHTD SFQAALGSLP VDKAQELQAV LGLS
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 728-1081 of human IPO4 (NP_078934.3).
- Isotype
- IgG
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anti-Importin 4 (IPO4) (Internal Region) antibody
IPO4 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Importin 4 (IPO4) antibodyIPO4 Reactivity: Human, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Importin 4 (IPO4) antibodyIPO4 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
anti-Importin 4 (IPO4) (AA 468-517) antibodyIPO4 Reactivity: Human, Dog, Guinea Pig, Horse, Bat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Importin 4 (IPO4)
- Alternative Name
- IPO4 (IPO4 Products)
- Synonyms
- Imp4 antibody, 8430408O15Rik antibody, AA409693 antibody, Imp4a antibody, RanBP4 antibody, importin 4 antibody, IPO4 antibody, Ipo4 antibody
- Background
- Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity. Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.,IPO4,Imp4,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,IPO4
- Molecular Weight
- 119kDa
- Gene ID
- 79711
- UniProt
- Q8TEX9
- Pathways
- Protein targeting to Nucleus
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