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PREX2 antibody (AA 1417-1592)

DEPDC2 Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7163181
  • Target See all PREX2 (DEPDC2) Antibodies
    PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 1417-1592
    Reactivity
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 11
    • 2
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 7
    • 3
    • 2
    • 1
    This PREX2 antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (1417-1592AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))
    Alternative Name
    PREX2 (DEPDC2 Products)
    Synonyms
    6230420N16Rik antibody, DEP.2 antibody, DEPDC2 antibody, P-REX2 antibody, AI316880 antibody, AI553603 antibody, C030045D06Rik antibody, D430013K02 antibody, Depdc2 antibody, P-Rex2 antibody, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 antibody, PREX2 antibody, Prex2 antibody
    Background

    Background: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

    Aliases: 4 antibody, 5)-dependent Rac exchanger 2 antibody, 5-trisphosphate-dependent Rac exchanger 2 protein antibody, 6230420N16Rik antibody, DEP domain-containing protein 2 antibody, DEP.2 antibody, DEPDC2 antibody, FLJ12987 antibody, P-Rex2 antibody, Phosphatidylinositol 3 antibody, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 antibody, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 antibody, PREX2 antibody, PREX2_HUMAN antibody, PtdIns(3 antibody, PtdIns(3,4,5)-dependent Rac exchanger 2 antibody

    UniProt
    Q70Z35
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