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Transmembrane 7 Superfamily Member 4 (TM7SF4) (AA 119-209) antibody

TM7SF4 Reactivity: Human ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7149663
  • Target See all Transmembrane 7 Superfamily Member 4 (TM7SF4) Antibodies
    Transmembrane 7 Superfamily Member 4 (TM7SF4)
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    AA 119-209
    Reactivity
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Dendritic cell-specific transmembrane protein (119-209AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Transmembrane 7 Superfamily Member 4 (TM7SF4)
    Alternative Name
    DCSTAMP (TM7SF4 Products)
    Synonyms
    Tm7sf4 antibody, TM7SF4 antibody, FIND antibody, hDC-STAMP antibody, 4833414I07Rik antibody, DC-STAMP antibody, mDC-STAMP antibody, dendrocyte expressed seven transmembrane protein antibody, Dcstamp antibody, DCSTAMP antibody
    Background

    Background: Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

    Aliases: DC-STAMP antibody, DCSTAMP antibody, DCSTP_HUMAN antibody, Dendritic cell-specific transmembrane protein antibody, Dendrocyte-expressed seven transmembrane protein antibody, FIND antibody, hDC-STAMP antibody, IL-Four INDuced antibody, IL-four-induced protein antibody, Transmembrane 7 superfamily member 4 antibody

    UniProt
    Q9H295
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