Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SUV420H2/KMT5C antibody (AA 187-214)

SUV420H2 Reactivity: Mouse, Human WB, FACS Host: Rabbit Polyclonal RB19392 unconjugated
Catalog No. ABIN390405
  • Target See all SUV420H2/KMT5C (SUV420H2) Antibodies
    SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))
    Binding Specificity
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 187-214
    Reactivity
    • 14
    • 13
    • 2
    • 1
    • 1
    • 1
    Mouse, Human
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 20
    • 1
    • 1
    Polyclonal
    Conjugate
    • 13
    • 4
    • 3
    • 1
    • 1
    This SUV420H2/KMT5C antibody is un-conjugated
    Application
    • 17
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Predicted Reactivity
    Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids of human SUV4-20H2.
    Clone
    RB19392
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SUV420H2 Primary Antibody
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Boonsanay, Zhang, Georgieva, Kostin, Qi, Yuan, Zhou, Braun: "Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation." in: Cell stem cell, Vol. 18, Issue 2, pp. 229-42, (2016) (PubMed).

  • Target
    SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))
    Alternative Name
    SUV4-20H2 (SUV420H2 Products)
    Synonyms
    zgc:162876 antibody, KMT5C antibody, BC024816 antibody, Suv4-20h2 antibody, lysine methyltransferase 5C antibody, suppressor of variegation 4-20 homolog 2 (Drosophila) antibody, lysine (K)-specific methyltransferase 5C L homeolog antibody, KMT5C antibody, kmt5c antibody, SUV420H2 antibody, kmt5c.L antibody, Kmt5c antibody
    Background
    SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
    Molecular Weight
    52113
    Gene ID
    84787
    NCBI Accession
    NP_116090
    UniProt
    Q86Y97
You are here:
Support