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SUCLG1 antibody

KO Validated SUCLG1 Reactivity: Human WB, IF, IP, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856658
  • Target See all SUCLG1 Antibodies
    SUCLG1 (Succinate-CoA Ligase, alpha Subunit (SUCLG1))
    Reactivity
    • 19
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 20
    • 1
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 17
    • 2
    • 1
    • 1
    This SUCLG1 antibody is un-conjugated
    Application
    • 16
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Knockdown/Knockout validation was supported by references (PMID:26990993)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to SUCLG1 (succinate-CoA ligase, alpha subunit)
    SUCLG1 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Full length human SUCLG1 Recombinant protein.
    Isotype
    IgG
  • Application Notes
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Rat brain , Mouse brain

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.48 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    SUCLG1 (Succinate-CoA Ligase, alpha Subunit (SUCLG1))
    Alternative Name
    succinate-CoA ligase alpha subunit (SUCLG1 Products)
    Synonyms
    galpha antibody, mtdps9 antibody, sucla1 antibody, GALPHA antibody, MTDPS9 antibody, SUCLA1 antibody, SCS antibody, zgc:103729 antibody, zgc:92738 antibody, 1500000I01Rik antibody, Sucla1 antibody, succinate-CoA ligase alpha subunit antibody, succinate-CoA ligase, alpha subunit L homeolog antibody, succinate-CoA ligase, alpha subunit antibody, succinate-CoA ligase, GDP-forming, alpha subunit antibody, SUCLG1 antibody, suclg1.L antibody, suclg1 antibody, Suclg1 antibody
    Background
    This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.

    Cellular Localization: Mitochondrion
    Molecular Weight
    36 kDa
    Gene ID
    8802
    UniProt
    P53597
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