TIFA antibody (N-Term)
TIFA
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB24815
unconjugated
-
- Target See all TIFA Antibodies
- TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
-
Binding Specificity
- AA 52-79, N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TIFA antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TIFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-79 amino acids from the N-terminal region of human TIFA.
- Clone
- RB24815
- Isotype
- Ig Fraction
-
-
- Application Notes
- WB: 1:2000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
-
- Target
- TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
- Alternative Name
- TIFA (TIFA Products)
- Synonyms
- TIFA antibody, xtifa antibody, T2BP antibody, T6BP antibody, TIFAA antibody, T2bp antibody, Ab2-389 antibody, TRAF interacting protein with forkhead associated domain antibody, TRAF-interacting protein with forkhead-associated domain antibody, TRAF-interacting protein with forkhead-associated domain S homeolog antibody, TIFA antibody, tifa antibody, Tifa antibody, tifa.S antibody
- Background
- Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
- Molecular Weight
- 21445
- Gene ID
- 92610
- NCBI Accession
- NP_443096
- UniProt
- Q96CG3
-
You are here:
