TP53INP1 antibody
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- Target See all TP53INP1 Antibodies
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This TP53INP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purpose
- p53 DINP1 Rabbit mAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human p53 DINP1
- Isotype
- IgG
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anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 36-64), (N-Term) antibody
TP53INP1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB29674 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 181-210), (C-Term) antibodyTP53INP1 Reactivity: Mouse WB, IHC (p) Host: Rabbit Polyclonal RB29563 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibodyTP53INP1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 138-205) antibodyTP53INP1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (Internal Region) antibodyTP53INP1 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (N-Term) antibodyTP53INP1 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibodyTP53INP1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 1-100) antibodyTP53INP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibodyTP53INP1 Reactivity: Human, Monkey WB, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 43-72), (N-Term) antibodyTP53INP1 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
- Alternative Name
- TP53INP1 (TP53INP1 Products)
- Synonyms
- cb1036 antibody, wu:fb70a09 antibody, wu:fi13h08 antibody, zgc:158431 antibody, TP53INP1 antibody, 2700057G22Rik antibody, SIP antibody, SIP18 antibody, SIP27 antibody, Stinp antibody, Teap antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, p53DINP1 antibody, Trp53inp1 antibody, tumor protein p53 inducible nuclear protein 1 antibody, tumor protein p53 inducible nuclear protein 1 S homeolog antibody, transformation related protein 53 inducible nuclear protein 1 antibody, TP53INP1 antibody, tp53inp1.S antibody, tp53inp1 antibody, Trp53inp1 antibody, Tp53inp1 antibody
- Background
- Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.,SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1,Apoptosis,Autophagy,Cancer,Cell Biology & Developmental Biology,Tumor suppressors,Tumor suppressors_p53 pathway,TP53INP1
- Molecular Weight
- 32kDa
- Gene ID
- 94241
- UniProt
- Q96A56
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