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NCOR1 antibody (AA 1-200)

NCOR1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6144420
  • Target See all NCOR1 Antibodies
    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200
    Reactivity
    • 50
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 50
    • 1
    Polyclonal
    Conjugate
    • 28
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCOR1 antibody is un-conjugated
    Application
    • 28
    • 23
    • 18
    • 13
    • 13
    • 10
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    MSSSGYPPNQ GAFSTEQSRY PPHSVQYTFP NTRHQQEFAV PDYRSSHLEV SQASQLLQQQ QQQQLRRRPS LLSEFHPGSD RPQERRTSYE PFHPGPSPVD HDSLESKRPR LEQVSDSHFQ RVSAAVLPLV HPLPEGLRAS ADAKKDPAFG GKHEAPSSPI SGQPCGDDQN ASPSKLSKEE LIQSMDRVDR EIAKVEQQIL
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NCOR1 (NP_006302.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
    Alternative Name
    NCOR1 (NCOR1 Products)
    Synonyms
    ncor antibody, zgc:56355 antibody, 5730405M06Rik antibody, A230020K14Rik antibody, N-CoR antibody, RIP13 antibody, Rxrip13 antibody, mKIAA1047 antibody, N-CoR1 antibody, TRAC1 antibody, hN-CoR antibody, nuclear receptor corepressor 1 antibody, nuclear receptor co-repressor 1 antibody, nuclear receptor corepressor 1 pseudogene antibody, nuclear receptor corepressor 1 S homeolog antibody, ncor1 antibody, NCOR1 antibody, CpipJ_CPIJ002507 antibody, LOC100343278 antibody, Ncor1 antibody, ncor1.S antibody
    Background
    This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.,NCOR1,N-CoR,N-CoR1,PPP1R109,TRAC1,hN-CoR,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,NCOR1
    Molecular Weight
    103 kDa/258 kDa/270 kDa
    Gene ID
    9611
    UniProt
    O75376
    Pathways
    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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