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GAB2 antibody (AA 273-484)

GAB2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7154436
  • Target See all GAB2 Antibodies
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Binding Specificity
    • 25
    • 17
    • 16
    • 11
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 273-484
    Reactivity
    • 120
    • 92
    • 86
    • 4
    • 4
    • 4
    • 2
    Human
    Host
    • 119
    • 1
    • 1
    Rabbit
    Clonality
    • 121
    Polyclonal
    Conjugate
    • 42
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAB2 antibody is un-conjugated
    Application
    • 89
    • 41
    • 39
    • 39
    • 20
    • 15
    • 13
    • 9
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human GRB2-associated-binding protein 2 protein (273-484AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Alternative Name
    GAB2 (GAB2 Products)
    Synonyms
    GAB2 antibody, AI463667 antibody, D130058I17Rik antibody, p97 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GAB2 antibody, gab2 antibody, Gab2 antibody
    Background

    Background: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

    Aliases: GAB 2 antibody, Gab2 antibody, GAB2_HUMAN antibody, Grb 2 associated binder 2 antibody, GRB 2 associated binding protein 2 antibody, Grb2 associated binder 2 antibody, GRB2 associated binder 2 pp100 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binder 2 antibody, GRB2-associated-binding protein 2 antibody, Growth factor receptor bound protein 2 associated protein 2 antibody, Growth factor receptor bound protein 2-associated protein 2 antibody, KIAA0571 antibody, p97 antibody, PH domain containing adaptor molecule p97 antibody, pp100 antibody

    UniProt
    Q9UQC2
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
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