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Browse our anti-PTEN (PTEN) Antibodies

Full name:
anti-Phosphatase and Tensin Homolog Antibodies (PTEN)
On www.antibodies-online.com are 0 Phosphatase and Tensin Homolog (PTEN) Antibodies from different suppliers available. A total of 0 PTEN products are currently listed.
Synonyms:
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
list all antibodies Gene Name GeneID UniProt
Anti-Mouse PTEN PTEN 19211 O08586
Anti-Rat PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

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More Antibodies against PTEN Interaction Partners

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. Inhibition of PLK1 (show PLK1 Antibodies) activity or overexpression of a non-phosphorylatable PLK1 (show PLK1 Antibodies) mutant reduces the polyploid cell population.

  2. These findings demonstrate an important role for Pten in maintenance of airway epithelial phenotype integrity.

  3. Data indicate that hydrogen sulfide (show SQRDL Antibodies) H(2)S inhibits Abeta (show APP Antibodies)-induced neuronal apoptosis by attenuating mitochondrial translocation of phosphatase and tensin (show TNS1 Antibodies) homologs deleted on chromosome 10 and that activation of PI3K/AKT (show AKT1 Antibodies) signaling pathway plays a critical role in H(2)S-mediated neuronal protection. Our findings provide a novel route into the molecular mechanisms of neuronal apoptosis in Alzheimer's disease.

  4. miR (show MLXIP Antibodies)-217inhibition can protectively antagonize high glucose-induced podocyte damage and insulin (show INS Antibodies) resistance by restoring the defective autophagy pathway via targeting PTEN

  5. that Pten, through the Dlg1 (show DLG1 Antibodies)-binding ability of its PDZ (show INADL Antibodies)-binding domain , accumulates phosphorylated Eg5 (show KIF11 Antibodies) at duplicated centrosomes to establish symmetrical bipolar spindles that properly segregate chromosomes

  6. PTEN mediates hepatic macrophage activation in liver fibrosis.

  7. miR (show MLXIP Antibodies)-718 modulates PI3K/Akt (show AKT1 Antibodies) signaling by directly down-regulating phosphatase and tensin homolog (PTEN), thereby promoting phosphorylation of Akt (show AKT1 Antibodies), which leads to a decrease in proinflammatory cytokine production.

  8. Downregulated miR (show MLXIP Antibodies)-152 induced impaired hepatic glycogenesis by targeting PTEN. PTEN participated in miR (show MLXIP Antibodies)-152-mediated glycogenesis in hepatocytes via regulation of the AKT (show AKT1 Antibodies)/GSK pathway

  9. The findings of this study suggest that deletion of Pten in the brain results in impaired bone mass and mineralization, which may contribute to weaker bones and thereby a higher fracture risk.

  10. phenotypic and genetic changes within the pre-neoplastic mammary epithelium of mice with and without stromal PTEN expression

Human Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. The miR (show MLXIP Antibodies)-19b-PTEN signaling pathway may serve as a novel therapeutic target in the context of ventilator-associated lung fibrosis.

  2. Results show that MiR (show MLXIP Antibodies)-20b binds to the 3'-UTR (show UTS2R Antibodies) of PTEN and their expression inversely correlates in esophageal cancer and cells.

  3. We show that the decrease in PI(4,5)P2 level under non-stimulated conditions inhibits PTEN activity leading to the aberrant activation of the oncoprotein Akt (show AKT1 Antibodies). As well as defining a novel mechanism of Akt (show AKT1 Antibodies) phosphorylation with important therapeutic consequences, we also demonstrate that differential expression levels of FGFR2 (show FGFR2 Antibodies), Plc11 and Grb2 (show GRB2 Antibodies) correlate with patient survival

  4. Inhibition of PLK1 (show PLK1 Antibodies) activity or overexpression of a non-phosphorylatable PLK1 (show PLK1 Antibodies) mutant reduces the polyploid cell population.

  5. In perspective of the crucial role PTEN plays in balancing proliferation and apoptosis, we propose PTEN as a valuable marker in the diagnosis, assessment of tumor grade, and disease stage in hepatocellular carcinoma patients

  6. PTEN nuclear expression increased with increasing mitotic rate in gastrointestinal stromal tumors.

  7. our findings demonstrated that dysregulation of miR (show MLXIP Antibodies)-19a plays critical roles in the osteosarcoma stem cells, at least in part via targeting the phosphatase and tensin homolog (PTEN) deleted on chromosome 10. Knockdown of miR (show MLXIP Antibodies)-19a may represent a potential strategy for the osteosarcoma treatment.

  8. our data suggest that microRNA-200c plays an oncogenic role in nasopharyngeal carcinoma by targeting PTEN

  9. Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer have been presented.

  10. we demonstrate that HOTAIR downregulates miR (show MLXIP Antibodies)-29b expression and attenuates its control on epigenetic regulation, leading to enhanced PTEN methylation, which contributes to the progression of liver fibrosis.

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN, FOXO3A (show FOXO3 Antibodies) and PKB (show AKT1 Antibodies) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. the miR-17-92 cluster is involved in granulosa cell proliferation and differentiation by coordinately targeting the PTEN and BMPR2 (show BMPR2 Antibodies) genes.

  2. miR (show MYLIP Antibodies)-26b participates in the inflammatory response of LPS (show IRF6 Antibodies)-stimulated bAMs by modulating the NF-kappaB (show NFKB1 Antibodies) pathway through targeting PTEN.

  3. Pten expression levels in the mammary glands of dairy cows, was investigated.

  4. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (show NOS3 Antibodies) activation in vascular endothelial cells.

  5. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  6. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (show DVL2 Antibodies).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen Profile

Antigen Summary

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) antibody
  • phosphatase and tensin homolog (PTEN) antibody
  • phosphatase and tensin homolog (pten) antibody
  • 10q23del antibody
  • 2310035O07Rik antibody
  • A130070J02Rik antibody
  • AI463227 antibody
  • B430203M17Rik antibody
  • BZS antibody
  • CWS1 antibody
  • DEC antibody
  • GLM2 antibody
  • MHAM antibody
  • Mmac antibody
  • MMAC1 antibody
  • PTEN1 antibody
  • PTENP1 antibody
  • TEP1 antibody

Protein level used designations for PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

GENE ID SPECIES
19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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