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Browse our anti-PTEN (PTEN) Antibodies

Full name:
anti-Phosphatase and Tensin Homolog Antibodies (PTEN)
On www.antibodies-online.com are 0 Phosphatase and Tensin Homolog (PTEN) Antibodies from different suppliers available. A total of 0 PTEN products are currently listed.
Synonyms:
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
list all antibodies Gene Name GeneID UniProt
Anti-Mouse PTEN PTEN 19211 O08586
Anti-Rat PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

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More Antibodies against PTEN Interaction Partners

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. We propose that targeted inhibition of PTEN and hyperactivation of AKT (show AKT1 Antibodies) triggers a checkpoint for the elimination of autoreactive B cells and represents a new strategy to overcome drug resistance in human pre-B acute lymphoblastic leukemia .

  2. Mutations in phosphatase and tensin homolog (PTEN) gene are also known to be associated with autism.

  3. In a transgenic breast cancer model, endogenous Pten suppression using a tetracycline-regulatable shRNA cooperates with human HER2/neu (show ERBB2 Antibodies), leading to aggressive and metastatic disease with elevated signaling through PI3K and, surprisingly, the MAPK (show MAPK1 Antibodies) pathway.

  4. PTEN is critically required for the development of a functional thymic epithelium in mice

  5. Study identifies crosstalk between PTEN and IRF3 (show IRF3 Antibodies) in tumor suppression and innate immunity.

  6. found that Abeta (show APP Antibodies)-induced synaptic and cognitive impairments are critically mediated by PTEN.

  7. activation of AKT (show AKT1 Antibodies) and mTORC1, the double knockout of PTEN and LKB1 (show STK11 Antibodies) contributes to distinct cell-specific aspects of tumor development and progression.

  8. ER stress caused dephosphorylation of PTEN, which was attenuated by Adh1 (show ADH1A Antibodies). ADH (show AVP Antibodies) protects against ER stress-induced cardiac anomalies possibly via attenuation of oxidative stress and PTEN/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway-regulated autophagy.

  9. isolated deletion of Pten failed to stimulate ectopic fiber cell differentiation, and the combined deletion of Pten and Fgfr2 (show FGFR2 Antibodies) failed to restore differentiation-specific Aquaporin0 and DnaseIIbeta expression in the lens fiber cells

  10. PTEN deficiency leads to the upregulation of PAX7 (show PAX7 Antibodies), which in turn promotes oncogenic transformation of neural stem cells.

Human Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. we demonstrate that PTEN protein expression is a significant indicator of prognosis in ovarian/peritoneal high-grade serous carcinoma

  2. Results identify PTEN as the substrate of AIF (show AIFM1 Antibodies) oxidoreductase (show TXNRD1 Antibodies) and reveal a novel function for AIF (show AIFM1 Antibodies) in controlling tumor metastasis.

  3. miR (show MLXIP Antibodies)-21 has a role in upregulating PTEN, RECK (show RECK Antibodies) and PDCD4 (show PDCD4 Antibodies) in glioma

  4. Combinatorial immunophenotypic analyses showed that loss of PTEN expression with concomitant IGFR-1 expression correlated with poor disease-free survival

  5. The impact of PTEN loss on tumor biology and clinical outcomes must be interpreted in the context of body mass index.

  6. ectopically expressed miR-17, miR (show MLXIP Antibodies)-20a and miR (show MLXIP Antibodies)-106b directly target PTEN 3'UTR (show UTS2R Antibodies) to reduce its expression, an effect rescued upon treatment with resveratrol and pterostilbene

  7. Glioma cell VEGFR-2 (show KDR Antibodies) confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma.

  8. the down-regulation of NDRG2 (show NDRG2 Antibodies) expression promotes the inactive phosphorylated form of PTEN, which results in constitutively active PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling in various cancer cell types.

  9. Our results suggest that Fatty Acid Synthase (show FASN Antibodies) upregulation and PTEN downregualtion may be involved in peritoneal dissemination for gastric cancer progression.

  10. Profilin (show PFN1 Antibodies) interacts with a protein phosphatase, phosphatase and tension homologue (PTEN), and protects it from degradation.

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN, FOXO3A (show FOXO3 Antibodies) and PKB (show AKT1 Antibodies) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. miR (show MYLIP Antibodies)-26b participates in the inflammatory response of LPS (show IRF6 Antibodies)-stimulated bAMs by modulating the NF-kappaB (show NFKB1 Antibodies) pathway through targeting PTEN.

  2. Pten expression levels in the mammary glands of dairy cows, was investigated.

  3. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (show NOS3 Antibodies) activation in vascular endothelial cells.

  4. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  5. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (show DVL2 Antibodies).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen Profile

Antigen Summary

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) antibody
  • phosphatase and tensin homolog (PTEN) antibody
  • phosphatase and tensin homolog (pten) antibody
  • 10q23del antibody
  • 2310035O07Rik antibody
  • A130070J02Rik antibody
  • AI463227 antibody
  • B430203M17Rik antibody
  • BZS antibody
  • CWS1 antibody
  • DEC antibody
  • GLM2 antibody
  • MHAM antibody
  • Mmac antibody
  • MMAC1 antibody
  • PTEN1 antibody
  • PTENP1 antibody
  • TEP1 antibody

Protein level used designations for PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

GENE ID SPECIES
19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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