Browse our anti-PTEN (PTEN) Antibodies

Full name:
anti-Phosphatase and Tensin Homolog Antibodies (PTEN)
On are 0 Phosphatase and Tensin Homolog (PTEN) Antibodies from different suppliers available. A total of 0 PTEN products are currently listed.
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
list all antibodies Gene Name GeneID UniProt
Anti-Mouse PTEN PTEN 19211 O08586
Anti-Rat PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

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More Antibodies against PTEN Interaction Partners

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. novel role for PTEN during infection and identify regulation of the PI3K pathway, a mechanism previously shown to silence autoreactive B cells, as a key physiological target to control antibody responses.

  2. This study demonstrated Pten Regulates Retinal Amacrine Cell Number by Modulating Akt (show AKT1 Antibodies), Tgfbeta (show TGFB1 Antibodies), and Erk (show EPHB2 Antibodies) Signaling in mice.

  3. Tregs ameliorated ICH (show ACE Antibodies)-induced inflammatory injury by modulating microglia/macrophage polarization toward the M2 phenotype through the IL-10 (show IL10 Antibodies)/GSK3beta (show GSK3b Antibodies)/PTEN axis

  4. Data show that macrophage M2 polarization was mediated through PTEN/PI3k/AKT (show AKT1 Antibodies) pathway activation.

  5. this study shows this study shows that infection-induced miR (show MLXIP Antibodies)-21 promotes severe, steroid-insensitive allergic airway disease by reducing PTEN expression

  6. our results showed that PTEN acts to prevent the proliferation of a progenitor niche in postnatal cerebellum predisposed to oncogenic induction of medulloblastoma

  7. miR (show MLXIP Antibodies)-20a-5p contributes to hepatic glycogen (show GYS1 Antibodies) synthesis through targeting p63 (show CKAP4 Antibodies) to regulate p53 (show TP53 Antibodies) and PTEN expression.

  8. Inhibition of PLK1 (show PLK1 Antibodies) activity or overexpression of a non-phosphorylatable PLK1 (show PLK1 Antibodies) mutant reduces the polyploid cell population.

  9. These findings demonstrate an important role for Pten in maintenance of airway epithelial phenotype integrity.

  10. Data indicate that hydrogen sulfide (show SQRDL Antibodies) H(2)S inhibits Abeta (show APP Antibodies)-induced neuronal apoptosis by attenuating mitochondrial translocation of phosphatase and tensin (show TNS1 Antibodies) homologs deleted on chromosome 10 and that activation of PI3K/AKT (show AKT1 Antibodies) signaling pathway plays a critical role in H(2)S-mediated neuronal protection. Our findings provide a novel route into the molecular mechanisms of neuronal apoptosis in Alzheimer's disease.

Human Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. ERG (show ERG Antibodies) rearrangement, but not PTEN loss, is present in a minority of potential neoplastic precursor lesions in the prostate.

  2. Data show that acquired immunodeficiency syndrome (AIDS) related diffuse large B-cell lymphoma (AR-DLBCL) frequently contain phosphorylated 70 ribosomal S6 protein-kinase (show CDK7 Antibodies) (p70S6K (show RPS6KB1 Antibodies)), a main downstream effector of the mTOR (show FRAP1 Antibodies) serine-threonine kinases (mTOR (show FRAP1 Antibodies)) pathway, and the presence of p70S6K (show RPS6KB1 Antibodies) is positively correlated with phosphorylated phosphatase and tensin homolog (pPTEN).

  3. PTEN loss was frequently found in HER2 (show ERBB2 Antibodies)-overexpressing gastroesophageal adenocarcinoma.

  4. Several germline variants in Hamartomatous Polyposis Syndrome genes were detected, among them three in ENG (show ENG Antibodies), two in BMPR1A (show BMPR1A Antibodies), one in PTEN, and one in SMAD4 (show SMAD4 Antibodies). Although some of the detected variants have been reported previously none could be definitely pathogenic or likely pathogenic.

  5. miR (show MLXIP Antibodies)-10b regulates the self-renewal of the breast CSC phenotype by inhibiting PTEN and maintaining AKT (show AKT1 Antibodies) pathway activation.

  6. The aim of this review is to shed light on the role of four different phosphatases (PTEN, PP2A (show PPP2R4 Antibodies), CDC25 (show RASGRF1 Antibodies) and DUSP1 (show DUSP1 Antibodies)) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  7. TBX2 (show TBX2 Antibodies) is a central component of the PTEN/PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathway deregulation in RMS cells and that targeting TBX2 (show TBX2 Antibodies) in RMS tumors may offer a novel therapeutic approach for RMS

  8. Taken together, recent discovery of various PTEN proteoforms, including their property to dimerize and multimerize indicates that we have a lot to learn about biological and pathophysiological functions of PTEN, which till date had remained obscure. [review]

  9. High PTEN expression is associated with osteoarthritis.

  10. this study shows that heterozygous loss of function of PTEN in human subjects has a significant effect on T- and B-cell immunity

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN, FOXO3A (show FOXO3 Antibodies) and PKB (show AKT1 Antibodies) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. the miR-17-92 cluster is involved in granulosa cell proliferation and differentiation by coordinately targeting the PTEN and BMPR2 (show BMPR2 Antibodies) genes.

  2. miR (show MYLIP Antibodies)-26b participates in the inflammatory response of LPS (show IRF6 Antibodies)-stimulated bAMs by modulating the NF-kappaB (show NFKB1 Antibodies) pathway through targeting PTEN.

  3. Pten expression levels in the mammary glands of dairy cows, was investigated.

  4. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (show NOS3 Antibodies) activation in vascular endothelial cells.

  5. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  6. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (show DVL2 Antibodies).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen Profile

Antigen Summary

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) antibody
  • phosphatase and tensin homolog (PTEN) antibody
  • phosphatase and tensin homolog (pten) antibody
  • 10q23del antibody
  • 2310035O07Rik antibody
  • A130070J02Rik antibody
  • AI463227 antibody
  • B430203M17Rik antibody
  • BZS antibody
  • CWS1 antibody
  • DEC antibody
  • GLM2 antibody
  • MHAM antibody
  • Mmac antibody
  • MMAC1 antibody
  • PTEN1 antibody
  • PTENP1 antibody
  • TEP1 antibody

Protein level used designations for PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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