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Browse our anti-PTEN (PTEN) Antibodies

Full name:
anti-Phosphatase and Tensin Homolog Antibodies (PTEN)
On are 0 Phosphatase and Tensin Homolog (PTEN) Antibodies from different suppliers available. A total of 0 PTEN products are currently listed.
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
list all antibodies Gene Name GeneID UniProt
Anti-Mouse PTEN PTEN 19211 O08586
Anti-Rat PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

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More Antibodies against PTEN Interaction Partners

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. Methylseleninic acid superactivates p53 (show TP53 Antibodies)-senescence cancer progression barrier in prostate lesions of Pten-knockout mouse

  2. Deletion or deficiency of PTEN leads to down regulation of TOP2A (show TOP2A Antibodies), dysfunction of the decatenation checkpoint and incomplete DNA decatenation in G2 and M phases.

  3. Data suggest a critical role for the I2PP2A (show SET Antibodies) protein (SET)-protein phosphatase-2A (PP2A (show PPP2R2B Antibodies)) signaling axis in Pten protein (Pten) deficient castration resistant prostate cancer (CRPC) progression.

  4. miR (show MLXIP Antibodies)-130a plays a critical role in attenuation of cardiac dysfunction and remodeling after myocardial infarction. The mechanisms involve activation of PI3K/Akt (show AKT1 Antibodies) signaling via suppression of PTEN expression.

  5. The WAP-Cre:Pten(f/f):p53 (show TP53 Antibodies)(lox.stop.lox_R270H) mice develop basal-like breast cancer that is enriched in TICs, can readily form lung metastasis, and provides a preclinical model to study both basal-like and claudin-low TNBC in immune-competent mice.

  6. RNA sequencing found progressive disruption of neural gene expression in Pten(m3m4) mice from 2-6 weeks of age, involving both immune and synaptic pathways

  7. we identified that phosphatase and tensin homolog (PTEN) was a target of miR (show MLXIP Antibodies)-141-3p. Inhibiting PTEN could alter the mitochondrial function, too. Our study suggested that mitochondria-related miR141-3p induced mitochondrial dysfunction by inhibiting PTEN

  8. early postnatal genetic deletion of PTEN that is sufficient to enable axon regeneration by adult neurons causes neuronal hypertrophy but no other detectable neuropathology

  9. timing of the loss of PTEN protein plays a critical role in determining the disease severity in myeloid malignancies as shown in a mouse model

  10. deletion of Pten in CD45 (show PTPRC Antibodies)-expressing cells induces development of mouse model T-cell acute lymphoblastic leukemia and lymphoma, but not other hematologic malignancies

Human Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN point mutation was present in 5% of clinically significant prostate tumors. PTEN loss is infrequent in clinically insignificant prostate cancer, and is associated with higher grade tumors.

  2. our results indicate that miR (show MLXIP Antibodies)-181A expression is associated with CRC (show CALR Antibodies) patients with late liver metastases through PTEN/AKT (show AKT1 Antibodies) signaling.

  3. PTEN gene polymorphisms might relate to liver cancer risk.

  4. Results demonstrate that loss of PTEN promotes resistance to immunotherapy in melanoma.

  5. Significant downregulation of LKB1 (show STK11 Antibodies) and PTEN mRNA expression levels were detected in tumour tissues compared to non-cancerous tissues.

  6. redox status of PTEN causes a functional variation in the PTEN interactome

  7. rs701848 in the PTEN gene might be a candidate pharmacogenomic factor to assess the susceptibility and prognosis in colorectal cancer patients.

  8. This study suggests a high frequency of miR (show MLXIP Antibodies)-21 overexpression and aberrant promoter methylation in down-regulation of PTEN expression in colorectal carcinoma. Loss of PTEN may be a prognostic factor for patients with CRC (show CALR Antibodies).

  9. Down-regulation of the PTEN protein is associated with breast carcinoma.

  10. These results suggest that in the progression of renal aging, high expression of TIMP-1 (show TIMP1 Antibodies) up-regulates PTEN expression indicating that PTEN and TIMP-1 (show TIMP1 Antibodies) are involved in the aging-associated impairment of renal angiogenesis

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN, FOXO3A (show FOXO3 Antibodies) and PKB (show AKT1 Antibodies) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. miR (show MYLIP Antibodies)-26b participates in the inflammatory response of LPS (show IRF6 Antibodies)-stimulated bAMs by modulating the NF-kappaB (show NFKB1 Antibodies) pathway through targeting PTEN.

  2. Pten expression levels in the mammary glands of dairy cows, was investigated.

  3. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (show NOS3 Antibodies) activation in vascular endothelial cells.

  4. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  5. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (show DVL2 Antibodies).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen Profile

Antigen Summary

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) antibody
  • phosphatase and tensin homolog (PTEN) antibody
  • phosphatase and tensin homolog (pten) antibody
  • 10q23del antibody
  • 2310035O07Rik antibody
  • A130070J02Rik antibody
  • AI463227 antibody
  • B430203M17Rik antibody
  • BZS antibody
  • CWS1 antibody
  • DEC antibody
  • GLM2 antibody
  • MHAM antibody
  • Mmac antibody
  • MMAC1 antibody
  • PTEN1 antibody
  • PTENP1 antibody
  • TEP1 antibody

Protein level used designations for PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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