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Browse our anti-PTEN (PTEN) Antibodies

Full name:
anti-Phosphatase and Tensin Homolog Antibodies (PTEN)
On www.antibodies-online.com are 0 Phosphatase and Tensin Homolog (PTEN) Antibodies from different suppliers available. A total of 0 PTEN products are currently listed.
Synonyms:
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
list all antibodies Gene Name GeneID UniProt
Anti-Mouse PTEN PTEN 19211 O08586
Anti-Rat PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

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More Antibodies against PTEN Interaction Partners

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. phenotypic and genetic changes within the pre-neoplastic mammary epithelium of mice with and without stromal PTEN expression

  2. Data suggest that expression, processing, and activation of (that is, signal transduction via) Notch1 (neurogenic locus notch homolog protein 1 (show NOTCH1 Antibodies)), Pten (phosphatase and tensin homolog), and Akt1 (thymoma viral proto-oncogene 1) are involved in oogenesis; oogenesis proceeds via both recruitment of primordial follicles and proliferation of granulosa cells.

  3. this study shows that remote ischemic postconditioning protects against renal ischemia/reperfusion injury via activation of TOPK (show PBK Antibodies)/PTEN/Akt (show AKT1 Antibodies) signaling pathway

  4. miR (show MLXIP Antibodies)-21 overexpression contributes to liver regeneration and hepatocyte proliferation by targeting PTEN

  5. Liver-specific deletion of PTEN significantly ameliorates chronic ethanol-induced increases in hepatocellular damage.

  6. Immunofluorescence studies revealed the abnormal sprouting of mossy fibers in the DG of the Pten-cKO mice prior to the onset of seizures.

  7. Data suggest that reactive oxygen species (ROS (show ROS1 Antibodies))-induced DNA damage results in hypomethylation of the PTEN promoter, upregulation of PTEN mRNA and protein, and a subsequent increase in apoptosis in irradiated lung tissue.

  8. Weight and metformin did not affect the severity of EH resulting from PTEN inactivation

  9. TNF-alpha (show TNF Antibodies) induces vascular insulin (show INS Antibodies) resistance by mechanisms that involve positive modulation of PTEN and inhibition of Akt (show AKT1 Antibodies)/eNOS (show NOS3 Antibodies)/NO signaling.

  10. In summary, our study illustrates the potential signal transduction process of PTEN while stimulated by LPS (show TLR4 Antibodies): by increasing the association of TLR4 (show TLR4 Antibodies), PTEN recruits to its phosphoinositide substrate PI(3,4,5)P3 located on the cell membrane and exerts its dephosphorylated function and subsequently depresses the activity of downstream molecule Akt (show AKT1 Antibodies) and results in activation of NF-kappaB (show NFKB1 Antibodies), followed by the secretion of inflamma...

Human Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. Transcript level expression of PTEN was analyzed by reverse transcriptase PCR and quantitative PCR in 20 GBC and 20 GSD tissue samples.

  2. The higher levels of pten mRNA expression post treatment confirmed its role in effective clearance of Leishmania.

  3. we demonstrate that PKCepsilon (show PRKCE Antibodies) cooperates with the loss of the tumor suppressor Pten for the development of prostate cancer in a mouse model. Mechanistic analysis revealed that PKCe (show PRKCE Antibodies) overexpression and Pten loss individually and synergistically upregulate the production of the chemokine (show CCL1 Antibodies) CXCL13 (show CXCL13 Antibodies), which involves the transcriptional activation of the CXCL13 (show CXCL13 Antibodies) gene

  4. PTEN inhibits the occurrence and development of endometriosis by regulating angiogenesis and the apoptosis and cell cycle of endometrial cells.

  5. findings shed new light on the NF-kappaB (show NFKB1 Antibodies)/miR (show MLXIP Antibodies)-130a/PTEN pathway in cervical cancer and add new insight regarding the carcinogenesis of cervical cancer.

  6. A significantly negative correlation between PTEN and hTERT gene expression indicates that hTERT activation and upregulation may be conferred by the loss of PTEN gene expression in hepatocellular carcinoma (HCC (show FAM126A Antibodies)).

  7. Loss of PTEN, expression and cyclin D1 (show CCND1 Antibodies) overexpression was seen in a significant number of well differentiated endometrial adenocarcinomas and complex hyperplasias with atypia, suggesting both as an early event in endometrial carcinogenesis.

  8. Hepatitis C virus (HCV) proteins could modulate PTEN by activating NF-kappaB (show NFKB1 Antibodies).

  9. These results may provide a linkage between PCa (show FLVCR1 Antibodies) chemoresistance and exosome regulatory networks and thus lead us to propose that AR, PTEN and TCF4 (show TCF4 Antibodies) genes may be the important genes which are regulated by exosome miRNAs in chemoresistance cancer cells.

  10. This review will summarize the biological roles of phosphatidylinositol 3-kinase regulatory subunit 1 and phosphatase and tensin homolog in breast cancer, with an emphasis on recent findings and the potential of phosphatidylinositol 3-kinase regulatory subunit 1 and phosphatase and tensin homolog as a therapeutic target for breast cancer therapy.

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN, FOXO3A (show FOXO3 Antibodies) and PKB (show AKT1 Antibodies) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. miR (show MYLIP Antibodies)-26b participates in the inflammatory response of LPS (show IRF6 Antibodies)-stimulated bAMs by modulating the NF-kappaB (show NFKB1 Antibodies) pathway through targeting PTEN.

  2. Pten expression levels in the mammary glands of dairy cows, was investigated.

  3. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (show NOS3 Antibodies) activation in vascular endothelial cells.

  4. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  5. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (show DVL2 Antibodies).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen Profile

Antigen Summary

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) antibody
  • phosphatase and tensin homolog (PTEN) antibody
  • phosphatase and tensin homolog (pten) antibody
  • 10q23del antibody
  • 2310035O07Rik antibody
  • A130070J02Rik antibody
  • AI463227 antibody
  • B430203M17Rik antibody
  • BZS antibody
  • CWS1 antibody
  • DEC antibody
  • GLM2 antibody
  • MHAM antibody
  • Mmac antibody
  • MMAC1 antibody
  • PTEN1 antibody
  • PTENP1 antibody
  • TEP1 antibody

Protein level used designations for PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

GENE ID SPECIES
19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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