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PHLPP2 Antibodies

(PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (AA 1295-1323), (C-Term) antibody anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (AA 1295-1323), (C-Term) antibody anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (AA 1295-1323), (C-Term) antibody (ABIN652395)

PHLPP2 Reactivity: Human FACS, IHC (p), WB Host: Rabbit Polyclonal RB15007 unconjugated

anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody (ABIN962593)

PHLPP2 Reactivity: Human, Mouse ELISA, IHC, IHC (p), IP, WB Host: Rabbit Polyclonal unconjugated

anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody (ABIN190753)

Verified PHLPP2 Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated

PHLPP2 Antibodies by Grade

Find PHLPP2 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 Antibodies by Reactivity

Find PHLPP2 Antibodies for a variety of species such as anti-Human PHLPP2, anti-Mouse PHLPP2, anti-Rat PHLPP2. The species listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 Antibodies by Application

Find PHLPP2 Antibodies validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PHLPP2 Antibodies by Host

Find PHLPP2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 Antibodies by Binding Specificity

Find PHLPP2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 Antibodies by Clonality

Find available monoclonal or polyclonal PHLPP2 Antibodies. Click on a link to go to the corresponding products.

PHLPP2 Antibodies by Clone

Find PHLPP2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 Antibodies by Conjugate

Find PHLPP2 Antibodies with a specific conjugate such as APC, Alkaline Phosphatase (AP), Biotin. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PHLPP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN392229
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN2492559
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application EIA, WB
Validations
  • (1)
Cat. No. ABIN1449986
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p)
Validations
  • (1)
Cat. No. ABIN360110
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC, WB
Validations
Cat. No. ABIN7117370
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, IF, WB
Validations
Cat. No. ABIN6991747
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
Cat. No. ABIN7269259
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
Cat. No. ABIN7093950
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC, IHC (p), WB
Validations
Cat. No. ABIN1810972
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
Cat. No. ABIN1840309
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2334566
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
Cat. No. ABIN2334575
Quantity 200 μL
Datasheet Datasheet
Reactivity Guinea Pig, Human, Mouse, Rabbit
Application IP, WB
Validations
Cat. No. ABIN1923580
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2334569
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2334570
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PHLPP2 Antibodies

Rajala, Gupta, Anderson, Rajala: "Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection." in: Mitochondrion, Vol. 13, Issue 6, pp. 566-76, (2013) (PubMed).

Sangai, Akcakanat, Chen, Tarco, Wu, Do, Miller, Arteaga, Mills, Gonzalez-Angulo, Meric-Bernstam: "Biomarkers of response to Akt inhibitor MK-2206 in breast cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 20, pp. 5816-28, (2012) (PubMed).

Gao, Furnari, Newton: "PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth." in: Molecular cell, Vol. 18, Issue 1, pp. 13-24, (2005) (PubMed).

Aliases for PHLPP2 Antibodies

PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) Antibodies
PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S) Antibodies
PH domain and leucine rich repeat protein phosphatase 2 (phlpp2) Antibodies
PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2) Antibodies
AI481772 Antibodies
C130044A18Rik Antibodies
PHLPPL Antibodies
phlppl Antibodies
Phlppl Antibodies
RGD1562857 Antibodies
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