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anti-Human NPY Antibodies:
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Alpaca (Vicugna pacos) Polyclonal NPY Primary Antibody for IEM, ICC - ABIN617905
Hogan, Terwilleger, Berman: Development of subpopulations of GABAergic neurons in cat visual cortical areas. in Neuroreport 1993
Show all 286 Pubmed References
Human Polyclonal NPY Primary Antibody for IHC, IHC (fro) - ABIN4338812
Gujar, Ibrahim, Tamrakar, Cherian, Briski: Hindbrain lactostasis regulates hypothalamic AMPK activity and metabolic neurotransmitter mRNA and protein responses to hypoglycemia. in American journal of physiology. Regulatory, integrative and comparative physiology 2014
Show all 6 Pubmed References
Human Polyclonal NPY Primary Antibody for IHC (p), WB - ABIN3043892
Wang, Chen, Yue, Bai, Kou, Jin: Xiaoyaosan decoction regulates changes in neuropeptide y and leptin receptor in the rat arcuate nucleus after chronic immobilization stress. in Evidence-based complementary and alternative medicine : eCAM 2012
Show all 4 Pubmed References
Human Monoclonal NPY Primary Antibody for ELISA, WB - ABIN562025
Bojkowska, Hamczyk, Tsai, Riggan, Rissman: Neuropeptide Y influences acute food intake and energy status affects NPY immunoreactivity in the female musk shrew (Suncus murinus). in Hormones and behavior 2008
Show all 2 Pubmed References
Human Polyclonal NPY Primary Antibody for IF (p), IHC (p) - ABIN724475
Duan, Hao, Fan, Wang, Liu, Hao, Xu, Liu, Zhang: The role of neuropeptide Y and aquaporin 4 in the pathogenesis of intestinal dysfunction caused by traumatic brain injury. in The Journal of surgical research 2013
Show all 2 Pubmed References
Human Polyclonal NPY Primary Antibody for ICC, IF - ABIN4338814
Jimenez-Mateos, Arribas-Blazquez, Sanz-Rodriguez, Concannon, Olivos-Ore, Reschke, Mooney, Mooney, Lugara, Morgan, Langa, Jimenez-Pacheco, Silva, Mesuret, Boison, Miras-Portugal, Letavic, Artalejo et al.: microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus. ... in Scientific reports 2015
Human Monoclonal NPY Primary Antibody for ELISA, WB - ABIN395848
Ide, Hara, Ohno, Tamano, Koseki, Naka, Maruyama, Kaneda, Yoshioka, Minami: Opposing roles of corticotropin-releasing factor and neuropeptide Y within the dorsolateral bed nucleus of the stria terminalis in the negative affective component of pain in rats. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Human Monoclonal NPY Primary Antibody for ELISA, WB - ABIN518402
Yang, Fung, Rothwell, Tianmei, Weickert: Increased interstitial white matter neuron density in the dorsolateral prefrontal cortex of people with schizophrenia. in Biological psychiatry 2010
Human Polyclonal NPY Primary Antibody for ICC, IHC (fro) - ABIN153136
Reeber, Loeschel, Franklin, Sillitoe: Establishment of topographic circuit zones in the cerebellum of scrambler mutant mice. in Frontiers in neural circuits 2013
Neuropeptide Y mRNA content decreased 6 h after a meal, but increased to prefeeding levels by 24 h.
Both structural (+1128T/C) and promoter polymorphisms (-399 T/C) of Neuropeptide Y are strongly associated with type-II diabetes susceptibility in Gujarat population which at least in part, may result in higher levels of Neuropeptide Y thereby suggesting its crucial role in type-II diabetes susceptibility.
Hypermethylation of WIF1 (WNT inhibitory factor 1 (show WIF1 Antibodies)) and NPY (neuropeptide Y) genes was significantly higher in tumor tissue compared to normal tissue, independently of tumor stage.
Our results provided clinical evidences for NPY participating in the bone healing process in a nonhypothalamic manner, most probably by directly promoting osteogenesis of mesenchymal stem cells.
In conclusion, the obtained results demonstrate the probable role of NPY SNPs in susceptibility to multiple sclerosis within the Iranian population.
Neuropeptide Y is the best dipeptidyl peptidase 4 (DPP4 (show DPP4 Antibodies))-substrate in blood, being truncated by soluble and membrane DPP4 (show DPP4 Antibodies), respectively. The decline of soluble DPP4 (show DPP4 Antibodies) in acute depression could be reversed upon anti-depressive treatment.
study implicates NPY as a potential target in antihypertensive therapies for preeclampsia patients
NPY is efficiently cleaved by FAP indicating a potential function for FAP in neuropeptide regulation within liver and cancer biology.
NPY plays important roles in the pathogenesis and pathophysiology of pituitary adenomas, as shown in this clinical study.
NPY levels were higher in both obese and non-obese PCOS patients compared to healthy controls.
Authors observed that NPY levels were decreased in two (show ATXN3 Antibodies)Machado-Joseph disease patients' cerebella.
Findings suggest that neuropeptide Y is expressed by distinct populations of neurons can modulate afferent and efferent projections of the central amygdala via presynaptic Y2 receptors located at inhibitory and excitatory synapses.
arcuate nucleus NPY neuropathway to the paraventricular nucleus and dorsomedial hypothalamus is pivotal in obesity-induced elevations in sympathetic nerve activity.
NPY promotes airway hyperresponsiveness through the induction of Rho kinase activity and phosphorylation of myosin light chain, which induces airway smooth muscle contraction.
stress alters CA1 (show CA1 Antibodies) circuit function through the impairment of endogenous NPY release, potentially contributing to heightened anxiety
Npy expression is decreased in the cingulate cortex following chronic unpredictable stress.
The results showed that NPY system activity is increased in a time- and space-dependent manner during bone repair.
Decreased neuropeptide Y (NPY) expression in the extended amygdala might be causally linked with the depression induced following type 2 diabetes and that the antidepressant action of imipramine in diabetic mice might be mediated by NPY-NPY Y1 receptor system.
lipolytic/thermogenic signaling, beta3-adrenergic receptor (show ADRB3 Antibodies)/hormone sensitive lipase (show LIPE Antibodies), was markedly activated in white adipose tissue of NPY(-/-) mice compared with that of NPY(+/+) mice.
These data establish the existence of a microRNA-mediated cross talk between enteric neurons producing NPY and intestinal epithelial cells, and the potential of neuropeptide-regulated miRNAs as potential therapeutic molecules for the management of inflammation-associated tumors in the gut (show GUSB Antibodies).
Stress may be associated with elevated peripheral neuropeptide Y level, which was observed to be associated with exacerbated airway inflammation in asthmatic mice.
Results show that the PP-fold is not important for recognition of peptide YY or neuropeptide Y at Y receptors.
NPY has a positive inotropic effect in isolated rat cardiac myocytes, which involves increase in Ca2 (show CA2 Antibodies)+ release after activation of Y1 NPY receptor
High dietary copper appears to increase feed intake and promote weight gain by enhancing NPY concentration and NPY mRNA expression level in the hypothalamus of pigs.
Neuropeptide Y was released from the lung tissue of brain-dead pigs, and its concentration was related to the extent of neurogenic pulmonary edema
Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin (show LEP Antibodies)-NPY and insulin (show INS Antibodies) signaling pathways.
Data indicate that increased body weight gain during juvenile development accelerates sexual maturation in heifers, coincident with reciprocal changes in circulating concentrations of leptin (show LEP Antibodies) and hypothalamic neuropeptide Y (NPY) release.
There is a strong association between putative favorable allelic variants (SNP) of neuropeptide Y, leptin (show LEP Antibodies), and IGF-1 (show IGF1 Antibodies) genes, and residual feed intake, when animals were grazing on a high-quality, high-availability pasture.
The NPY SNP (NPY1) was associated with the prevalence of the animal being in calf 100 d after calving and 305-d milk yield in the first lactation.
NPY tended to increase serum growth hormone (show GH1 Antibodies), which appeared to be a consequence of increased pulse amplitude. Infusion of NPY also increased CSF (show CSF2 Antibodies) growth hormone-releasing hormone (show GHRH Antibodies).
Data show that PKA and PKC (show PKC Antibodies) pathways are involved in the differential regulation of production of the neuropeptides (Met)enkephalin, galanin (show GAL Antibodies), somatostatin (show SST Antibodies), NPY, and VIP (show Vip Antibodies).
The present investigation provides results of increased vasocontractile effect of NOR and decreased enhancing effect of NPY on NOR vasoconstriction in the rabbit facial artery after carotid occlusion that is related to altered endothelium function
NPY acts as an orexigenic factor in the zebrafish.
Neuropeptide Y/peptide YY receptor Y2 duplicate in zebrafish with unique introns displays distinct peptide binding properties.(
Developmental expression of zYb and zYc receptors suggests a role for neuropeptide Y (NPY) in organogenesis.
In this study described the the lateral line presence of NPY-like immunoreactivity (IR) in of the Antarctic nototheniod fish. Differences in size and cellular composition between the two neuromasts were presen NPY immunoreactivity.
A 2-day fast increased NPY gene expression in the supraoptic nucleus and paraventricular nucleus.
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
, neuropeptide Ya
, prepro-neuropeptide Y
, pro-neuropeptide Y
, pro-neuropeptide Y preproprotein
, neuropeptide Yb
, pre-pro hormone
, preproneuropeptide Y, preproNPY