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Browse our Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Proteins (CHST14)

Full name:
Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Proteins (CHST14)
On www.antibodies-online.com are 5 Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) Proteins from 2 different suppliers available. Additionally we are shipping Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Antibodies (31) and many more products for this protein. A total of 38 Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 products are currently listed.
Synonyms:
2600016L03Rik, ATCS, D4ST-1, d4st1, HNK1ST, MGC136487, wu:fc04a01, zgc:136487
list all proteins Gene Name GeneID UniProt
CHST14 113189 Q8NCH0
CHST14 72136 Q80V53
Rat CHST14 CHST14 691394  

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Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Proteins (CHST14) by Origin

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More Proteins for Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Interaction Partners

Human Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) interaction partners

  1. patients with CHST14/D4ST1 deficiency develop progressive multisystem fragility-related manifestations, establishment of a comprehensive and detailed natural history and health-care guidelines as well as further elucidation of the pathophysiology in view of future etiology-based therapy are crucial

  2. CHST14 gene mutations are associated with musculocontractural type of Ehlers-Danlos syndrome.

  3. We report on the detailed clinical characterization of two sisters with musculocontractural Ehlers-Danlos syndrome caused by a homozygous mutation in the CHST14 gene.

  4. Loss of dermatan-4-sulfotransferase 1 (D4ST1/CHST14) function represents the first dermatan sulfate biosynthesis defect, "dermatan sulfate-deficient adducted thumb-clubfoot syndrome".

  5. Musculocontractural Ehlers-Danlos Syndrome (former EDS type VIB (show SEMA6B Proteins)) and adducted thumb clubfoot syndrome (ATCS) represent a single clinical entity caused by mutations in the dermatan-4-sulfotransferase 1 encoding CHST14 gene.

  6. A homozygous CHST14 (carbohydrate sulfotransferase 14) mutation in the two familial cases and compound heterozygous mutations in four sporadic cases of Ehlers-Danlos syndrome, were identified.

  7. D4ST-1 is a key enzyme and is indispensable in the formation of important functional domains in dermatan sulfate and cannot be compensated by other 4-O-sulfotransferases

  8. dermatan-4-sulfotransferase 1 has a role in adducted thumb-clubfoot syndrome

  9. human D4ST-1, C4ST-1 (show CHST11 Proteins), and S4ST-2 have differential roles in dermatan sulfate biosynthesis

  10. D4ST-1 is encoded by a single exon located on human chromosome 15q14; type II membrane protein of 376 amino acids with a 43-amino acid cytoplasmic domain and a 316-amino acid luminal domain containing two potential N-linked glycosylation sites

Mouse (Murine) Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) interaction partners

  1. Deficiency for Chst14 results in decreased neurogenesis and diminished proliferation of neural stem cells.

  2. analysis of the three CS sulfotransferases in the developing neocortex: uronyl 2-O-sulfotransferase (UST), N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (4,6-ST) and dermatan 4-O-sulfotransferase-1 (D4-ST)

Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) Protein Profile

Protein Summary

This gene encodes a member of the HNK-1 family of sulfotransferases. The encoded protein transfers sulfate to the C-4 hydroxyl of N-acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb-clubfoot syndrome.

Alternative names and synonyms associated with Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14)

  • carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (CHST14)
  • carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (Chst14)
  • carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (chst14)
  • 2600016L03Rik protein
  • ATCS protein
  • D4ST-1 protein
  • d4st1 protein
  • HNK1ST protein
  • MGC136487 protein
  • wu:fc04a01 protein
  • zgc:136487 protein

Protein level used designations for CHST14

carbohydrate sulfotransferase 14 , dermatan 4 sulfotransferase 1 , dermatan 4-sulfotransferase 1 , dermatan-4-sulfotransferase-1 , D4ST-1 , zD4ST-1

GENE ID SPECIES
113189 Homo sapiens
511245 Bos taurus
72136 Mus musculus
691394 Rattus norvegicus
404732 Danio rerio
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