Browse our Glucuronic Acid Epimerase Proteins (GLCE)

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Glucuronic Acid Epimerase Proteins (GLCE)
On are 10 Glucuronic Acid Epimerase (GLCE) Proteins from 3 different suppliers available. Additionally we are shipping Glucuronic Acid Epimerase Antibodies (17) and Glucuronic Acid Epimerase Kits (6) and many more products for this protein. A total of 38 Glucuronic Acid Epimerase products are currently listed.
1110017N23Rik, AI747411, C130034A12Rik, Hsepi, MGC79110, RGD1565253
list all proteins Gene Name GeneID UniProt
Rat GLCE GLCE 363073  
GLCE 26035 O94923
GLCE 93683 Q9EPS3

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Glucuronic Acid Epimerase Proteins (GLCE) by Origin

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More Proteins for Glucuronic Acid Epimerase Interaction Partners

Human Glucuronic Acid Epimerase (GLCE) interaction partners

  1. The GLCE gene polymorphism rs3865014 appears to have biological relevance in human pathophysiology.

  2. C5-epimerase and 2-O-sulfotransferase (show HS2ST1 Proteins) in association generate extended domains of consecutive GlcNS-IdoA2S Sequence.

  3. GLCE may be used as a potential model to study the functional role of intratumor cell heterogeneity in prostate cancer progression.

  4. activation of angiogenesis as a main molecular mechanism of pro-oncogenic effect of GLCE in prostate cancer.

  5. positive correlation between miRNA-218 and GLCE mRNA, and negative correlation between miRNA-218 and GLCE protein levels in breast tissues and primary tumors in vivo, supporting a direct involvement of miRNA-218 in posttranscriptional regulation of GLCE

  6. A correlation was observed between D-glucuronyl C5-epimerase (GLCE), TCF4 (show TCF4 Proteins) and beta-catenin (show CTNNB1 Proteins) expression in breast cancer cells and primary tumors, suggesting an important role for TCF4 (show TCF4 Proteins)/beta-catenin (show CTNNB1 Proteins) in regulating GLCE expression both in vitro and in vivo.

  7. The biphasic mode of C(5)-epi (show TFPI Proteins) offers a novel mechanism to regulate the biosynthesis of HS with the desired biological functions.

  8. SNPs in GLCE are associated with triglyceride and HDL (show HSD11B1 Proteins)-C levels in Turks, and mouse studies support a role for glce in lipid metabolism.

  9. The regulation of GLCE expression by 2 cis (show CISH Proteins)-acting elements of the beta-catenin (show CTNNB1 Proteins)-TCF4 (show TCF4 Proteins) complex located in the enhancer region of the promoter are reported.

  10. in 82-84% of human breast tumors there is either downregulation or loss of D-glucuronyl C5-epimerase mRNA expression and significant decrease of the protein content

Mouse (Murine) Glucuronic Acid Epimerase (GLCE) interaction partners

  1. Results found that loss of Glce leads to a delayed onset of hypertrophic differentiation combined with an expanded region of proliferating chondrocytes indicating increased Ihh (show IHH Proteins) signaling.

  2. analysis of the activity of heparan sulfate C5-epimerase and its mutants by using engineered 2-O-sulfotransferase (show HS2ST1 Proteins)

  3. modification of heparan sulfate by glucuronyl C5-epimerase is required for controlling the activity of molecules that are instructive for early lymphoid tissue morphogenesis

  4. NDST-1 (show NDST1 Proteins) and C5-epimerase have roles in heparan sulfate structure alterations in mouse tissue

Glucuronic Acid Epimerase (GLCE) Protein Profile

Protein Summary

Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005

Alternative names and synonyms associated with Glucuronic Acid Epimerase (GLCE)

  • glucuronic acid epimerase (Glce)
  • glucuronic acid epimerase (GLCE)
  • glucuronic acid epimerase (glce)
  • glucuronyl C5-epimerase (Glce)
  • 1110017N23Rik protein
  • AI747411 protein
  • C130034A12Rik protein
  • Hsepi protein
  • MGC79110 protein
  • RGD1565253 protein

Protein level used designations for GLCE

D-glucuronyl C5-epimerase , glucuronyl C5-epimerase , glucuronic acid epimerase , D-glucuronyl C5-epimerase-like , d-glucuronyl C5-epimerase-like , UDP-glucuronic acid epimerase , heparan sulfate C5-epimerase , heparan sulfate epimerase , heparin/heparan sulfate-glucuronic acid C5-epimerase , heparin/heparan sulfate:glucuronic acid C5-epimerase , heparosan-N-sulfate-glucuronate 5-epimerase , hsepi , heparan sulfate-glucuronic acid C5-epimerase , heparin sulfate C5-epimerase

363073 Rattus norvegicus
415566 Gallus gallus
432242 Xenopus laevis
453542 Pan troglodytes
487622 Canis lupus familiaris
694999 Macaca mulatta
100019166 Monodelphis domestica
100052581 Equus caballus
100154444 Sus scrofa
100402503 Callithrix jacchus
100457760 Pongo abelii
100556549 Anolis carolinensis
100592444 Nomascus leucogenys
26035 Homo sapiens
281195 Bos taurus
93683 Mus musculus
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