Browse our HS6ST2 Proteins (HS6ST2)

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Heparan Sulfate 6-O-Sulfotransferase 2 Proteins (HS6ST2)
On are 4 Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) Proteins from 1 different suppliers available. Additionally we are shipping HS6ST2 Kits (16) and HS6ST2 Antibodies (10) and many more products for this protein. A total of 32 HS6ST2 products are currently listed.
6OST2, fb80f12, hs6st, HS6ST-2, RGD1563872, RGD1564397, wu:fb80f12
list all proteins Gene Name GeneID UniProt
HS6ST2 50786 Q80UW0
Rat HS6ST2 HS6ST2 302489  
HS6ST2 90161 Q96MM7

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HS6ST2 Proteins (HS6ST2) by Origin

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More Proteins for HS6ST2 Interaction Partners

Mouse (Murine) Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) interaction partners

  1. Overexpression or silencing of HS6ST2 significantly enhanced or abrogated the effects of fibroblast growth factor (FGF)2 (show FGF2 Proteins) on chondrocyte growth, respectively.

  2. Hs6st2 knockout mice had increased body weight, insulin (show INS Proteins) resistance and high thyroid hormone (show PTH Proteins) level.

  3. both HS6ST-1 (show HS6ST1 Proteins) and HS6ST-2 are involved in 6-O-sulfation of heparin and that the proper packaging and storage of tryptase (show TPSAB1 Proteins)

  4. Results indicate that HS6ST2 gene influences expression of genes linked to aggrecan (show ACAN Proteins) metabolism and is implicated in pathogenesis of osteoarthritis.

  5. 6OST2 is more mesenchymal than its isoenzymes during development

  6. Data show that high expression of 6-O-sulfotransferase (6-OST)-1, 2, or 3 resulted in increased 6-O-sulfation of N-sulfated (show SULF1 Proteins) and N-acetylated glucosamine units, and in altered heparan sulfate domain structure.

Human Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) interaction partners

  1. HS6ST-1 (show HS6ST1 Proteins) and HS6ST-2 have roles in regulating the angiogenic program in ovarian cancer cells affecting HB-EGF (show HBEGF Proteins) signaling and subsequent expression of angiogenic cytokines by cancer cells

  2. HS6ST2 knockdown disrupts epithelial-mesenchymal transition and suggesets that HS6ST2 potentiates Notch (show NOTCH1 Proteins) signaling in pancreatic cancer cells.

  3. we have characterized HS6ST-2 and HS6ST-1 (show HS6ST1 Proteins) human isologues, including their chromosomal localizations,HS6STs could also transfer sulfate to N -sulfoglucosamine residues located at the non-reducing terminal of HS with high affinity.

Zebrafish Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) interaction partners

  1. hs6st2 is required for the branching morphogenesis of the caudal vein during embryonic development.

HS6ST2 Protein Profile

Protein Summary

Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with HS6ST2

  • heparan sulfate 6-O-sulfotransferase 2 (HS6ST2)
  • heparan sulfate 6-O-sulfotransferase 2 (Hs6st2)
  • heparan sulfate 6-O-sulfotransferase 2 (hs6st2)
  • 6OST2 protein
  • fb80f12 protein
  • hs6st protein
  • HS6ST-2 protein
  • RGD1563872 protein
  • RGD1564397 protein
  • wu:fb80f12 protein

Protein level used designations for HS6ST2

heparan sulfate 6-O-sulfotransferase 2 , heparan-sulfate 6-O-sulfotransferase 2 , heparan-sulfate 6-O-sulfotransferase 2-like , HS6ST-2 , mHS6ST-2 , cHS6ST-2 , heparan sulfate 6-O-sulfotransferase-2 , HS 6-OST-2

473786 Pan troglodytes
492142 Canis lupus familiaris
517768 Bos taurus
100054266 Equus caballus
100351196 Oryctolagus cuniculus
100398118 Callithrix jacchus
100439955 Pongo abelii
50786 Mus musculus
302489 Rattus norvegicus
90161 Homo sapiens
395150 Gallus gallus
378450 Danio rerio
101110034 Ovis aries
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