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Browse our HHIP Proteins (HHIP)

Full name:
Hedgehog Interacting Protein Proteins (HHIP)
On are 3 Hedgehog Interacting Protein (HHIP) Proteins from 2 different suppliers available. Additionally we are shipping HHIP Antibodies (61) and HHIP Kits (39) and many more products for this protein. A total of 107 HHIP products are currently listed.
fd99f01, Hhip1, HIP, RGD1564108, wu:fc52e12, wu:fd99f01, Xhip, zgc:153478
list all proteins Gene Name GeneID UniProt
HHIP 64399 Q96QV1
HHIP 15245 Q7TN16
Rat HHIP HHIP 291936  

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HHIP Proteins (HHIP) by Origin

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More Proteins for HHIP Interaction Partners

Zebrafish Hedgehog Interacting Protein (HHIP) interaction partners

  1. Hhip regulates muscle development both by sequestering Hedgehog and by modulating localization of Smoothened

Xenopus laevis Hedgehog Interacting Protein (HHIP) interaction partners

  1. Localized expression of Xhip may counteract certain overlapping signaling activities, which inhibit the induction of olfactory and lens placodes.

Human Hedgehog Interacting Protein (HHIP) interaction partners

  1. HHIP - candidate gene for Chronic Obstructive Pulmonary Disease identified by Genome-wide association studies.

  2. Shh (show SHH Proteins)-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh (show SHH Proteins) signaling.

  3. HHIP might be a diagnostic or prognostic marker in glioma and help to the detection of these tumors in early stages of disease.

  4. HHIP is located within genes previously associated with chronic obstructive pulmonary disease susceptibility.

  5. Genetic variants in HHIP are associated with FEV1 in subjects with chronic obstructive pulmonary disease.

  6. The data demonstrated that loss of expression of HHIP and PTCH (show PTCH1 Proteins) is associated with the methylation of gene promoters

  7. We show that GPC3 (show GPC3 Proteins), an hepatocellular carcinoma biomarker and Hh mediator, regulates human stellate cell viability by regulating Hh signaling.

  8. Data indicate that the Shh (show SHH Proteins) signaling transduction is facilitated by binding of Shh (show SHH Proteins) to its receptor protein, Ptch (show PTCH1 Proteins), and show the complex structure of Shh (show SHH Proteins)-Hhip.

  9. our study suggests that the HHIP gene may be involved in COPD susceptibility in Chinese Han population.

  10. HHIP, HDAC4 (show HDAC4 Proteins), NCR3 (show NCR3 Proteins) and RARB (show RARB Proteins) polymorphisms may have a role in impaired lung function that begins in early life

Cow (Bovine) Hedgehog Interacting Protein (HHIP) interaction partners

  1. The HHIP gene that is known to be associated with stature in humans was strongly associated with direct calving difficulty in the present study.

Mouse (Murine) Hedgehog Interacting Protein (HHIP) interaction partners

  1. PTCH1 (show PTCH1 Proteins), PTCH2 (show PTCH2 Proteins) and HHIP1 all contribute to ligand-dependent antagonism of sonic hedgehog (show SHH Proteins) signaling.

  2. Estradiol improves the recovery of injured nerves by downregulating the Shh (show SHH Proteins) inhibitor hedgehog-interacting protein and increasing Shh (show SHH Proteins)-induced angiogenesis.

  3. hedgehog (show SHH Proteins) antagonists patched 1 (show PTCH1 Proteins) and Hhip1 have roels in growth and pattern of the mammalian neural tube

  4. hypothesis for a functional link between nitric oxide and Shh (show SHH Proteins) signaling and for a nonredundant role of Hip and Ptc1 (show PTCH1 Proteins) in the adult brain

  5. These data indicate that Hh signaling plays a role in adult gut (show GUSB Proteins) epithelial homeostasis by regulating epithelial cell migration from crypt to villus tip and by enhancing apoptosis.

  6. These results strongly suggest that GSK3beta phosphorylates Sufu (show SUFUH Proteins) to positively regulate Hedgehog (show SHH Proteins) signaling in mammalian cells.

HHIP Protein Profile

Protein Summary

This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.

Alternative names and synonyms associated with HHIP

  • hedgehog interacting protein (hhip)
  • hedgehog interacting protein (HHIP)
  • hedgehog interacting protein (LOC100226393)
  • hedgehog interacting protein (Hhip)
  • Hedgehog-interacting protein (Hhip)
  • hedgehog-interacting protein-like (LOC100855424)
  • fd99f01 protein
  • Hhip1 protein
  • HIP protein
  • RGD1564108 protein
  • wu:fc52e12 protein
  • wu:fd99f01 protein
  • Xhip protein
  • zgc:153478 protein

Protein level used designations for HHIP

Hip , hedgehog-interacting protein , uki , ukkie , hedgehog interacting protein , hedgehog-interacting protein-like , Hedgehog-interacting protein-like

326102 Danio rerio
380097 Xenopus laevis
448466 Xenopus (Silurana) tropicalis
461521 Pan troglodytes
701205 Macaca mulatta
100226393 Taeniopygia guttata
100404963 Callithrix jacchus
100434376 Pongo abelii
100476875 Ailuropoda melanoleuca
64399 Homo sapiens
100344588 Oryctolagus cuniculus
100728644 Cavia porcellus
100525059 Sus scrofa
540830 Bos taurus
422460 Gallus gallus
101111396 Ovis aries
15245 Mus musculus
291936 Rattus norvegicus
100855424 Canis lupus familiaris
475452 Canis lupus familiaris
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