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Low Density Lipoprotein Receptor Proteins

(Low Density Lipoprotein Receptor (LDLR))
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].

32 results

LDLR Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275138
 
LDLR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275139
 
LDLR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Catalog No. ABIN1309277
 
LDLR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275140
 
LDLR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Catalog No. ABIN2181455
 
LDLR Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN5526601
 
LDLR Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Catalog No. ABIN7123785
 
LDLR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Catalog No. ABIN7320327
 
LDLR Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491325
 
LDLR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN1780661
 
LDLR Origin: Rabbit Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Catalog No. ABIN7013410
 
LDLR Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Catalog No. ABIN2870752
 
LDLR Origin: Human Host: HEK-293 Cells Recombinant >80 % as determined by SDS-PAGE. Active
Catalog No. ABIN5954921
 
LDLR Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505399
 
LDLR Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505737
 
LDLR Origin: Human Host: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7317949
 
LDLR Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Catalog No. ABIN7577920
 
LDLR Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Catalog No. ABIN7577919
 
LDLR Origin: Human Host: Mammalian Cells Recombinant WB, SDS, ELISA
Catalog No. ABIN7577918
 
LDLR Origin: Human Host: Mammalian Cells Recombinant WB, SDS, ELISA
Catalog No. ABIN7577917
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Cynomolgus
    • Rat
    • Rabbit
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • Wheat germ
    • Human Cells
    • Yeast
  • Binding Specificity
    • AA 22-788
    • partial
    • AA 263-509
    • AA 1-790
    • AA 1-860
    • AA 105-205
    • AA 22-790
    • AA 22-807
    • AA 25-186
    • AA 335-588
    • AA 455-607
    • AA 497-742
    • AA 9-765
  • Conjugate
    • His tag
    • Fc Tag
    • GST tag
    • His tag,AVI tag
    • His tag,AVI tag,Biotin
    • His tag,GST tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
    • Un-conjugated
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
  • Biological Activity
    • Biologically Active
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • CUSABIO
    • OriGene

Latest Publications for our Low Density Lipoprotein Receptor Proteins

Basak, Verghese, Yoon, Kim, Holtzman: "Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of A? uptake and degradation by astrocytes." in: The Journal of biological chemistry, Vol. 287, Issue 17, pp. 13959-71, (2012) (PubMed).

Prunotto, Carnevali, Candiano, Murtas, Bruschi, Corradini, Trivelli, Magnasco, Petretto, Santucci, Mattei, Gatti, Scolari, Kador, Allegri, Ghiggeri: "Autoimmunity in membranous nephropathy targets aldose reductase and SOD2." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 507-19, (2010) (PubMed).

Aliases for Low Density Lipoprotein Receptor Proteins

low density lipoprotein receptor (LDLR) Proteins
low density lipoprotein receptor (Ldlr) Proteins
low density lipoprotein receptor a (ldlra) Proteins
low density lipoprotein receptor S homeolog (ldlr.S) Proteins
low density lipoprotein receptor L homeolog (ldlr.L) Proteins
FH Proteins
FHC Proteins
fhc Proteins
Hlb301 Proteins
LDLA Proteins
LDLCQ2 Proteins
ldlcq2 Proteins
ldlr Proteins
ldlr-a Proteins
ldlr-b Proteins
ldlr2-a Proteins
LDLRA Proteins
LDL receptor-2 Proteins
LDL receptor 1 Proteins
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