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Browse our Arrestin 3 Proteins (ARRB2)

Full name:
Arrestin, beta 2 Proteins (ARRB2)
On are 8 Arrestin, beta 2 (ARRB2) Proteins from 5 different suppliers available. Additionally we are shipping Arrestin 3 Antibodies (87) and Arrestin 3 Kits (30) and many more products for this protein. A total of 128 Arrestin 3 products are currently listed.
AI326910, ARB2, ARR2, arrb2, arrestin, AW122872, BARR2, BARRES, betaarr2, zgc:64007
list all proteins Gene Name GeneID UniProt
ARRB2 409 P32121
ARRB2 25388 P29067
ARRB2 216869 Q91YI4

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Arrestin 3 Proteins (ARRB2) by Origin

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Top referenced Arrestin 3 Proteins

  1. Human Arrestin 3 Protein expressed in Wheat germ - ABIN1345726 : Quack, Woznowski, Potthoff, Palmer, Königshausen, Sivritas, Schiffer, Stegbauer, Vonend, Rump, Sellin: PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia. in The Journal of biological chemistry 2011 (PubMed)

More Proteins for Arrestin 3 Interaction Partners

Human Arrestin, beta 2 (ARRB2) interaction partners

  1. The downregulation of beta-arrestins 1/2 in saphenous vein endothelial cells (SVECs) prevented the shear stress-induced rise in levels of phosphorylation of Akt (show AKT1 Proteins) and endothelial nitric oxide synthase (eNOS (show NOS3 Proteins), Serine 1177).

  2. CRIP1a (show CRIP1 Proteins) can compete with beta-arrestins for interaction with C-terminal CB1R (show CNR1 Proteins) domains that could affect agonist-driven, beta-arrestin-mediated internalization of the CB1R (show CNR1 Proteins).

  3. RACK1 (show GNB2L1 Proteins) and beta-arrestin2 inhibit the dimerization of PDE4D5.

  4. Suggest that fenoterol inhibited AICAR-induced AMPK alpha1 activation and TNF-alpha release through beta-arrestin-2 in THP-1 cells.

  5. Substance P (show TAC1 Proteins) enhances tissue factor (show F3 Proteins) release from granulocyte-macrophage colony-stimulating factor (show CSF2 Proteins)-dependent macrophages via the p22phox (show CYBA Proteins)/beta-arrestin 2/Rho A (show RHOA Proteins) signaling pathway.

  6. beta-arrestins regulate oxidative stress in a Nox4 (show NOX4 Proteins)-dependent manner and increase fibrosis in heart failure.

  7. Results demonstrate that betaArr2 signaling may be an important pathway for TAAR1 function and that the activation of the TAAR1-D2R complex negatively modulates GSK3b signaling

  8. Role for engagement of BARR2 by the transactivated EGFR in agonist-specific regulation of delta receptor activation of ERK1/2

  9. Data suggest that thrombin (show F2 Proteins) can directly activate PAR2 (show F2RL1 Proteins) vasorelaxation, signal transduction (stimulating both calcium and MAP kinase (show MAPK1 Proteins) responses), and triggering beta-arrestin recruitment (both beta-arrestin 1 (show ARRB1 Proteins) and 2).

  10. a beta-arrestin signalling cycle that is catalytically activated by the GPCR and energetically coupled to the endocytic machinery

Cow (Bovine) Arrestin, beta 2 (ARRB2) interaction partners

  1. The fraction of arrestin2 molecules found in clusters larger than 100nm correlates with the magnitude of ligand-induced CCR5 internalization.

  2. K2A mutations in arrestin-1 (show SAG Proteins), -2, and -3 significantly reduced their binding to active phosphorhodopsin.

  3. Results reveal that multiple intramolecular interactions coordinately regulate arrestin2 interaction with clathrin, highlighting this interaction as a critical step in regulating receptor trafficking.

Mouse (Murine) Arrestin, beta 2 (ARRB2) interaction partners

  1. Beta-arrestin-2 with beta-arrestin-1 shared common mechanisms to suppress podocyte autophagy by negative regulation of ATG12-ATG5 conjugation.

  2. [beta]-arrestin2 regulates intestinal mucosal inflammation under both homeostatic and colitic conditions. Its mode of action involves negative regulation of T-cell activation and its requirement for induction of regulatory T cells.

  3. Results suggest that the antipruritic effects of kappa opioid receptor (show OPRK1 Proteins) agonists may not require betaarrestin2

  4. that pro- and anti-inflammatory activities of beta-arrestin2 are determined by beta-arrestin2 ubiquitination and that changes in USP20 (show USP20 Proteins) expression and/or activity can therefore regulate inflammatory responses

  5. This shows that mood stabilizers lamotrigine, lithium and valproate can exert behavioral effects in mice by disrupting the beta-arrestin 2-mediated regulation of Akt/GSK3 signaling by D2 dopamine receptors.

  6. findings show for the first time that Ang II (show AGT Proteins) receptor signaling to beta-arrestin regulates ARF6 (show ARF6 Proteins) activation. These proteins together control receptor endocytosis and ultimately cell migration.

  7. These results reveal that the protective effect of deficiency of Arrb2 is due to loss of negative regulation of Akt (show AKT1 Proteins).

  8. that Insulin-like growth factor-1 (show IGF1 Proteins) contributes to the mucosal repair by beta-arrestin2-mediated extracellular signal-regulated kinase signaling in experimental colitis

  9. ARRB2 is not involved in hepatocellular carcinogenesis.

  10. morphine activated JNK2 through an arrestin-independent Src- and PKC-dependent mechanism, whereas fentanyl activated JNK2 through a Src-GRK3/arrestin-2-dependent and PKC-independent mechanism.

Xenopus laevis Arrestin, beta 2 (ARRB2) interaction partners

  1. Arrb2 physically interacts with the beta subunit (show POLG Proteins) of trimeric G-proteins and Dishevelled (show DVL2 Proteins), the interaction between arrb2 and Dishevelled (show DVL2 Proteins) is promoted by the beta/gamma subunits of trimeric G-proteins.

Zebrafish Arrestin, beta 2 (ARRB2) interaction partners

  1. results suggest that a functional interaction between beta-arrestin 2 and Smoothened may be critical to regulate hedgehog (show SHH Proteins) signaling in zebrafish development

Arrestin 3 (ARRB2) Protein Profile

Protein Summary

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Arrestin 3 (ARRB2)

  • arrestin, beta 2 (ARRB2)
  • arrestin, beta 2 (arrb2)
  • arrestin, beta 2 (Arrb2)
  • arrestin, beta 2b (arrb2b)
  • AI326910 protein
  • ARB2 protein
  • ARR2 protein
  • arrb2 protein
  • arrestin protein
  • AW122872 protein
  • BARR2 protein
  • BARRES protein
  • betaarr2 protein
  • zgc:64007 protein

Protein level used designations for Arrestin, beta 2 Proteins (ARRB2)

arrestin beta 2 , arrestin, beta 2 , arrestin 2 , beta-Arrestin 2 , arrestin beta-2 , beta-arrestin-2 , beta-arrestin-2-like , arrestin 3 , arrestin-3 , beta arr2 , beta-arrestin 2 , ARRB2b2

454450 Pan troglodytes
709399 Macaca mulatta
100101741 Xenopus (Silurana) tropicalis
100172117 Pongo abelii
100387113 Callithrix jacchus
100478601 Ailuropoda melanoleuca
100599882 Nomascus leucogenys
409 Homo sapiens
25388 Rattus norvegicus
281638 Bos taurus
216869 Mus musculus
444007 Xenopus laevis
607262 Canis lupus familiaris
100170767 Sus scrofa
100341204 Oryctolagus cuniculus
100072892 Equus caballus
100716149 Cavia porcellus
101112493 Ovis aries
394099 Danio rerio
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