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Human Monoclonal IL7 Primary Antibody for ICFC - ABIN2665850
Melchers, Haasner, Streb, Rolink: B-lymphocyte lineage-committed, IL-7 and stroma cell-reactive progenitors and precursors, and their differentiation to B cells. in Advances in experimental medicine and biology 1993
Show all 3 references for ABIN2665850
Human Monoclonal IL7 Primary Antibody for ICFC - ABIN2661242
Park, Morrissey, Davison, Grabstein: The role of IL-7 and its receptor in B-cell ontogeny. in Advances in experimental medicine and biology 1993
Show all 3 references for ABIN2661242
Human Polyclonal IL7 Primary Antibody for IHC, IHC (p) - ABIN4325437
Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014
increased IL-7 protein production in situ (lung tissue) from non-human primates who received rBCG vaccination, which was associated with increased survival.
These results reveal a novel role of IL-7 and IL-15 (show IL15 Antibodies) in maintaining human T cell function, provide an explanation for T cell dysfunction in humanized mice, and have significant implications for in vitro studies with human T cells.
The results show that SNPs in IL7 caused a significant association in this OA Chinese Han population.
IL-7 is capable of enhancing functional T cell activity without causing significant functional inbalance between various T cell subsets.
A compensatory mechanism of IL-7-mediated homeostatic proliferation can restore the inhibitory network of CD24 (show CD24 Antibodies)+Foxp3 (show FOXP3 Antibodies)+Treg cell after anti-CD25 (show IL2RA Antibodies) induction therapy in islet allotransplantation.
In summary, our study demonstrates that IL-7/IL-7R axis promotes the invasion and migration of prostate cancer cells, through activation of AKT (show AKT1 Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway and upregulation of MMP-3 (show MMP3 Antibodies) and MMP-7 (show MMP7 Antibodies) expression
review of role of IL-7 in immunity and its role in the pathogenesis of neoplasia [review]
Indian patients with primary Sjogren's syndrome have higher salivary sL-selectin and IL-7 levels than healthy controls
increased IL-7 was secreted by mesenchymal stem cells (MSC (show MSC Antibodies)) in the bone marrow, which may protect leukemic cells from apoptosis induced by imatinib through JAK1 (show JAK1 Antibodies)/STAT5 (show STAT5A Antibodies) signaling pathway
The results from this study suggested for the first time that miR (show MLXIP Antibodies)-181c was able to negatively regulate the production of proinflammatory cytokines IL-7 and IL-17 (show IL17A Antibodies) in myasthenia gravis patients.
Increase in serum IL-7 is associated with adenoma.
IL-7 responsiveness in RTE is designed to maximize survival at the expense of reduced proliferation, consistent with RTE serving as a subpopulation of T cells rich in diversity but not in frequency.
Expression of IL-7 is beneficial for induction of potent and long-lasting humoral immune responses.
findings support a redundant role for adaptive Th17 cell- and innate gammadeltaT17 cell-derived IL17 (show IL17A Antibodies) in bacteria-induced colon carcinogenesis, stressing the importance of therapeutically targeting the cytokine itself rather than its cellular sources
functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.
continuous IL7 signaling was not required for tumor regression, although LIP of naive CD8 (show CD8A Antibodies)+ T cells is usually regulated by IL7
IL7 represses the follicular helper T cell gene program.
This study uncovers the metabolic mechanisms by which IL-7 tailors the metabolism of memory T cells to promote their longevity and fast response to rechallenge.
IL-7 reduced IRAK-M (show IRAK3 Antibodies) expression and attenuated immune tolerance induced by either LPS (show TLR4 Antibodies) or CpGA
Poly I:C induces IL-7 production, early inflammatory responses, and characteristic pathologies of SS-like dacryoadenitis in non-autoimmune-prone C57BL/6 mice.
Data show that interleukin 7 (IL-7) signaling is a prerequisite for optimal CD4 (show CD4 Antibodies)(+) T cell activation.
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.