Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
The findings of altered lung function and increased AHR (show AHR ELISA Kits) in Htr4-null mice support a causal relationship between genetic variation in HTR4 and pulmonary function identified in human genome-wide association studies.
Our in vivo data using pharmacologic and genetic approaches suggest that 5-HT(4) receptors are not involved in the bronchial hyperresponsiveness to 5-HT (show DDC ELISA Kits) in cigarette smoke-exposed mice
5-HT (show DDC ELISA Kits) system in the small intestine may play a critical role in regulating circadian rhythms through 5-HT3 (show HTR3A ELISA Kits)/5-HT4-receptor activation.
These results suggest a prominent role of 5-HT(4)R in promoting angiogenesis.
Endogenous 5-HT (show DDC ELISA Kits) exerts a dual role in the pathogenesis of indomethacin-induced intestinal lesions: pro-ulcerogenic action via 5-HT3 (show HTR3A ELISA Kits) receptors and anti-ulcerogenic action via 5-HT4 receptors.
This review presented that the 5HT4 RECEPTOR knockout mice show a correlation between 5-HT (show DDC ELISA Kits) firing rate and depressive/resilience phenotypes.
These results show that prenatal stress and reduced 5-HT (show DDC ELISA Kits) levels can alter 5-HT(4)R expression in the developing forebrain and that some 5-HT(4)R splice variants.
This study demonistrated that alternatively spliced multiple transcripts of 5-hydroxytryptamine receptor (show HTR2A ELISA Kits) expression in heart.
Mucosal 5-HT(4) receptor activation can mediate the prokinetic and antinociceptive actions of 5-HT(4)R agonists.
Data indicate that most p11 (show S100A10 ELISA Kits) expressing cells in cerebral cortex, hippocampus, cerebellum, & caudate-putamen express HTR1B (show HTR1B ELISA Kits) or co-express HTR1B (show HTR1B ELISA Kits)/HTR4, suggesting crucial role for p11 (show S100A10 ELISA Kits) in modulating actions of serotonin via these receptor subtypes.
The 5-HT4 receptor seem to be particularly involved in antigen-induced airway hyperresponsiveness(AI-AHR (show AHR ELISA Kits)) to ACh (show FGFR3 ELISA Kits) in guinea-pigs.
Overexpression of G-protein-coupled receptor HTR4 in rod cells affects the glycosylation pattern of coexisting native rhodopsin.
analysis of eight bovine 5-HT receptor (show HTR7 ELISA Kits) subtypes in brain, abomasum, and intestine by real-time RT-PCR
Data suggest that the 5-HT4 receptor is involved in the neurobiological mechanism underlying familial risk for depression, and that lower striatal 5-HT4 receptor binding is associated with increased risk for developing major depression disorder
PDE3A1 and PDE4D3 are integrated into complexes that contain the 5-HT4(b) receptor and may thereby regulate 5-HT4(b) receptor-mediated signaling.
This study demonistrated that 5-hydroxytryptamine (serotonin) receptor 4 regulate memory.
ADAM19 (show Adam19 ELISA Kits) rs1422795 and HTR4 rs11168048 are associated with pulmonary function.
Stimulation of central 5-HT4 receptors is potentially disease-modifying in a transgenic mouse model of Alzheimer's disease.
Taken together, these data suggest a role for HTR4 in lung development, which may at least in part explain the genetic association with lung function.
Our results suggest that HTR4 polymorphisms may not play a major role in the susceptibility for suicidal behavior in subjects with schizophrenia.
Results suggest an important role for the CHRNA5 (show CHRNA5 ELISA Kits)/3 region as a genetic risk factor for airflow obstruction independent of smoking and implicate the HTR4 gene in the etiology of airflow obstruction.
neurogenic excitatory and inhibitory motor responses and role of 5-HT(4) receptors in circular smooth muscle
The identification of nine novel COOH-terminal splice variants of the porcine 5-HT(4) receptor, is reported.
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described.
, 5-hydroxytryptamine receptor 4
, serotonin receptor 4
, serotonin 5-HT4 receptor
, cardiac 5-HT4 receptor
, 5 hydroxytryptamine ( serotonin) receptor 4
, 5-HT4 receptor (two splicing variants L and S)
, serotonin 4A receptor (5-HT4A)