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anti-Rat (Rattus) SRC antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SRC Antibody (supplied by: Log in to see )

Antigen
V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies
  • ASV
  • AW259666
  • c-src
  • c-SRC
  • c-Src
  • C-src1
  • CG7524
  • D-src
  • D-Src64B
  • Dmel\CG7524
  • DmHD-358
  • Dm SRC1
  • dsrc
  • DSrc
  • dSrc
  • Dsrc
  • DSRC64
  • DSrc64
  • Dsrc64
  • Dsrc64B
  • DSrc64B
  • HD-358
  • MRE5
  • p60-Src
  • PP60C-SCR
  • pp60c-src
  • SDR
  • src
  • Src
  • SRC1
  • src1
  • Src1
  • src64
  • Src64
  • SRC 64B
  • src64B
  • src64b
Epitope
pTyr215
74
34
28
28
25
22
17
15
14
13
11
8
6
6
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
391
178
141
21
9
7
7
4
4
2
2
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
348
66
1
Clonality
Polyclonal
Conjugate
This SRC antibody is conjugated to Biotin
19
15
15
14
13
13
3
3
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
335
194
151
35
26
24
23
20
13
6
5
5
2
1
Supplier
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Catalog No. ABIN712333
$ 379.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN712340 IHC (p) WB HRP Rabbit IgG pTyr215 Log in to see Polyclonal
0.00089488085 ABIN1723244 IHC (p) WB Mouse Log in to see 5A18
0.00089488085 ABIN408484 ICC IF IHC (p) IHC WB Rabbit IgG pTyr418 Log in to see Polyclonal
0.00089488085 ABIN738173 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN738180 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN733613 IF (p) IHC (p) WB Rabbit IgG pTyr529 Log in to see Polyclonal
0.00089488085 ABIN712331 IF (p) IHC (p) WB Rabbit IgG pTyr215 Log in to see Polyclonal
0.00089488085 ABIN738171 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-SRC Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 315 Antibodies 139 Antibodies 109 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Intracellular Staining (ICS) 6 Antibodies 6 Antibodies 3 Antibodies
Immunoprecipitation (IP) 20 Antibodies 7 Antibodies 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 28 Antibodies 11 Antibodies 9 Antibodies
Immunohistochemistry (IHC) 151 Antibodies 83 Antibodies 76 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies 23 Antibodies 23 Antibodies
Immunofluorescence (IF) 36 Antibodies

General

Antigen V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies
Epitope pTyr215
(74), (34), (28), (28), (25), (22), (17), (15), (14), (13), (11), (8), (6), (6), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(391), (178), (141), (21), (9), (7), (7), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(348), (66), (1)
Clonality
Polyclonal
Conjugate This SRC antibody is conjugated to Biotin
(19), (15), (15), (14), (13), (13), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(335), (194), (151), (35), (26), (24), (23), (20), (13), (6), (5), (5), (2), (1)
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Product Details anti-SRC Antibody

Target Details SRC Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from mouse Src around the phosphorylation site of Tyr215
Isotype IgG

Target Details SRC

Product Details anti-SRC Antibody Application Details Handling Images back to top
Antigen
Alternative Name Src (SRC Antibody Abstract)
Background

Src (also known as pp60src) is a non receptor Tyrosine Kinase involved in signal transduction in many biological systems and implicated in the development of human tumors. There are two critical phosphorylation sites of tyrosine on Src, tyrosine 418 and tyrosine 529 (referring to human Src sequence). The tyrosine 418 is located in the catalytic domain and is one of the autophosphorylation sites. Full catalytic activity of Src requires phosphorylation of tyrosine 418. The tyrosine 529 is located near the carboxyl terminus of Src and acts as a negative regulator, in that Src is held in the inactive form through an intramolecular interaction between the SH2 domain and the carboxyl terminus when tyrosine 529 is phosphorylated by Csk. This conformation blocks phosphorylation of tyrosine 418 at the catalytic domain, thereby preventing Src activation. When tyrosine 529 is dephosphorylated, tyrosine 418 can be maximally phosphorylated and Src becomes active. Src is a proto oncogene that may play a role in the regulation of embryonic development and cell growth. Mutations in this gene could be involved in the malignant progression of colon cancer. Immunogen: Synthetic peptide (Human) derived from the region of Src that contains tyrosine 529, based on the human sequence. The sequence is conserved in mouse (tyrosine 534), chicken (tyrosine 527) and frog (tyrosine 525).


Synonyms: SRCphospho Y215, ASV, Avian sarcoma virus, c SRC, CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA, cSrc, EC 2.7.10.2, Neuronal CSRC tyrosine specic protein kinase, Neuronal SRC, Oncogene SRC, OTTHUMP00000030931, OTTHUMP00000174476, OTTHUMP00000174477, p60 Src, p60-Src, p60Src, pp60c src, pp60c-src, pp60csrc, Proto oncogene tyrosine protein kinase Src, Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, Protooncogene SRC, protooncogene SRC Rous sarcoma, Src, SRC Oncogene, SRC_HUMAN, SRC1, Tyrosine kinase pp60c src, Tyrosine protein kinase SRC 1, Tyrosine protein kinase SRC1, v src avian sarcoma Schmidt Ruppin A2 viral oncogene homolog, V src sarcoma Schmidt Ruppin A 2 viral oncogene homolog avian, v src sarcoma Schmidt Ruppin A 2 viral oncogene homolog avian, vsrc avian sarcoma Schmidt Ruppin A2 viral oncogene homolog.
Gene ID 6714
Research Area Cancer, Transcription Factors, Tyrosine Kinases, Signaling
Pathways JAK-STAT Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-SRC Antibody Target Details SRC Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only

Handling

Product Details anti-SRC Antibody Target Details SRC Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at 4°C
Expiry Date 12 months