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Browse our anti-STAT1 (STAT1) Antibodies

Full name:
anti-Signal Transducer and Activator of Transcription 1, 91kDa Antibodies (STAT1)
On www.antibodies-online.com are 604 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies from 37 different suppliers available. Additionally we are shipping STAT1 Kits (46) and STAT1 Proteins (21) and many more products for this protein. A total of 715 STAT1 products are currently listed.
Synonyms:
2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, H2RSP, IMUP, IMUP-1, IMUP-2, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, STAT4, STAT91, XStat1
list all antibodies Gene Name GeneID UniProt
STAT1 72275  
STAT1 25124  
STAT1 6772 P42224

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Top referenced anti-STAT1 Antibodies

  1. Human Polyclonal STAT1 Primary Antibody for EIA, IHC (p) - ABIN358231 : Garcin, Marq, Iseni, Martin, Kolakofsky: A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability. in Journal of virology 2004 (PubMed)
    Show all 5 references for ABIN358231

  2. Human Polyclonal STAT1 Primary Antibody for EIA, IF - ABIN500815 : Leonard, OShea: Jaks and STATs: biological implications. in Annual review of immunology 1998 (PubMed)
    Show all 4 references for ABIN500815

  3. Cow (Bovine) Polyclonal STAT1 Primary Antibody for WB - ABIN2777895 : Battle, Lynch, Frank: Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. in Cancer research 2006 (PubMed)
    Show all 2 references for ABIN2777895

  4. Human Monoclonal STAT1 Primary Antibody for IHC (p), IP - ABIN269146 : Kovarik, Boudny, Kocak, Lauerova, Fait, Vagundova: Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. in International journal of molecular medicine 2003 (PubMed)
    Show all 2 references for ABIN269146

  5. Human Polyclonal STAT1 Primary Antibody for IF, IHC - ABIN1533008 : Durbin, Hackenmiller, Simon, Levy: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. in Cell 1996 (PubMed)
    Show all 2 references for ABIN1533008

  6. Human Polyclonal STAT1 Primary Antibody for ELISA, WB - ABIN1533729 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

More Antibodies against STAT1 Interaction Partners

Mouse (Murine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. IFN-I can mediate ISG expression inmixed glial cell cultures (MGCs) via ISGF3 (show IRF9 Antibodies)-independent signaling pathways but with reduced efficiency, with delayed and prolonged kinetics, and is more dependent on STAT1 and STAT2 (show STAT2 Antibodies) than IRF9 (show IRF9 Antibodies); and 2) signaling pathways not involving STAT1, STAT2 (show STAT2 Antibodies), or IRF9 (show IRF9 Antibodies) play a minor role only in mediating IFN-alpha (show IFNA Antibodies)-stimulated genes expression in MGCs.

  2. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (show ULK1 Antibodies) expression and autophagy.

  3. a novel negative feedback loop mediated by STAT3 (show STAT3 Antibodies)-SOCS3 (show SOCS3 Antibodies), which is tightly controlled by SENP1 (show SENP1 Antibodies) via de-SUMOylation of protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Antibodies)), in IFN-gamma (show IFNG Antibodies) signaling, is reported.

  4. In a mouse model of spontaneous osteopenia caused by hyperactivation of STAT1/3 signaling downstream of gp130 (gp130 (show LRPPRC Antibodies)(Y757F/Y757F)), STAT1 deletion rescued the osteopenic phenotype, indicating a beneficial effect of promoting STAT3 (show STAT3 Antibodies) signaling over STAT1 downstream of gp130 (show LRPPRC Antibodies) in this low bone mass condition, and this may have therapeutic value.

  5. this study shows that STAT-1 and STAT-3 (show STAT3 Antibodies) interplay to regulate indoleamine 2,3-dioxygenase activity and immunosuppression in response to of IL-27 (show IL27 Antibodies) in neonatal macrophages

  6. this study shows that binding motifs for the transcription factors STAT1 and IRF1 (show IRF1 Antibodies) are associated with robust and IL-4 (show IL4 Antibodies)-resistant responses to IFN-gamma (show IFNG Antibodies) in macrophages

  7. Study showed that suppression of STAT3 (show STAT3 Antibodies), STAT5 (show STAT5A Antibodies), and STAT6 (show STAT6 Antibodies) and overexpression of the proapoptotic factor STAT1, which provides p53 (show TP53 Antibodies)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (show ERBB2 Antibodies) tyrosine kinase receptor (show KDR Antibodies) overexpression promotes neuronal survival through activation of STAT-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1

  8. STAT signaling plays a central role during retinal degeneration in the rd10 (show PDE6B Antibodies) mouse model.

  9. Donor interleukin-22 (show IL22 Antibodies) and host type I interferon (show IFNA Antibodies) signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10 (show CXCL10 Antibodies).

  10. OGG1 (show OGG1 Antibodies) acts as a STAT1 coactivator and has transcriptional activity in the presence of endotoxin

Human Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. the dual regulation of STAT1 by IKKalpha (show CHUK Antibodies) in antiviral signaling suggests a role for IKKalpha (show CHUK Antibodies) in the fine-tuning of antiviral signaling in response to non-self RNA.

  2. This study demonstrated the first coiled-coil domain mutation of STAT1 as a genetic cause of autosomal-dominant Mendelian susceptibility to mycobacterial diseases

  3. STAT1 suppression by S100A6 (show S100A6 Antibodies) may represent a promising therapeutic target to facilitate reendothelialization in damaged vessels.

  4. Our data demonstrate an important connection between mRNA translation and KRAS tumorigenesis under the control of STAT1, which can determine the susceptibility of KRAS tumors to pharmacologic inhibition of mRNA translation initiation.

  5. study demonstrated that miR (show MLXIP Antibodies)-9 could inhibit activation of the NLRP3 (show NLRP3 Antibodies) inflammasome and attenuate atherosclerosis-related inflammation, likely through the JAK1 (show JAK1 Antibodies)/STAT1 signaling pathway. Therefore, miR (show MLXIP Antibodies)-9 may serve as a potential therapeutic target for atherosclerosis.

  6. the deubiquitinase USP2a translocates into the nucleus and binds to pY701-STAT1, and inhibits K48-linked ubiquitination and degradation of pY701-STAT1

  7. Demonstrate STAT1-dependent transcriptional activation of TLR8 (show TLR8 Antibodies) with estrogen stimulation.

  8. STAT1 binding sites were identified on the putative miR-7 (show LILRB1 Antibodies) promoter and stimulation of fibroblasts with the inflammatory cytokine, interferon-gamma (IFN-gamma (show IFNG Antibodies)), significantly increased miR-7 (show LILRB1 Antibodies) transcriptional activity and resulted in upregulated miR-7 (show LILRB1 Antibodies) and loss of EGFR (show EGFR Antibodies).

  9. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (show ULK1 Antibodies) expression and autophagy.

  10. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (show GBP1 Antibodies), TLR3 (show TLR3 Antibodies), OAS1 (show OAS1 Antibodies), EIF2AK2 (show EIF2AK2 Antibodies), HLA-E (show HLAE Antibodies), IFI6 (show IFI6 Antibodies), and STAT1, showed higher expression in the islet core compared with the peri (show PLIN1 Antibodies)-islet area containing the surrounding immune cells.

Pig (Porcine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (show IFNA Antibodies) response by inducing STAT1 degradation.

  2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets

  3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (show JAK3 Antibodies)-STAT1) signaling pathway.

  4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (show STAT2 Antibodies) nuclear translocation.

  5. Nsp1beta inhibits interferon-activated (show MNDA Antibodies) STAT1/STAT2 (show STAT2 Antibodies) signal transduction by inducing karyopherin-alpha1 degradation.

  6. STAT1 is involved in mediating the action of ghrelin (show GHRL Antibodies) on ovarian cell functions.

  7. the majority of the STAT1/STAT2 (show STAT2 Antibodies)/IRF9 (show IRF9 Antibodies) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked

  8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.

  9. Nitric oxide-dependent increase in caspase-8 (show CASP8 Antibodies) mRNA levels is associated with phosphorylation of STAT-1 at Ser (show SIGLEC1 Antibodies)-727 and STAT1 binding to the caspase-8 (show CASP8 Antibodies) promoter in cultured lung endothelial cells.

  10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.

Cow (Bovine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Report interferon-tau dependent STAT1 regulation of SOCS (show CISH Antibodies) genes in bovine endometrium during estrus cycle and embryo implantation.

  2. the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate

  3. results show for the first time that interleukin-6 (show IL6 Antibodies) (IL), in the presence of its soluble receptor (show IFNAR1 Antibodies) (sIL (show STIL Antibodies)-6R), induces activation of JAK1 (show JAK1 Antibodies), JAK2 (show JAK2 Antibodies), and STAT1/STAT3 (show STAT3 Antibodies) proteins in bovine articular chondrocytes

  4. Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (show CSN2 Antibodies) synthesis and fat metabolism.

  5. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (show STAT2 Antibodies).

STAT1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT1

  • signal transducer and activator of transcription 1, 91kDa (STAT1) antibody
  • RIKEN cDNA 2200002D01 gene (2200002D01Rik) antibody
  • signal transducer and activator of transcription 1 (Stat1) antibody
  • signal transducer and activator of transcription 1, 91kDa (stat1) antibody
  • signal transducer and activator of transcription 4 (stat4) antibody
  • 2010005J02Rik antibody
  • AA408197 antibody
  • CANDF7 antibody
  • DD6G4-4 antibody
  • dZ182H3.3 antibody
  • H2RSP antibody
  • IMUP antibody
  • IMUP-1 antibody
  • IMUP-2 antibody
  • ISGF-3 antibody
  • si:by51f19.1 antibody
  • si:by134g18.2 antibody
  • si:dz73o4.2 antibody
  • si:dz182h3.3 antibody
  • si:dz199m19.1 antibody
  • STAT antibody
  • STAT1 antibody
  • STAT4 antibody
  • STAT91 antibody
  • XStat1 antibody

Protein level used designations for STAT1

signal transducer and activator of transcription 1-alpha/beta , HAI-2 related small protein , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 4 , signal transducer and activator of transcription 1 , transcription factor ISGF-3 , activator of transcription , signal transduction

GENE ID SPECIES
100307049 Ovis aries
72275 Mus musculus
20846 Mus musculus
25124 Rattus norvegicus
6772 Homo sapiens
424044 Gallus gallus
488449 Canis lupus familiaris
396655 Sus scrofa
510814 Bos taurus
398324 Xenopus laevis
100343893 Oryctolagus cuniculus
368519 Danio rerio
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