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Browse our anti-STAT6 (STAT6) Antibodies

Full name:
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced Antibodies (STAT6)
On www.antibodies-online.com are 433 Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antibodies from 36 different suppliers available. Additionally we are shipping STAT6 Kits (43) and STAT6 Proteins (15) and many more products for this protein. A total of 506 STAT6 products are currently listed.
Synonyms:
D12S1644, IL-4-STAT, STAT6B, STAT6C
list all antibodies Gene Name GeneID UniProt
STAT6 20852 P52633
STAT6 6778 P42226
STAT6 362896  

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Top referenced anti-STAT6 Antibodies

  1. Human Monoclonal STAT6 Primary Antibody for IF, WB - ABIN968455 : Bartoli, Gu, Tsai, Venema, Brooks, Marrero, Caldwell: Vascular endothelial growth factor activates STAT proteins in aortic endothelial cells. in The Journal of biological chemistry 2000 (PubMed)
    Show all 9 references for ABIN968455

  2. Mouse (Murine) Monoclonal STAT6 Primary Antibody for ICS - ABIN1177230 : Daley, Brancato, Thomay, Reichner, Albina: The phenotype of murine wound macrophages. in Journal of leukocyte biology 2010 (PubMed)
    Show all 4 references for ABIN1177230

  3. Mouse (Murine) Monoclonal STAT6 Primary Antibody for ICS - ABIN1177232 : Hale, Krutzik, Samra, Crane, Nolan: Stage dependent aberrant regulation of cytokine-STAT signaling in murine systemic lupus erythematosus. in PLoS ONE 2009 (PubMed)
    Show all 2 references for ABIN1177232

  4. Human Polyclonal STAT6 Primary Antibody for IHC, ELISA - ABIN1533015 : Hou, Schindler, Henzel, Ho, Brasseur, McKnight: An interleukin-4-induced transcription factor: IL-4 Stat. in Science (New York, N.Y.) 1994 (PubMed)
    Show all 2 references for ABIN1533015

  5. Human Polyclonal STAT6 Primary Antibody for IF, IHC - ABIN1533014 : Takeda, Tanaka, Shi, Matsumoto, Minami, Kashiwamura, Nakanishi, Yoshida, Kishimoto, Akira: Essential role of Stat6 in IL-4 signalling. in Nature 1996 (PubMed)
    Show all 2 references for ABIN1533014

  6. Mouse (Murine) Monoclonal STAT6 Primary Antibody for ICS - ABIN1177231 : Mikita, Campbell, Wu, Williamson, Schindler: Requirements for interleukin-4-induced gene expression and functional characterization of Stat6. in Molecular and cellular biology 1996 (PubMed)

  7. Cow (Bovine) Polyclonal STAT6 Primary Antibody for IHC, WB - ABIN2777200 : Li, Yang, Li, Yuan, Liu, Yuan, Zhang: IL-4/Stat6 activities correlate with apoptosis and metastasis in colon cancer cells. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against STAT6 Interaction Partners

Mouse (Murine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. These studies are the first to demonstrate that gammadelta17 cells express the type I IL-4 (show IL4 Antibodies) receptor and that STAT6 signaling negatively regulates gammadelta17 cells, a cell population that plays a front-line role in mucosal immunity.

  2. this study identifies proteins in B cells that are regulated by IL-4 in a STAT6-dependent manner, which may contribute to germinal center formation and IgE switching in type 2 immunity

  3. Study showed that suppression of STAT3 (show STAT3 Antibodies), STAT5 (show STAT5A Antibodies), and STAT6 and overexpression of the proapoptotic factor STAT1 (show STAT1 Antibodies), which provides p53 (show TP53 Antibodies)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (show ERBB2 Antibodies) tyrosine kinase receptor (show KDR Antibodies) overexpression promotes neuronal survival through activation of STAT (show STAT1 Antibodies)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (show STAT1 Antibodies)

  4. STAT6 mediates the CT-induced TIM4 (show TIMD4 Antibodies) expression in DCs. In conclusion, p300 (show NOTCH1 Antibodies) and STAT6 mediate the microbial product CT-induced TIM4 (show TIMD4 Antibodies) expression in DCs.

  5. These data demonstrate that dysregulated IL-25 (show IL25 Antibodies) expression contributes to lipid accumulation, whereas exogenous IL-25 (show IL25 Antibodies) protects against hepatic steatosis through IL-13 (show IL13 Antibodies) activation of STAT6.

  6. Grail (show RNF128 Antibodies) interacts with Stat6 and targets it for ubiquitination and degradation in Th2 cells.

  7. The lack of STAT6 did not affect the ability of macrophages to change cytokine production reciprocally or to rescue mice from lethal endotoxemia.

  8. both in vivo and in vitro experiments demonstrate that the transcription factors STAT6 and KLF4 (show KLF4 Antibodies) implement IL-4 (show IL4 Antibodies)-induced M2 polarization via the dual catalytic activities of MCPIP (show ZC3H12A Antibodies).

  9. Th2 immunity mediated by STAT6 appears to play a protective role in a murine model of prurigo

  10. Data suggest that transcription factor STAT6 regulates the recruitment of eosinophils to the lung during the development of allergic asthma.

Human Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. STAT6-TMEM16A (show ANO1 Antibodies)-ERK1/2 (show MAPK1/3 Antibodies) signal pathway and TMEM16A (show ANO1 Antibodies) channel activity are required for the IL-13 (show IL13 Antibodies)-induced TMEM16A (show ANO1 Antibodies) mediated mucus production

  2. The detection of nuclear relocation of STAT6 with immunohistochemistry is a characteristic of solitary fibrous tumours (SFTs), and may serve as a diagnostic marker that indicates NAB2 (show NAB2 Antibodies)-STAT6 fusion and helps to discriminate SFTs from histological mimics.

  3. The role of Th2 cytokines (IL-4 (show IL4 Antibodies), IL-13 (show IL13 Antibodies)) and STAT6 in Th1 (show TH1L Antibodies)/Th2 imbalance.

  4. STAT6 gene (G2964) polymorphism may play a role in development of eczema among Saudi children

  5. Variants of the NAB2 (show NAB2 Antibodies)-STAT6 fusion gene are found in solitary fibrous tumors of the meninges.

  6. the majority of intrathoracic SFTs exhibited STAT6 nuclear staining, and NAB2ex4-STAT6ex2/3 was the predominant fusion type.

  7. Case Report: NAB2 (show NAB2 Antibodies)-STAT6 fusion in glioblastoma.

  8. A constitutively activated form of STAT6 is able to bypass IL-4 (show IL4 Antibodies) upstream signalling and instruct dendritic-cell-specific functional DNA methylation (show HELLS Antibodies) changes

  9. interleukin-4 (show IL4 Antibodies) regulates hematopoietic lineage choice by activating the JAK3 (show JAK3 Antibodies)-STAT6 pathway, which causes dendritic-cell-specific DNA demethylation

  10. Immunohistochemistry results indicate that combination with ALDH1 (show ALDH1A1 Antibodies) and STAT6 can improve the diagnostic value of CD34 (show CD34 Antibodies) for solitary fibrous tumors.

Pig (Porcine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. this study shows that weaning caused severe inflammation associated with the suppression of STAT6 in the jejunum of piglets

  2. Data show that IL-4 (show IL4 Antibodies) induces upregulation of the junction protein claudin-5 (show CLDN5 Antibodies) in endothelial cells (ECs) through activation of Jak (show JAK3 Antibodies)/STAT6 and phosphorylation and translocation of FoxO1 (show FOXO1 Antibodies) from the nucleus to the cytoplasm.

Cow (Bovine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. Results provide evidence that polymorphisms in STAT6 are associated with carcass and growth efficiency traits

Guinea Pig Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. IL-4 (show IL4 Antibodies) and STAT6 are related to the pathogenesis of allergic rhinitis and may be the main factors for eosinophil infiltration in allergic rhinitis.

STAT6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with STAT6

  • signal transducer and activator of transcription 6, interleukin-4 induced (STAT6) antibody
  • signal transducer and activator of transcription 6 (Stat6) antibody
  • signal transducer and activator of transcription 6-like (LOC100859543) antibody
  • signal transducer and activator of transcription 6, interleukin-4 induced (Stat6) antibody
  • D12S1644 antibody
  • IL-4-STAT antibody
  • STAT6B antibody
  • STAT6C antibody

Protein level used designations for STAT6

signal transducer and transcription activator 6 , STAT, interleukin4-induced , signal transducer and activator of transcription 6 , transcription factor IL-4 STAT

GENE ID SPECIES
100050053 Equus caballus
20852 Mus musculus
100859543 Gallus gallus
6778 Homo sapiens
100142679 Canis lupus familiaris
362896 Rattus norvegicus
100153518 Sus scrofa
353105 Bos taurus
100344264 Oryctolagus cuniculus
100726686 Cavia porcellus
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