anti-Rat (Rattus) STAT6 antibody for Immunohistochemistry

Recommended STAT6 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antibodies
  • D12S1644
  • IL-4-STAT
  • STAT6B
  • STAT6C
  • signal transducer and activator of transcription 6, interleukin-4 induced
  • signal transducer and activator of transcription 6
  • signal transducer and activator of transcription 6-like
  • STAT6
  • Stat6
  • LOC100859543
Epitope
C-Term
80
39
19
17
15
15
12
11
11
7
5
5
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
413
186
131
24
19
16
14
14
8
5
3
2
1
1
1
Host
Rabbit
269
169
6
1
1
Clonality
Polyclonal
Conjugate
This STAT6 antibody is un-conjugated
16
15
14
14
12
10
7
7
6
5
5
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
3
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
325
148
126
64
50
42
39
38
32
11
5
4
3
3
1
1
1
1
1
1
Options
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Catalog No. ABIN2780481
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.754329 ABIN2777200 IHC WB Rabbit C-Term Log in to see Polyclonal 1
9.754329 ABIN1531979 IHC ELISA WB Rabbit IgG pThr645 Log in to see Polyclonal 1
9.754329 ABIN1531980 IHC ELISA WB Rabbit IgG pTyr641 Log in to see Polyclonal 1
9.754329 ABIN1533015 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 2
9.754329 ABIN1533014 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 2
1 ABIN3187093 ELISA IHC IP WB Rabbit IgG Tyr125 Log in to see Polyclonal
1 ABIN3182155 ELISA IHC WB Rabbit IgG pTyr641 Log in to see Polyclonal
1 ABIN3182154 ELISA IHC IP WB Rabbit IgG pThr645 Log in to see Polyclonal
1 ABIN2889071 ELISA IHC WB Rabbit IgG AA 608-657 Log in to see Polyclonal
1 ABIN2889070 ELISA IHC IP WB Rabbit IgG AA 612-661 Log in to see Polyclonal
1 ABIN1874970 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN3187092 ELISA IHC WB Rabbit IgG Tyr125 Log in to see Polyclonal
1 ABIN1860656 ICC IHC IP WB Rabbit IgG AA 557-841 Log in to see Polyclonal
1 ABIN4356445 ICC IF IHC IHC (p) SimWes WB Rabbit IgG Log in to see Polyclonal
1 ABIN1585293 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1845138 IP IHC WB Rabbit pThr645 Log in to see Polyclonal
1 ABIN1092395 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1092396 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1845134 IHC WB Rabbit pTyr641 Log in to see Polyclonal
1 ABIN4356444 ICC IF IHC IHC (p) SimWes WB Rabbit IgG Log in to see Polyclonal

Similar anti-STAT6 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Cow (Bovine) Rabbit Guinea Pig Horse (Equine)
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 2 Antibodies 2 Antibodies
Simple Western (SimWes) 3 Antibodies 2 Antibodies 2 Antibodies
Western Blotting (WB) 308 Antibodies 140 Antibodies 17 Antibodies 89 Antibodies 12 Antibodies 12 Antibodies 5 Antibodies 7 Antibodies
Intracellular Staining (ICS) 8 Antibodies 2 Antibodies 5 Antibodies 2 Antibodies
Immunoprecipitation (IP) 40 Antibodies 31 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antibodies
Epitope C-Term
(80), (39), (19), (17), (15), (15), (12), (11), (11), (7), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(413), (186), (131), (24), (19), (16), (14), (14), (8), (5), (3), (2), (1), (1), (1)
Host Rabbit
(269), (169), (6), (1), (1)
Clonality
Polyclonal
Conjugate This STAT6 antibody is un-conjugated
(16), (15), (14), (14), (12), (10), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(325), (148), (126), (64), (50), (42), (39), (38), (32), (11), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-STAT6 Antibody

Target Details STAT6 Application Details Handling ProductDetails: References for anti-STAT6 antibody (ABIN2780481) Images
Blocking Peptide Blocking peptide for this product available: ABIN984538
Sequence TEQDLTKLLL EGQGESGGGS LGAQPLLQPS HYGQSGISMS HMDLRANPSW
Predicted Reactivity Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against STAT6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human STAT6

Target Details STAT6

Product Details anti-STAT6 Antibody Application Details Handling ProductDetails: References for anti-STAT6 antibody (ABIN2780481) Images back to top
Antigen
Alternative Name STAT6 (STAT6 Antibody Abstract)
Background STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
Alias Symbols: D12S1644, IL-4-STAT, STAT6B, STAT6C
Protein Interaction Partner: UBC, IRF4, PDE12, EHD1, USP8, API5, PGGT1B, EP300, TRIM28, JAK3, RCN3, LITAF, IL4R, EEF1A1, VKORC1, PTPN2, STAT2, JAK1, IFNG, IFNAR1, SRXN1, PSAT1, DSTN, SEC24A, AHCYL1, SSSCA1, NUBP2, SH3BGRL, RAD23B, PPM1G, IGBP1, CEBPE, SND1, SUMO2, FCER2, SFPQ, IGHE,
Protein Size: 847
Molecular Weight 94 kDa
Gene ID 6778
NCBI Accession NM_003153, NP_003144
UniProt P42226
Research Area Chromatin and Nuclear Signaling, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-STAT6 Antibody Target Details STAT6 Handling ProductDetails: References for anti-STAT6 antibody (ABIN2780481) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 847 AA

Restrictions For Research Use only

Handling

Product Details anti-STAT6 Antibody Target Details STAT6 Application Details ProductDetails: References for anti-STAT6 antibody (ABIN2780481) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-STAT6 antibody (ABIN2780481)

Product Details anti-STAT6 Antibody Target Details STAT6 Application Details Handling Images back to top
Background publications

Blanchard, Durual, Estienne, Emami, Vasseur, Cuber: "Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13 via the signal transducer and activator of transcription 6." in: The international journal of biochemistry & cell biology, Vol. 37, Issue 12, pp. 2559-73, 2005

Images

Product Details anti-STAT6 Antibody Target Details STAT6 Application Details Handling ProductDetails: References for anti-STAT6 antibody (ABIN2780481) back to top
Supplier Images
Western Blotting (WB) image for anti-STAT6 antibody (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced) (C-Term) (ABIN2780481) anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibody
Immunohistochemistry (IHC) image for anti-STAT6 antibody (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced) (C-Term) (ABIN2780481) anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibody (Image 2)