Browse our anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Antibodies

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anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Antibodies (PPP1CA)
On www.antibodies-online.com are 125 Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Antibodies from 24 different suppliers available. Additionally we are shipping Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Proteins (14) and Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Kits (8) and many more products for this protein. A total of 154 Protein Phosphatase 1, Catalytic Subunit, alpha Isoform products are currently listed.
Synonyms:
2310003C21Rik, 2900017D14Rik, AI427932, AU017636, dism2, MMPa-2, MPPa-1, PP-1A, PP1A, PP1alpha, PP2C-ALPHA, PP2CA, PP2Calpha, PPP1A, Ppp1c, wu:fc04c08, wu:fc09b07, wu:fc30g11, wu:fe05h08, zgc:85729
list all antibodies Gene Name GeneID UniProt
PPP1CA 19045 P62137
PPP1CA 5499 P62136
PPP1CA 24668 P62138

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Most Popular Reactivities for anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Antibodies

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All available anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Antibodies

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Top referenced anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Antibodies

  1. Human Monoclonal PPP1CA Primary Antibody for ELISA, WB - ABIN969360 : Chen, Kesler, Paschal, Balk: Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for 969360

  2. Human Monoclonal PPP1CA Primary Antibody for ELISA, WB - ABIN969359 : Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. in The EMBO journal 2007 (PubMed)
    Show all 2 references for 969359

  3. Human Monoclonal PPP1CA Primary Antibody for IF, WB - ABIN1108708 : Barker, Jones, da Cruz e Silva, Spurr, Sheer, Cohen: Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13. in Genomics 1990 (PubMed)
    Show all 2 references for 1108708

  4. Human Monoclonal PPP1CA Primary Antibody for EIA, IHC (p) - ABIN238369 : Cohen: Protein phosphatase 1--targeted in many directions. in Journal of cell science 2002 (PubMed)
    Show all 2 references for 238369

  5. Human Polyclonal PPP1CA Primary Antibody for IHC, ELISA - ABIN1531470 : Song, Khanna, Lu, Lavin: Cloning and characterization of a human protein phosphatase 1-encoding cDNA. in Gene 1993 (PubMed)

  6. Cow (Bovine) Polyclonal PPP1CA Primary Antibody for WB - ABIN2787782 : Lesage, Beullens, Pedelini, Garcia-Gimeno, Waelkens, Sanz, Bollen: A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3. in Biochemistry 2007 (PubMed)

More Antibodies against Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) interaction partners

  1. Data, including data from studies using transgenic/knockout mice, suggest that Ppp1ca and Gnb1 (show GNB1 Antibodies) interact in quiescent platelets; then, Ppp1ca and Plcb3 (show PLCB3 Antibodies) interact during platelet aggregation; thus, Gnb1 (show GNB1 Antibodies) enlists Ppp1ca to modulate G protein-coupled receptor (show GPR34 Antibodies) signaling. (Ppp1ca = protein phosphatase 1 (show PPP1CB Antibodies), catalytic subunit alpha; Gnb1 (show GNB1 Antibodies) = guanine nucleotide-binding protein (show TRIM23 Antibodies), subunit beta-1; Plcb3 (show PLCB3 Antibodies) = phospholipase C (show PLC Antibodies), subunit beta-3)

  2. findings demonstrate a novel regulatory circuit in which STING and TBK1 (show TBK1 Antibodies) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (show PPM1A Antibodies) dephosphorylates STING and TBK1 (show TBK1 Antibodies)

  3. the studies presented here position PPM1A (show PPM1A Antibodies) as a new player in the wound healing-inflammation-angiogenesis axis in mouse, reveal its crucial role in homeostasis on injury, and highlight its potential as a therapeutic mediator in pathologic conditions

  4. Ang (show ANG Antibodies) IV functions via regulating the activity of PP1 (show PPP1CC Antibodies)

  5. a nuclear envelope-localized mechanism of inactivating TGF-beta (show TGFB1 Antibodies) signaling in which MAN1 (show LEMD3 Antibodies) competes with transcription factors for binding to Smad2 (show SMAD2 Antibodies) and Smad3 (show SMAD3 Antibodies) and facilitates their dephosphorylation by PPM1A (show PPM1A Antibodies).

  6. Although a non-myristoylated mutation (G2A (show GPR132 Antibodies)) of PPM1A (show PPM1A Antibodies) and PPM1B (show PPM1B Antibodies) prevented membrane association, this relocalization did not likely cause the decreased activity towards AMPKalpha (show GRK4 Antibodies).

  7. we found that PPM1A (show PPM1A Antibodies) mRNA is synthesized at the beginning of the maturation process and remains elevated in the mature oocytes, promoting the accumulation of PPM1A (show PPM1A Antibodies) protein

  8. Cell surface expression of the major amyloid-beta peptide (Abeta (show APP Antibodies))-degrading enzyme, neprilysin (show MME Antibodies), depends on phosphorylation by mitogen-activated protein kinase (show MAPK1 Antibodies)/extracellular signal-regulated kinase kinase (MEK (show MDK Antibodies)) and dephosphorylation by protein phosphatase 1a (show PPM1A Antibodies).

  9. analysis of selective regulation of NR2B (show GRIN2B Antibodies) by protein phosphatase-1 (show PPP1CB Antibodies) for the control of the NMDA receptor in neuroprotection

  10. Protein phosphatase PPM1A (show PPM1A Antibodies) regulates the nuclear export of Smad2 (show SMAD2 Antibodies)/3 through targeting nuclear exporter RanBP3 (show RANBP3 Antibodies).

Human Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) interaction partners

  1. establish PPM1A (show PPM1A Antibodies) as a novel repressor of the SMAD3 (show SMAD3 Antibodies) pathway in renal fibrosis

  2. Data, including data from studies using cells from knockout mice, suggest that gasotransmitter H(2)S up-regulates eIF2a (show EIF2S1 Antibodies) phosphorylation by inhibiting PPP1CA via persulfidation, which in turn leads to transient suppression of global translation and activation of Atf4 (show ATF4 Antibodies) expression. (eIF2a (show EIF2S1 Antibodies) = eukaryotic initiation factor-2alpha (show EIF2S1 Antibodies); PPP1CA = protein phosphatase 1 catalytic subunit alpha; Atf4 (show ATF4 Antibodies) = activating transcription factor 4 (show ATF4 Antibodies))

  3. Report a tumor-suppressive function of PPM1A (show PPM1A Antibodies) and an independent relationship to Smad4 (show SMAD4 Antibodies) in pancreatic ductal adenocarcinoma.

  4. Protein phosphatase 1 (show PPP1CB Antibodies) (PP1 (show PPA1 Antibodies)) forms stable complexes with PP1 (show PPA1 Antibodies)-interacting proteins (PIPs (show GPRASP1 Antibodies)) that guide the phosphatase throughout its life cycle and control its fate and function.

  5. The authors found that RNA recognition motif 1 (RRM1 (show RRM1 Antibodies)) in SRSF1 (show SRSF1 Antibodies) binds PP1 (show PPA1 Antibodies) and represses its catalytic function through an allosteric mechanism.

  6. this study shows a pivotal role for PP1 (show PPA1 Antibodies) in impeding IRF7 (show IRF7 Antibodies)-mediated IFN-alpha (show IFNA Antibodies) production in host immune responses

  7. hydrogen/deuterium exchange-mass spectrometry and molecular dynamics to characterize conformational changes in PP2Calpha (show PPM1A Antibodies) between the active and inactive states

  8. In a nested case control study of ischemic stroke, there was an epigenome-wide association for cg04985020 (PPM1A (show PPM1A Antibodies); P=1.78x10(-07)) with vascular recurrence in patients treated with aspirin.

  9. The data support a model where Cdc7 (show CDC7 Antibodies) (de)phosphorylation is the molecular switch for the activation and inactivation of DNA replication in mitosis, directly connecting Cdc7 (show CDC7 Antibodies) and PP1a/Cdk1 (show CDK1 Antibodies) to the regulation of once-per-cell cycle DNA replication in mammalian cells.

  10. These results indicate that PP1 (show PPA1 Antibodies) is recruited to the extracellular calcium-dependent E-cadherin (show CDH1 Antibodies)-catenin-PIP5K1a (show PIP5K1A Antibodies) complex in the plasma membrane to activate PIP5K1a (show PIP5K1A Antibodies), which is required for PLC (show HSPG2 Antibodies)-g1 activation leading to keratinocyte differentiation.

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA)

  • protein phosphatase 1, catalytic subunit, alpha isozyme (ppp1ca) antibody
  • protein phosphatase 1, catalytic subunit, alpha isozyme (PPP1CA) antibody
  • protein phosphatase 1, catalytic subunit, alpha isoform (Ppp1ca) antibody
  • protein phosphatase 1, catalytic subunit, alpha isoform a (ppp1caa) antibody
  • protein phosphatase 1, catalytic subunit, alpha isozyme (Ppp1ca) antibody
  • protein phosphatase 1, catalytic subunit, beta isozyme (Ppp1cb) antibody
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (PPM1A) antibody
  • 2310003C21Rik antibody
  • 2900017D14Rik antibody
  • AI427932 antibody
  • AU017636 antibody
  • dism2 antibody
  • MMPa-2 antibody
  • MPPa-1 antibody
  • PP-1A antibody
  • PP1A antibody
  • PP1alpha antibody
  • PP2C-ALPHA antibody
  • PP2CA antibody
  • PP2Calpha antibody
  • PPP1A antibody
  • Ppp1c antibody
  • wu:fc04c08 antibody
  • wu:fc09b07 antibody
  • wu:fc30g11 antibody
  • wu:fe05h08 antibody
  • zgc:85729 antibody

Protein level used designations for PPP1CA

Protein phosphatase type 1 alpha, catalytic subunit , protein phosphatase 1, catalytic subunit, alpha isoform , PP-1A , serine/threonine-protein phosphatase PP1-alpha catalytic subunit , ppp1ca , protein phosphatase 1, catalytic subunit, alpha , serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit , protein phosphatase-1d , PP-1B , protein phosphatase 1, catalytic subunit, beta isoform , protein phosphatase-1a , serine/threonine-protein phosphatase PP1-beta catalytic subunit , Mpp alpha , PP2C-alpha , protein phosphatase 1A , protein phosphatase 2C isoform alpha , protein phosphatase IA , protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform , IA , protein phosphatase 2C alpha

GENE ID SPECIES
379914 Xenopus laevis
745709 Pan troglodytes
100059233 Equus caballus
100145598 Xenopus (Silurana) tropicalis
19045 Mus musculus
407980 Danio rerio
5499 Homo sapiens
24668 Rattus norvegicus
516175 Bos taurus
403609 Canis lupus familiaris
100009298 Oryctolagus cuniculus
25594 Rattus norvegicus
19042 Mus musculus
5494 Homo sapiens
281994 Bos taurus
100009431 Oryctolagus cuniculus
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