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Rat (Rattus) ERK2 ELISA Kit for Sandwich ELISA - ABIN431451
Kiasalari, Baluchnejadmojarad, Roghani: Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease. in Cellular and molecular neurobiology 2016
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MKP1 (show DUSP1 ELISA Kits) is a negative regulator of signaling pathways required for some, but not all, early and late pathogen-associated molecular pattern responses.
MKP1 (show DUSP1 ELISA Kits) and PTP1 act redundantly to suppress salicylic acid and camalexin biosynthesis, and regulate growth homeostasis and PR gene expression in an MPK3 (show MAPK3 ELISA Kits)- and MPK6 (show MAPK6 ELISA Kits)-dependent manner.
Regulation of AtMPK1/2 kinase activity in Arabidopsis might be under the control of signals involved in different kinds of stress.
AtMKP2, a novel MKP protein in Arabidopsis, acts upon MPK3 (show MAPK3 ELISA Kits) and -6, and serves as a positive regulator of the cellular response to oxidant challenge
The present results suggest that demecolcine might contribute to the activation of the Mos (show MOCOS ELISA Kits)/MAPK pathway and affect spindle structure
MAPK1 upregulated milk protein (show CSN2 ELISA Kits) synthesis through the Stat5 (show STAT5A ELISA Kits) and mTOR (show FRAP1 ELISA Kits) pathways.
Chronic hypoxia induces Egr-1 (show EGR1 ELISA Kits) via activation of ERK1/2 (show MAPK1/3 ELISA Kits) and contributes to pulmonary vascular remodeling.
ER Ca(2 (show CA2 ELISA Kits)+) release enhances eNOS (show NOS3 ELISA Kits) Ser (show SIGLEC1 ELISA Kits)-635 phosphorylation and function via ERK1/2 (show MAPK1/3 ELISA Kits) activation.
Cyclin-dependent kinase (show CDK1 ELISA Kits) inhibition did not affect the expression (mRNA and protein levels) and localization of maturation promoting factor(MPF (show MSLN ELISA Kits)) and MAPK, and had nearly no effect on kinase activities during maturation.
Thrombospondin 1 (show THBS1 ELISA Kits), fibronectin (show FN1 ELISA Kits), and vitronectin (show VTN ELISA Kits) are differentially dependent upon RAS, ERK1/2 (show MAPK1/3 ELISA Kits), and p38 (show MAPK14 ELISA Kits) for induction of vascular smooth muscle cell chemotaxis.
results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation
These data suggest that Gab1-ERK1/2 (show MAPK1/3 ELISA Kits) binding and their nuclear translocation play a crucial role in Egr-1 (show EGR1 ELISA Kits) nuclear accumulation.
Role of CaMKII (show CAMK2G ELISA Kits) in hydrogen peroxide activation of p38 MAPK (show MAPK14 ELISA Kits)/heat shock protein 27 (show HSP27 ELISA Kits) pathway and ERK1/2 (show MAPK1/3 ELISA Kits)
data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 ELISA Kits), mTOR (show FRAP1 ELISA Kits), p70S6K (show RPS6KB1 ELISA Kits), and ERK1/2 (show MAPK1/3 ELISA Kits).
Excess PLAC8 promotes an unconventional ERK2-dependent EMT (show ITK ELISA Kits) in colon cancer.
ERK1/2 (show MAPK1/3 ELISA Kits)-Akt1 (show AKT1 ELISA Kits) crosstalk regulates arteriogenesis in mice and zebrafish.
eena (show SH3GL1 ELISA Kits) plays an important role in the development of the myeloid cell through activation of the ERK1 (show MAPK3 ELISA Kits)/ERK2 pathway
ERK1 (show MAPK3 ELISA Kits) and ERK2 target common and distinct gene sets, confirming diverse roles for these kinases during embryogenesis; for ERK2 genes involved in cell-migration, mesendoderm differentiation and patterning were identified.
These results demonstrate that induction of Hsp70 (show HSPA1A ELISA Kits) in response to heat stress is dependent on ERK activation in Pac2 (show PSMG2 ELISA Kits) cells.
Data define distinct roles for ERK1 (show MAPK3 ELISA Kits) and ERK2 in developmental cell migration processes during zebrafish embryogenesis.
GLUL (show GLUL ELISA Kits) knockdown markedly inhibited the p38 MAPK (show MAPK14 ELISA Kits) and ERK1 (show MAPK3 ELISA Kits)/ERK2 signaling pathways in cultured breast cancer cells and reduces their proliferation.
These results suggested that HOXB7 (show HOXB7 ELISA Kits) stimulates ERK1/2 (show MAPK1/3 ELISA Kits) phosphorylation and provided evidence that HOXB7 (show HOXB7 ELISA Kits), besides its role in transcriptional regulation, also promotes cell motility and invasiveness.
High ERK2 expression is associated with castration-resistant prostate cancer.
combined use of butyrate and highly specific Syk (show SYK ELISA Kits) inhibitor BAY61-3606 does not enhance differentiation and apoptosis of colonocytes. Instead, BAY completely abolishes butyrate-induced differentiation and apoptosis in a Syk (show SYK ELISA Kits)- and ERK1/2 (show MAPK1/3 ELISA Kits)-dependent manner.
new findings indicating that canonical FGFR (show FGFR2 ELISA Kits)-ERK1/2 (show MAPK1/3 ELISA Kits) signaling entrapped hBMSCs in a pre-committed state and arrested further maturation of committed precursors.
mutually exclusive transcriptional regulation by AP-1 (cjun (show JUN ELISA Kits)/cfos) and non-canonical NF-kappaB (show NFKB1 ELISA Kits) (RelB (show RELB ELISA Kits)/p52 (show FKBP4 ELISA Kits)) downstream of MEK (show MAP2K1 ELISA Kits)-ERK (show EPHB2 ELISA Kits) and NIK (show MAP3K14 ELISA Kits)-IKK-alpha (show CHUK ELISA Kits)-NF-kappaB2 (p100 (show CUX1 ELISA Kits)) phosphorylation, respectively was responsible for persistent Ccl20 (show CCL20 ELISA Kits) expression in the colonic cells.
we have demonstrated a pathogenic role for aPL (show FASL ELISA Kits) containing samples, mediated via aPL (show FASL ELISA Kits)-b2GPI (show APOH ELISA Kits) interactions, resulting in activation of the pro-apoptotic p38 MAPK (show MAPK14 ELISA Kits) pathway.
LPS (show IRF6 ELISA Kits)-activated ERK1,2 was at least partly involved in the observed effects on periodontal ligament stem cell differentiation capacity, acquisition of myofibroblastic attributes, and changes of their immunomodulatory features.
The findings indicate that ERK (show EPHB2 ELISA Kits) and JNK (show MAPK8 ELISA Kits) signaling pathways, as well as NF-kappaB (show NFKB1 ELISA Kits)-mediated signaling are important contributors to the pathogenesis of Kashin-Beck disease.
observations provide important insights into the regulation of EpCAM (show EPCAM ELISA Kits) expression during EMT (show ITK ELISA Kits), demonstrate an unexpected role for EpCAM (show EPCAM ELISA Kits) in the regulation of ERK (show EPHB2 ELISA Kits) and define a novel double-negative feedback loop between EpCAM (show EPCAM ELISA Kits) and ERK (show EPHB2 ELISA Kits) that contributes to the regulation of EMT (show ITK ELISA Kits).
Cortical neuron-specific deletion of extracellular signal-regulated kinases Erk1 (show MAPK3 ELISA Kits) or Erk2 significantly increased the duration of wakefulness.
pERK1/2 is a regulator of CD44 (show CD44 ELISA Kits) expression, and increased CD44 (show CD44 ELISA Kits) expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
mmLDL increased the serum concentrations and expression of ICAM-1 (show ICAM1 ELISA Kits) and VCAM-1 (show VCAM1 ELISA Kits) by activating the ERK1/2 (show MAPK1/3 ELISA Kits) pathway, resulting in the expression of ETB (show EDNRB ELISA Kits) receptors and the enhancement of contractile function in vascular smooth muscle.
These results indicate a crucial role of the Rapgef2 (show RAPGEF2 ELISA Kits)-Rap1A (show RAP1A ELISA Kits)-ERK (show EPHB2 ELISA Kits)-c-jun (show JUN ELISA Kits) pathway in regulation of the AJ formation in RGCs.
MFA has a protective effect on alcohol-induced liver injury, which may be related to its antioxidant,anti-inflammatory,lipid-eliminating properties and its ability to regulate the NOX4 (show NOX4 ELISA Kits)/ROS (show ROS1 ELISA Kits)-MAPK signalling pathway.
MAPK3 (show MAPK3 ELISA Kits)/1 participates in primordial follicle activation through mTORC1-KITL (show KITLG ELISA Kits) signaling.
The purpose of this study was to investigate mechanisms that govern the regulation of Npnt (show NPNT ELISA Kits) gene expression by IL-1beta (show IL1B ELISA Kits) in osteoblasts.
The results of this study suggested that Erk2 activation in astrocytes plays a crucial role in aggravating demyelinating inflammation by inducing inflammatory mediators and gliosis.
At low oxLDL levels LOX-1 (show OLR1 ELISA Kits) activates the protective Oct-1 (show POU2F1 ELISA Kits)/SIRT1 (show SIRT1 ELISA Kits) pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 (show MAPK1/3 ELISA Kits) pathway.
Studies indicate that progesterone receptor (show PGR ELISA Kits) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (show CXCL9 ELISA Kits)-6over) phosphatase and tensin homolog protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (show MAPK1/3 ELISA Kits) and its target genes.
Early activation of MAPK p44/42 is involved in deoxynivalenol -induced disruption of intestinal barrier function and tight junction network signaling.
Agonist stimulation of vascular smooth muscle increases PKC (show FYN ELISA Kits) activity, which, in turn, increases MKP-1 (show DUSP1 ELISA Kits) activity and maintains MAPK1 activity at submaximal values.
sub-vasomotor concentration of ET-1 (show EDN1 ELISA Kits) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (show MAPK14 ELISA Kits) kinase-mediated production of superoxide from NADPH oxidase (show NOX1 ELISA Kits) following ETA receptor activation
Treatment with ERK inhibitors or ERK1/2 (show MAPK1/3 ELISA Kits) knockdown significantly suppressed porcine epidemic diarrhea virus progeny production.
This study reveals a new function of the gE glycoprotein of pseudorabies virus and suggests that pseudorabies virus, through activation of ERK1/2 (show MAPK1/3 ELISA Kits) signaling, has a substantial impact on T cell behavior.
CSF2 (show CSF2 ELISA Kits) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 (show MAPK1/3 ELISA Kits) MAPK-dependent MTOR (show FRAP1 ELISA Kits) signal transduction cascades.
PGRN (show GRN ELISA Kits) inhibits adipogenesis in porcine preadipocytes partially through ERK activation mediated PPARgamma (show PPARG ELISA Kits) phosphorylation.
Data show that proinflammatory cytokines induction was ERK1/2 (show MAPK1/3 ELISA Kits) and JNK1 (show MAPK8 ELISA Kits)/2 dependent.
The authors show that porcine circovirus type 2 (PCV2) activates ERK1/2 (show MAPK1/3 ELISA Kits) in PCV2-infected PK15 cells dependent on viral replication.
20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.
Here the authors show that CPEB4 activity is regulated by ERK2- and Cdk1-mediated hyperphosphorylation. These phosphorylation events additively activate CPEB4 in M-phase by maintaining it in its monomeric state.
The reciprocal feedback observed between MPF (show MSLN ELISA Kits) and ERK2 in meiosis is not observed during mitotic M-phase in cell-free Xenopus embryo extracts.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
mitogen-activated protein kinase 1
, MAP kinase 1
, MAP kinase 2
, MAPK 1
, MAPK 2
, extracellular signal-regulated kinase 2
, mitogen-activated protein kinase 2
, MAP kinase isoform p42
, protein tyrosine kinase ERK2
, mitogen activated protein kinase 1
, extracellular-signal-regulated kinase 2
, extracellular signal-regulated kinase-2
, MAP kinase
, mitogen-activated protein kinase 1b
, myelin basic protein kinase-like protein
, mitogen-activated protein kinase 1a