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Browse our MAPK12 Proteins (MAPK12)

Full name:
Mitogen-Activated Protein Kinase 12 Proteins (MAPK12)
On www.antibodies-online.com are 14 Mitogen-Activated Protein Kinase 12 (MAPK12) Proteins from 7 different suppliers available. Additionally we are shipping MAPK12 Antibodies (103) and MAPK12 Kits (4) and many more products for this protein. A total of 135 MAPK12 products are currently listed.
Synonyms:
ATMPK12, AW123708, ERK3, Erk6, etID309866.18, mapk12, MGC160082, mitogen-activated protein kinase 12, P38gamma, Prkm12, SAPK-3, Sapk3, si:dkey-14d8.5, T3F17.28, wu:fa05c12, zgc:101695
list all proteins Gene Name GeneID UniProt
MAPK12 6300 P53778
MAPK12 29857 O08911
MAPK12 60352 Q63538

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MAPK12 Proteins (MAPK12) by Origin

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Top referenced MAPK12 Proteins

  1. Human MAPK12 Protein expressed in Escherichia coli (E. coli) - ABIN667620 : Court, dos Remedios, Cordell, Bogoyevitch: Cardiac expression and subcellular localization of the p38 mitogen-activated protein kinase member, stress-activated protein kinase-3 (SAPK3). in Journal of molecular and cellular cardiology 2002 (PubMed)
    Show all 2 references for ABIN667620

  2. Human MAPK12 Protein expressed in Baculovirus infected Insect Cells - ABIN2006608 : Stiffler, Grantcharova, Sevecka, MacBeath: Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays. in Journal of the American Chemical Society 2006 (PubMed)
    Show all 2 references for ABIN2006608

More Proteins for MAPK12 Interaction Partners

Arabidopsis thaliana Mitogen-Activated Protein Kinase 12 (MAPK12) interaction partners

  1. MPK9 (show MAPK9 Proteins) and MPK12 are key regulators mediating both abscisic acid (ABA) and Methyl jasmonate (MeJA) signalling in guard cells.

  2. MPK9 (show MAPK9 Proteins) and MPK12 function redundantly downstream of extracellular reactive oxygen production and intracellular accumulation, cytosolic alkalisation and Ca(2 (show CA2 Proteins)+)cytosolic oscillation in yeast elcictor-induced stomatal closure

  3. MPK9 (show MAPK9 Proteins) and MPK12 act downstream of ROS (show ROS1 Proteins) and cytosolic Ca2 (show CA2 Proteins)+ and upstream of anion channels in the guard cell abscisic acid signaling cascade.

  4. MAP kinases MPK9 (show MAPK9 Proteins) and MPK12 are preferentially expressed in guard cells and positively regulate ROS (show ROS1 Proteins)-mediated ABA signaling.

  5. MPK12 is both a physiological substrate of IBR5 and a novel negative regulator of auxin signaling.

Human Mitogen-Activated Protein Kinase 12 (MAPK12) interaction partners

  1. during interphase ERK3 (show MAPK4 Proteins) is mainly resident in the nucleoplasm in association with ribonuclear proteins involved in early pre-mRNA splicing, it undergoes cell cycle-dependent redistribution and, during apoptosis

  2. Taken together our data suggest that as cells initiate adhesion to matrix increasing levels of ERK3 (show MAPK4 Proteins) at the cell periphery are required to orchestrate cell morphology changes which can then drive migratory behavior.

  3. p38gamma and p38delta reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD therapy

  4. analysis of how allosteric regulation of p38gamma and PTPN3 involves a PDZ domain-modulated complex formation

  5. Thus, in endothelial cells p38alpha (show MAPK14 Proteins) mediates apoptotic signaling, whereas p38beta (show MAPK11 Proteins) and p38gamma transduce survival signaling

  6. p38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response.

  7. SEPW1 (show SEPW1 Proteins) silencing increases MKK4 (show MAP2K4 Proteins), which activates p38gamma, p38delta, and JNK2 (show MAPK9 Proteins) to phosphorylate p53 (show TP53 Proteins) on Ser (show SIGLEC1 Proteins)-33 and cause a transient G(1) arrest.

  8. phosphorylation at Ser (show SIGLEC1 Proteins)-118 is required for ER to bind both p38gamma and c-Jun (show JUN Proteins), thereby promoting ER relocation from ERE to AP-1 (show FOSB Proteins) promoter sites.

  9. p38gamma mitogen-activated protein kinase (show MAPK1 Proteins) regulates breast cancer cell motility and metastasis, in part, by controlling expression of the metastasis-associated small GTPase (show RACGAP1 Proteins) RhoC (show RHOC Proteins).

  10. a new paradigm in which p38gamma actively regulates the drug-Topo IIalpha signal transduction, and this may be exploited to increase the therapeutic activity of Topo II (show TOP2 Proteins) drugs.

Mouse (Murine) Mitogen-Activated Protein Kinase 12 (MAPK12) interaction partners

  1. p38gamma mitogen-activated protein kinase (show MAPK1 Proteins) mediates inflammatory signaling to promote colon tumorigenesis

  2. p38gamma and p38delta reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD therapy

  3. p38gamma and p38delta control heart growth by modulating mTOR (show FRAP1 Proteins) pathway through DEPTOR (show DEPTOR Proteins) phosphorylation and subsequent degradation.

  4. Findings provide genetic evidence that p38gamma and p38delta have essential roles in skin tumour development.

  5. Together, our results establish that p38gamma and p38delta are central to colitis-associated colon cancer formation through regulation of hematopoietic cell response to injury, and validate p38gamma and p38kappa as potential targets for cancer therapy.

  6. An energetic signal may trigger phosphorylation of the p38-gamma isoform which may explain how contractions differentially activate signaling pathways.

  7. p38gamma and p38delta are crucial regulators of inflammatory joint destruction in collagen-induced arthritis.

  8. p38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response.

  9. p38gamma and p38delta kinases regulate the Toll-like receptor 4 (TLR4 (show TLR4 Proteins))-induced cytokine production by controlling ERK1/2 protein kinase (show CDK7 Proteins) pathway activation

  10. results indicate that p38gamma and p38delta have a role in the suppression of tumor development

MAPK12 Protein Profile

Protein Summary

Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.

Alternative names and synonyms associated with MAPK12

  • mitogen-activated protein kinase 12 (MPK12)
  • mitogen-activated protein kinase 12 (MAPK12)
  • mitogen-activated protein kinase 12b (mapk12b)
  • mitogen-activated protein kinase 12a (mapk12a)
  • mitogen-activated protein kinase 12 (Mapk12)
  • ATMPK12 protein
  • AW123708 protein
  • ERK3 protein
  • Erk6 protein
  • etID309866.18 protein
  • mapk12 protein
  • MGC160082 protein
  • mitogen-activated protein kinase 12 protein
  • P38gamma protein
  • Prkm12 protein
  • SAPK-3 protein
  • Sapk3 protein
  • si:dkey-14d8.5 protein
  • T3F17.28 protein
  • wu:fa05c12 protein
  • zgc:101695 protein

Protein level used designations for MAPK12

mitogen-activated protein kinase 12 , MAP kinase 12 , MAPK 12 , extracellular signal-regulated kinase 6 , fa05c12 , p38-gamma , stress-activated protein kinase 3 , ERK-6 , MAP kinase p38 gamma , mitogen-activated protein kinase 3 , mitogen-activated protein kinase p38 gamma , mitogen activated protein kinase 12 , stress activated protein kinase 3 , SAP kinase-3

GENE ID SPECIES
819215 Arabidopsis thaliana
512943 Bos taurus
557810 Danio rerio
30681 Danio rerio
769763 Gallus gallus
6300 Homo sapiens
715745 Macaca mulatta
29857 Mus musculus
60352 Rattus norvegicus
574062 Sus scrofa
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