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anti-Human MKNK1 antibody for Enzyme Immunoassay

Recommended MKNK1 Antibody (supplied by: Log in to see )

Antigen
MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Antibodies
  • 2410048M24Rik
  • Erk-1
  • ERK1
  • Erk1
  • Ert2
  • ERT2
  • Esrk1
  • MAPK1
  • MKNK1
  • Mnk1
  • MNK1
  • Mtap2k
  • p44
  • p44erk1
  • p44mapk
  • Prkm3
  • zgc:171912
Epitope
N-Term
22
16
13
8
8
7
6
5
5
5
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
134
52
38
3
1
Host
Rabbit
94
41
Clonality
Polyclonal
Conjugate
This MKNK1 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
123
103
31
25
18
2
1
1
1
Supplier
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Catalog No. ABIN359308
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008870071 ABIN781895 EIA IF IHC (p) WB Mouse IgG2a Log in to see 2F12
0.0008870071 ABIN781890 EIA IF IHC (p) WB Mouse IgG1 Log in to see 2H8

Top referenced anti-MKNK1 antibody for Enzyme Immunoassay

Similar anti-MKNK1 Antibodies

Application / Reactivity Human
ELISA 102 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 25 Antibodies
Immunohistochemistry (IHC) 32 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 19 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 124 Antibodies

General

Antigen MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Antibodies
Epitope N-Term
(22), (16), (13), (8), (8), (7), (6), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(134), (52), (38), (3), (1)
Host Rabbit
(94), (41)
Clonality
Polyclonal
Conjugate This MKNK1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(123), (103), (31), (25), (18), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-MKNK1 Antibody

Target Details MKNK1 Application Details Handling References for anti-MKNK1 Antibody (ABIN359308) Images
Specificity This antibody reacts to MKNK1.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MKNK1.
Isotype Ig

Target Details MKNK1

Product Details anti-MKNK1 Antibody Application Details Handling References for anti-MKNK1 Antibody (ABIN359308) Images back to top
Antigen
Alternative Name MKNK1 (MKNK1 Antibody Abstract)
Background MKNK1 encodes a predicted 424-amino acid protein containing a sequence typical of the catalytic domain of serine/threonine kinases and a putative N-terminal nuclear localization signal sequence.C-terminal region of MKNK1 was phosphorylated and activated in vivo and in vitro by ERK1 and p38 MAP kinases, but not by JNK/SAPK. The activated ERK is essential for the activation of MKNK1 in insect cells. MKNK1 was activated following stimulation of HeLa cells with a variety of extracellular stimuli. MNK1 bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2, and also binds strongly to the stress-activated kinase, p38.Synonyms: MAP kinase-interacting serine/threonine-protein kinase 1, MNK1
Gene ID 8569, 9606
UniProt Q9BUB5
Pathways MAPK Signaling

Application Details

Product Details anti-MKNK1 Antibody Target Details MKNK1 Handling References for anti-MKNK1 Antibody (ABIN359308) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MKNK1 Antibody Target Details MKNK1 Application Details References for anti-MKNK1 Antibody (ABIN359308) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-MKNK1 Antibody (ABIN359308)

Product Details anti-MKNK1 Antibody Target Details MKNK1 Application Details Handling Images back to top
Background publications

Orton, Ling, Waskiewicz, Cooper, Merrick, Korneeva, Rhoads, Sonenberg, Traugh: "Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38649-57, 2004

Images

Product Details anti-MKNK1 Antibody Target Details MKNK1 Application Details Handling References for anti-MKNK1 Antibody (ABIN359308) back to top
Supplier Images
Western Blotting (WB) image for anti-MKNK1 antibody (MAP Kinase Interacting serine/threonine Kinase 1) (N-Term) (ABIN359308) The anti-MKNK1 Pab is used in Western blot to detect MKNK1 in A2058 tissue lysate