|Application / Reactivity||Mouse (Murine)||Human||Rat (Meriones)|
|Western Blotting (WB)||45 Antibodies||122 Antibodies||1 Antibodies|
|Proximity Ligation Assay (PLA)||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||18 Antibodies||6 Antibodies|
|Immunohistochemistry (IHC)||31 Antibodies||16 Antibodies|
|Immunofluorescence (IF)||25 Antibodies||3 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies||1 Antibodies|
|Enzyme Immunoassay (EIA)||3 Antibodies||1 Antibodies|
|ELISA (Capture)||1 Antibodies|
|ELISA||42 Antibodies||101 Antibodies|
|Antigen||MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Meriones) Alternatives|
|Conjugate||This MKNK1 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-MKNK1 AntibodyTarget Details MKNK1 Application Details Handling References for anti-MKNK1 Antibody (ABIN2801944) Images
Target Details MKNK1Product Details anti-MKNK1 Antibody Application Details Handling References for anti-MKNK1 Antibody (ABIN2801944) Images back to top
|Alternative Name||Mnk1 (MKNK1 Antibody Abstract)|
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.
Synonyms: MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, MKNK1, MNK1
|Molecular Weight||51342 Da|
Application DetailsProduct Details anti-MKNK1 Antibody Target Details MKNK1 Handling References for anti-MKNK1 Antibody (ABIN2801944) Images back to top
|Application Notes||WB - 1:250-1:1000|
|Restrictions||For Research Use only|
HandlingProduct Details anti-MKNK1 Antibody Target Details MKNK1 Application Details References for anti-MKNK1 Antibody (ABIN2801944) Images back to top
|Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.|
|Precaution of Use||WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.|
References for anti-MKNK1 Antibody (ABIN2801944)Product Details anti-MKNK1 Antibody Target Details MKNK1 Application Details Handling Images back to top
|Product cited in:||
OLoghlen, González, Piñeiro et al.: "Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1." in: Experimental cell research, Vol. 299, Issue 2, pp. 343-55, 2004 (PubMed).
Knauf, Tschopp, Gram: "Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2." in: Molecular and cellular biology, Vol. 21, Issue 16, pp. 5500-11, 2001 (PubMed).
Fukunaga, Hunter: "MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates." in: The EMBO journal, Vol. 16, Issue 8, pp. 1921-33, 1997 (PubMed).
Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1. ..." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).
ImagesProduct Details anti-MKNK1 Antibody Target Details MKNK1 Application Details Handling References for anti-MKNK1 Antibody (ABIN2801944) back to top