Browse our Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit Proteins (HADHB)

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Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit Proteins (HADHB)
On www.antibodies-online.com are 13 Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) Proteins from 5 different suppliers available. Additionally we are shipping Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit Antibodies (74) and Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit Kits (9) and many more products for this protein. A total of 103 Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit products are currently listed.
Synonyms:
4930479F15Rik, ECHB, fb14g10, Hadhb, Mtpb, thiolase, TP-BETA, wu:fb14g10, zgc:56274
list all proteins Gene Name GeneID UniProt
HADHB 3032 P55084
Rat HADHB HADHB 171155 Q60587
HADHB 231086 Q99JY0

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Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit Proteins (HADHB) by Origin

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More Proteins for Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit Interaction Partners

Human Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) interaction partners

  1. Exposure to bezafibrate (400 muM for 48 h) increased the abundance of HADHA (show HADHA Proteins) and HADHB mRNAs.

  2. nonstructural protein 5 (show CAPS Proteins) (NS5 (show RAF1 Proteins)) interacted with hydroxyacyl-CoA dehydrogenase (show HADH Proteins) alpha and beta subunits, two components of the mitochondrial trifunctional protein (MTP (show MT1B Proteins)) involved in LCFA beta-oxidation

  3. Mutations in HADHB, which encodes the beta-subunit of mitochondrial trifunctional protein, cause infantile onset hypoparathyroidism and peripheral polyneuropathy.

  4. Heterozygous mutation in HADHB gene cause early-onset axonal axonal Charcot-Marie-tooth disease.

  5. The results demonstrated that ERbeta (show ESR2 Proteins) was indeed associated and colocalized with HADHB within mitochondria.

  6. HADHB is a functional molecular target of estrogen receptor alpha (show ESR1 Proteins) in the mitochondria, and the interaction may play an important role in the estrogen-mediated lipid metabolism in animals and humans.

  7. mutational analysis of the HADHB gene, which encodes long-chain 3-ketoacyl-CoA thiolase, identified compound heterozygous mutations of c.520C>T (p.R141C) and c.1331G>A (p.R411K) in a case of mitochondrial trifunctional protein deficiency

  8. Results emphasize the value of cDNA analysis in the characterization of HADHA (show HADHA Proteins) and HADHB mutations and further strengthen the model of haploinsufficiency as a major pathomechanism in MTP (show MT1B Proteins) defects.

  9. Recombinant mitochondrial trifunctional protein displayed 2-enoyl-CoA hydratase, l-3-hydroxyacyl-CoA dehydrogenase, and 3-ketoacyl-CoA thiolase activities.

  10. The present findings showed that all missense mutations in HADHB were disease-causing.

Cow (Bovine) Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) interaction partners

  1. Mutation analysis of the HADHB gene of patient 4 identified compound heterozygosity of N114D/N307D.

Mouse (Murine) Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) interaction partners

  1. nonstructural protein 5 (show CAPS Proteins) (NS5 (show RAF1 Proteins)) interacted with hydroxyacyl-CoA dehydrogenase (show HADH Proteins) alpha and beta subunits, two components of the mitochondrial trifunctional protein (MTP (show LAPTM4A Proteins)) involved in LCFA beta-oxidation

Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) Protein Profile

Protein Summary

This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found\; however, their full-length nature is not known.

Alternative names and synonyms associated with Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB)

  • hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB)
  • hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (hadhb)
  • hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (Hadhb)
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (hadhb)
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (Hadhb)
  • long-chain 3-ketoacyl-CoA thiolase (LCTHIO)
  • 4930479F15Rik protein
  • ECHB protein
  • fb14g10 protein
  • Hadhb protein
  • Mtpb protein
  • thiolase protein
  • TP-BETA protein
  • wu:fb14g10 protein
  • zgc:56274 protein

Protein level used designations for HADHB

2-enoyl-Coenzyme A (CoA) hydratase, beta subunit , 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit , acetyl-CoA acyltransferase , beta-ketothiolase , hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit , trifunctional enzyme subunit beta, mitochondrial , hydroxyacyl dehydrogenase, subunit B , TP-beta , dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit , mitochondrial trifunctional protein, beta subunit , 3-ketoacyl-Coenzyme A thiolase , TP-Beta , enoyl-Coenzyme A hydratase, beta subunit , trifunctional enzyme beta subunit, mitochondrial , dehydrogenase/3-ketoacyl-Coenzyme A thiolase , hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit

GENE ID SPECIES
3032 Homo sapiens
379769 Xenopus laevis
421995 Gallus gallus
281811 Bos taurus
171155 Rattus norvegicus
607926 Canis lupus familiaris
459080 Pan troglodytes
336606 Danio rerio
231086 Mus musculus
397017 Sus scrofa
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