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Browse our Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) ELISA Kits

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Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) ELISA Kits (SMPD2)
On www.antibodies-online.com are 9 Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) ELISA Kits from 4 different suppliers available. Additionally we are shipping Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Antibodies (46) and Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Proteins (5) and many more products for this protein. A total of 63 Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) products are currently listed.
Synonyms:
AW108287, ISC1, NSMASE, NSMASE1, SMPD2
list all ELISA KIts Gene Name GeneID UniProt
SMPD2 20598 O70572
SMPD2 83537 Q9ET64
SMPD2 6610 O60906

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Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) ELISA Kits by Reactivity

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More ELISA Kits for Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Interaction Partners

Zebrafish Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) interaction partners

Mouse (Murine) Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) interaction partners

  1. cells deficient in acid ceramidase (aCDase (show ASAH1 ELISA Kits)) also exhibited defects in CCL5 (show CCL5 ELISA Kits) induction, whereas cells deficient in sphingosine kinase-1 (show SPHK1 ELISA Kits) and -2 exhibited higher levels of CCL5 (show CCL5 ELISA Kits).

  2. nSMase2 has a role in ceramide generation, aberrant apoptosis, and lung injury under cigarette smoke exposure

  3. Neutral sphingomyelinase 1 deficiency in the mouse causes no lipid storage disease. (nSMase 1)

  4. NSMase-2 could be involved in IL-1beta (show IL1B ELISA Kits)-induced JNK (show MAPK8 ELISA Kits) activation in hepatocytes

  5. Nuclear sphingomyelin-synthase and protein kinase C delta (show PKCd ELISA Kits) are expressed in melanoma cells

  6. Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase (show ASAH1 ELISA Kits) have roles in cutaneous aging

  7. Peptidoglycan activates the nSMase/ceramide pathway to induce MKK3 (show MAP2K3 ELISA Kits)/6/p38 MAPK (show MAPK14 ELISA Kits) activation, which in turn initiates NF-kappaB (show NFKB1 ELISA Kits) activation and ultimately induces COX-2 (show COX2 ELISA Kits) expression in macrophages.

Human Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) interaction partners

  1. Interestingly, neutral but not acid sphingomyelinase (show SMPD1 ELISA Kits) was mandatory for PorBIA -mediated Neisseria gonorrhoeae invasion into host cells.

  2. nSMase1 (sphingomyelin phosphodiesterase 2, SMPD2)has a common central role in ceramide signaling during the stress and cytokine responses and apoptosis.

  3. These data suggest that Ox-LDL activates N-SMase-ceramide signaling pathway, and stimulates phosphorylation of p38 MAPK (show MAPK14 ELISA Kits), leading to apoptosis in vascular smooth muscle cells, which initiates VSMC calcification.

  4. cells deficient in acid ceramidase (aCDase (show ASAH1 ELISA Kits)) also exhibited defects in CCL5 (show CCL5 ELISA Kits) induction, whereas cells deficient in sphingosine kinase-1 (show SPHK1 ELISA Kits) and -2 exhibited higher levels of CCL5 (show CCL5 ELISA Kits).

  5. nSMase2 has a role in ceramide generation, aberrant apoptosis, and lung injury under cigarette smoke exposure

  6. N-SMase at the cytofacial plasma membrane is an essential element for the proper orientation of PMNs in FMLP (show FPR1 ELISA Kits) gradients, at least in part by polarizing the distribution of Rac 1/2 and RhoA (show RHOA ELISA Kits) GTPases.

  7. Results demonstrate that WithaD enhance the ceramide accumulation by activating N-SMase 2, modulate phosphorylation of the JNK (show MAPK8 ELISA Kits) and p38MAPK (show MAPK14 ELISA Kits) and induced apoptosis in both myeloid and lymphoid cells along with primary cells derived from leukemia patients.

  8. Data show DA remarkably increased the NSMase2 message and protein, whereas little change in NSMase1 and NSMase3 (show SMPD4 ELISA Kits) mRNAs.

  9. nSMase2 functions as a growth suppressor in MCF7 cells, linking confluence to the G(0)/G(1) cell cycle check point.

  10. identification of 15 polymorphisms, including 9 novel SNPs, in the SMPD2 gene; one haplotype showed associations with the extrinsic type of atopic dermatitis subgroup

Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) Antigen Profile

Antigen Summary

This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase.

Alternative names and synonyms associated with Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2)

  • sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (SMPD2) Elisa Kit
  • sphingomyelin phosphodiesterase 2, neutral (smpd2) Elisa Kit
  • sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (smpd2) Elisa Kit
  • sphingomyelin phosphodiesterase 2, neutral (Smpd2) Elisa Kit
  • sphingomyelin phosphodiesterase 2, neutral membrane (Smpd2) Elisa Kit
  • AW108287 Elisa Kit
  • ISC1 Elisa Kit
  • NSMASE Elisa Kit
  • NSMASE1 Elisa Kit
  • SMPD2 Elisa Kit

Protein level used designations for SMPD2

sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) , Mg2+-dependent neutral sphingomyelinase , neutral SMase I , neutral sphingomyelinase , sphingomyelin phosphodiesterase 2 , sphingomyelin phosphodiesterase 2-like , N-SMase , lyso-PAF-PLC , lyso-platelet-activating factor-phospholipase C , neutral sphingomyelinase 1

GENE ID SPECIES
462928 Pan troglodytes
567548 Danio rerio
698865 Macaca mulatta
770663 Gallus gallus
100145256 Xenopus (Silurana) tropicalis
100394711 Callithrix jacchus
100455395 Pongo abelii
100479011 Ailuropoda melanoleuca
100512027 Sus scrofa
100604925 Nomascus leucogenys
20598 Mus musculus
83537 Rattus norvegicus
6610 Homo sapiens
481957 Canis lupus familiaris
509018 Bos taurus
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