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|Antigen||Epidermal Growth Factor Receptor (EGFR) Antibodies|
|Conjugate||This EGFR antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Simple Western (SimWes), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-EGFR AntibodyTarget Details EGFR Application Details Handling References for anti-EGFR antibody (ABIN4900628) Images
|Specificity||Detects human EGFR when phosphorylated at Y1173 in Western blots.|
|Sterility||0.2 μm filtered|
|Immunogen||Phosphopeptide containing human EGFR Y1173 site|
Target Details EGFRProduct Details anti-EGFR Antibody Application Details Handling References for anti-EGFR antibody (ABIN4900628) Images back to top
|Alternative Name||EGF R/ErbB1 (EGFR Antibody Abstract)|
|Background||Alternative Names: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 22.214.171.124, EGF R, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ErbB, ErbB1, ERBB1PIG61, HER1, HER-1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1|
|Research Area||Receptors, Growth Factors, Hormones, Cancer, Tyrosine Kinases|
|Pathways||NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation|
Application DetailsProduct Details anti-EGFR Antibody Target Details EGFR Handling References for anti-EGFR antibody (ABIN4900628) Images back to top
Western Blot 0.2 μg/mL
Simple Western 2 μg/mL
Immunohistochemistry 5-15 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 5-15 μg/mL
|Restrictions||For Research Use only|
HandlingProduct Details anti-EGFR Antibody Target Details EGFR Application Details References for anti-EGFR antibody (ABIN4900628) Images back to top
|Reconstitution||Reconstitute at 0.2 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-EGFR antibody (ABIN4900628)Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling Images back to top
|Product cited in:||
Kefaloyianni, Muthu, Kaeppler, Sun, Sabbisetti, Chalaris, Rose-John, Wong, Sagi, Waikar, Rennke, Humphreys, Bonventre, Herrlich: "ADAM17 substrate release in proximal tubule drives kidney fibrosis." in: JCI insight, Vol. 1, Issue 13, 2016 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Mouse (Murine)).
Weissenbacher, Vrekoussis, Roeder, Makrigiannakis, Mayr, Ditsch, Friese, Jeschke, Dian: "Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors: Correlation to Mucin-1 and Galectin-3 Expression." in: International journal of molecular sciences, Vol. 14, Issue 3, pp. 4783-92, 2013 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).
Xue, Campbell, Jackson: "Protein C is an autocrine growth factor for human skin keratinocytes." in: The Journal of biological chemistry, Vol. 282, Issue 18, pp. 13610-6, 2007 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).
Kaneko, Kubo, Hata, Yamaguchi, Yamashita: "Repulsion of cerebellar granule neurons by chondroitin sulfate proteoglycans is mediated by MAPK pathway." in: Neuroscience letters, Vol. 423, Issue 1, pp. 62-7, 2007 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
ImagesProduct Details anti-EGFR Antibody Target Details EGFR Application Details Handling References for anti-EGFR antibody (ABIN4900628) back to top