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anti-Rat (Rattus) EGFR antibody for Enzyme Immunoassay

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • 9030024J15Rik
  • AI552599
  • C-erb
  • c-erbB
  • CG10079
  • D-Egf
  • d-egf-r
  • D-EGFR
  • Degfr
  • dEgfr
  • DEgfr
  • DEGFR
  • dEGFR
  • dEGFR1
  • der
  • DER
  • Der
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DER flb
  • Dmel\\CG10079
  • DmHD-33
  • EFG-R
  • Egf
  • EGF-R
  • Egf-r
  • EgfR
  • EGfr
  • EGFr
  • EGFR
  • egfr
  • egfr1
  • EGFR12
  • EGFR15
  • EK2-6
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • ERBB
  • Erbb
  • ErbB-1
  • ERBB1
  • Erbb2
  • Errb1
  • Errp
  • flb
  • HD-33
  • HER1
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57Ea
  • l(2)57EFa
  • mENA
  • mor1
  • PIG61
  • TOP
  • top
  • top/DER
  • top/flb
  • Torpedo/DER
  • Torpedo/Egfr
  • torpedo/Egfr
  • torpedo/egfr
  • wa-2
  • wa2
  • Wa5
Epitope
AA 1189-1199, pTyr1197
146
138
57
56
53
51
49
48
46
45
44
44
35
33
32
30
30
25
24
23
23
23
23
22
22
18
18
17
16
14
14
13
13
13
13
13
13
13
13
11
10
10
10
9
9
9
8
8
8
8
8
8
7
7
6
6
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
2147
740
606
21
14
14
12
10
7
7
4
2
1
1
1
Host
Rabbit
1373
687
60
44
4
2
Clonality
Polyclonal
Conjugate
This EGFR antibody is un-conjugated
93
73
64
55
45
43
25
24
23
21
21
21
21
21
21
21
20
19
19
19
19
19
19
19
19
19
19
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1311
565
505
441
414
243
232
180
86
74
67
54
25
11
11
9
8
5
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN401341
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008854274 ABIN118051 EIA IHC (p) IP WB Rabbit AA 1168-1180 Log in to see Polyclonal 1
0.0008854274 ABIN401323 EIA WB Rabbit IgG AA 1189-1199 Log in to see Polyclonal 4
0.0008854274 ABIN126757 EIA IP WB Mouse IgG1 pThr678 Log in to see 3F2
0.0008854274 ABIN126770 EIA IP WB Mouse IgG1 pTyr1092 Log in to see 15A2
0.0008854274 ABIN318810 EIA WB Rabbit IgG AA 1189-1199 Log in to see Polyclonal 1
0.0008854274 ABIN126768 EIA IP WB Biotin Mouse IgG1 pTyr1092 Log in to see 15A2
0.0008854274 ABIN126756 EIA IP WB Biotin Mouse IgG1 pThr678 Log in to see 3F2
0.0008854274 ABIN265396 EIA IHC (p) WB Rabbit Log in to see Polyclonal
0.0008854274 ABIN372504 EIA IF IHC (p) IP WB Sheep IgG Log in to see Polyclonal

Top referenced anti-EGFR antibody for Enzyme Immunoassay

Similar anti-EGFR Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 123 Antibodies 136 Antibodies
Enzyme Immunoassay (EIA) 10 Antibodies 23 Antibodies
Flow Cytometry (FACS) 3 Antibodies 64 Antibodies
Immunochromatography (IC) 3 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 30 Antibodies 32 Antibodies
Immunofluorescence (IF) 55 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 188 Antibodies
Immunohistochemistry (IHC) 166 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 96 Antibodies
Immunoprecipitation (IP) 22 Antibodies
Intracellular Staining (ICS) 2 Antibodies
Western Blotting (WB) 395 Antibodies

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope AA 1189-1199, pTyr1197
(146), (138), (57), (56), (53), (51), (49), (48), (46), (45), (44), (44), (35), (33), (32), (30), (30), (25), (24), (23), (23), (23), (23), (22), (22), (18), (18), (17), (16), (14), (14), (13), (13), (13), (13), (13), (13), (13), (13), (11), (10), (10), (10), (9), (9), (9), (8), (8), (8), (8), (8), (8), (7), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(2147), (740), (606), (21), (14), (14), (12), (10), (7), (7), (4), (2), (1), (1), (1)
Host Rabbit
(1373), (687), (60), (44), (4), (2)
Clonality
Polyclonal
Conjugate This EGFR antibody is un-conjugated
(93), (73), (64), (55), (45), (43), (25), (24), (23), (21), (21), (21), (21), (21), (21), (21), (20), (19), (19), (19), (19), (19), (19), (19), (19), (19), (19), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(1311), (565), (505), (441), (414), (243), (232), (180), (86), (74), (67), (54), (25), (11), (11), (9), (8), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling References for anti-EGFR Antibody (ABIN401341) Images
Specificity This antibody is directed against the phosphorylated form of EGFR protein at the pY1197 residue.
Purification Affinity chromatography
Immunogen Synthetic peptide corresponding to amino acids 1189-1199 of human EGFR protein
Isotype IgG

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling References for anti-EGFR Antibody (ABIN401341) Images back to top
Antigen
Alternative Name EGFR / ERBB1 (EGFR Antibody Abstract)
Background EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. Growth factor receptors are involved not only in promoting the proliferation of normal cells but also in the aberrant growth of many types of human tumors. For example, the epidermal growth factor receptor (EGFR) is mutated and/or overexpressed in many common solid human squamous cell carcinomas including breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. Overexpression of the EGFR gene occurs in carcinomas with and without gene amplification. EGFR and erbB-2 are particularly important in breast cancer because increased production or activation has been associated with poor prognosis. EGFR belongs to a family of growth factor receptors, which also includes ErbB-2/HER-2/neu, ErbB-3/HER-3/neu and ErbB-4/HER-4neu. EGFR can heterodimerize with each of the members of this family.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
Gene ID 1956
NCBI Accession NP_005219
UniProt P00533
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling References for anti-EGFR Antibody (ABIN401341) Images back to top
Application Notes ELISA: 1/4,000 - 1/20,000. Western Blot 1/250 - 1/5,000. Immunohistochemistry: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details References for anti-EGFR Antibody (ABIN401341) Images back to top
Concentration 0.55 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

References for anti-EGFR Antibody (ABIN401341)

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling Images back to top
Background publications

Sibilia, Fleischmann, Behrens, Stingl, Carroll, Watt, Schlessinger, Wagner: "The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development." in: Cell, Vol. 102, Issue 2, pp. 211-20, 2000

Sartor, Dziubinski, Yu, Jove, Ethier: "Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells." in: Cancer research, Vol. 57, Issue 5, pp. 978-87, 1997

Scambia, Catozzi, Panici, Ferrandina, Coronetta, Barozzi, Baiocchi, Uccelli, Piffanelli, Mancuso: "Expression of ras oncogene p21 protein in normal and neoplastic ovarian tissues: correlation with histopathologic features and receptors for estrogen, progesterone, and epidermal growth factor." in: American journal of obstetrics and gynecology, Vol. 168, Issue 1 Pt 1, pp. 71-8, 1993

Henzen-Logmans, van der Burg, Foekens, Berns, Brussée, Fieret, Klijn, Chadha, Rodenburg: "Occurrence of epidermal growth factor receptors in benign and malignant ovarian tumors and normal ovarian tissues: an immunohistochemical study." in: Journal of cancer research and clinical oncology, Vol. 118, Issue 4, pp. 303-7, 1992

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling References for anti-EGFR Antibody (ABIN401341) back to top
Supplier Images
 image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (AA 1189-1199) (ABIN401341) anti-Epidermal Growth Factor Receptor (EGFR) (AA 1189-1199), (pTyr1197) antibody
 image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (AA 1189-1199) (ABIN401341) anti-Epidermal Growth Factor Receptor (EGFR) (AA 1189-1199), (pTyr1197) antibody (Image 2)