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anti-Rat (Meriones) EGFR antibody for Western Blotting

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • AaeL_AAEL004319
  • LOC100008806
Reactivity
Human, Mouse (Murine), Rat (Meriones)
2314
883
736
30
24
18
18
15
15
5
4
2
2
1
Host
Rabbit
1431
777
69
45
8
2
1
Clonality
Polyclonal
Conjugate
This EGFR antibody is un-conjugated
98
77
67
60
50
48
25
25
24
24
24
23
23
23
23
23
23
23
23
22
21
21
21
21
21
20
19
19
18
2
2
2
1
Application
Western Blotting (WB)
1367
599
597
485
466
272
229
228
108
87
70
55
35
22
19
12
11
8
6
5
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN2801937
$ 324.50
Plus shipping costs $45.00

Top referenced anti-EGFR antibody for Western Blotting

Similar anti-EGFR Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Meriones)
Immunofluorescence (fixed cells) (IF/ICC) 21 Antibodies 14 Antibodies
Cytometry by Time of Flight (CyTOF) 35 Antibodies 4 Antibodies
Simple Western (SimWes) 4 Antibodies
Western Blotting (WB) 1357 Antibodies 588 Antibodies 1 Antibodies
Radioimmunoassay (RIA) 1 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies 1 Antibodies
Neutralization (Neut) 12 Antibodies
Luminex Assay (LMNX) 11 Antibodies
Intracellular Staining (ICS) 2 Antibodies 2 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Inhibition Assay (InhA) 2 Antibodies

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Reactivity Human, Mouse (Murine), Rat (Meriones)
(2314), (883), (736), (30), (24), (18), (18), (15), (15), (5), (4), (2), (2), (1)
Host Rabbit
(1431), (777), (69), (45), (8), (2), (1)
Clonality
Polyclonal
Conjugate This EGFR antibody is un-conjugated
(98), (77), (67), (60), (50), (48), (25), (25), (24), (24), (24), (23), (23), (23), (23), (23), (23), (23), (23), (22), (21), (21), (21), (21), (21), (20), (19), (19), (18), (2), (2), (2), (1)
Application Western Blotting (WB)
(1367), (599), (597), (485), (466), (272), (229), (228), (108), (87), (70), (55), (35), (22), (19), (12), (11), (8), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling References for anti-EGFR Antibody (ABIN2801937) Images
Isotype IgG

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling References for anti-EGFR Antibody (ABIN2801937) Images back to top
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Background Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin.
Synonyms: Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1
Molecular Weight 134277 Da
Gene ID 1956
UniProt P00533
Research Area Cancer, Tyrosine Kinases, Growth Factors, Hormones, Receptors
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling References for anti-EGFR Antibody (ABIN2801937) Images back to top
Application Notes WB - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details References for anti-EGFR Antibody (ABIN2801937) Images back to top
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-EGFR Antibody (ABIN2801937)

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling Images back to top
Product cited in:

Reiter, Threadgill, Eley, Strunk, Danielsen, Sinclair, Pearsall, Green, Yee, Lampland, Balasubramaniam, Crossley, Magnuson, James, Maihle: "Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms." in: Genomics, Vol. 71, Issue 1, pp. 1-20, 2001

Ilekis, Gariti, Niederberger, Scoccia: "Expression of a truncated epidermal growth factor receptor-like protein (TEGFR) in ovarian cancer." in: Gynecologic oncology, Vol. 65, Issue 1, pp. 36-41, 1997

Reiter, Maihle: "A 1.8 kb alternative transcript from the human epidermal growth factor receptor gene encodes a truncated form of the receptor." in: Nucleic acids research, Vol. 24, Issue 20, pp. 4050-6, 1996

Ilekis, Stark, Scoccia: "Possible role of variant RNA transcripts in the regulation of epidermal growth factor receptor expression in human placenta." in: Molecular reproduction and development, Vol. 41, Issue 2, pp. 149-56, 1995

Ullrich, Coussens, Hayflick, Dull, Gray, Tam, Lee, Yarden, Libermann, Schlessinger: "Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells." in: Nature, Vol. 309, Issue 5967, pp. 418-25, 1984

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling References for anti-EGFR Antibody (ABIN2801937) back to top
Supplier Images
Western Blotting (WB) image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (ABIN2801937) anti-Epidermal Growth Factor Receptor (EGFR) antibody
Western Blotting (WB) image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (ABIN2801937) anti-Epidermal Growth Factor Receptor (EGFR) antibody (Image 2)